Xuewei Dong
Xuewei Dong
Assistant Professor, Soochow University
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Liquid–liquid phase separation of tau protein is encoded at the monomeric level
X Dong, S Bera, Q Qiao, Y Tang, Z Lao, Y Luo, E Gazit, G Wei
The journal of physical chemistry letters 12 (10), 2576-2586, 2021
Binding of protofibrillar Aβ trimers to lipid bilayer surface enhances Aβ structural stability and causes membrane thinning
X Dong, Y Sun, G Wei, R Nussinov, B Ma
Physical Chemistry Chemical Physics 19 (40), 27556-27569, 2017
Recent computational studies of membrane interaction and disruption of human islet amyloid polypeptide: Monomers, oligomers and protofibrils
X Dong, Q Qiao, Z Qian, G Wei
Biochimica et Biophysica Acta (BBA)-Biomembranes 1860 (9), 1826-1839, 2018
The distinct structural preferences of tau protein repeat domains
X Li, X Dong, G Wei, M Margittai, R Nussinov, B Ma
Chemical communications 54 (45), 5700-5703, 2018
Molecular mechanisms of resveratrol and EGCG in the inhibition of Aβ 42 aggregation and disruption of Aβ 42 protofibril: Similarities and differences
F Li, C Zhan, X Dong, G Wei
Physical Chemistry Chemical Physics 23 (34), 18843-18854, 2021
Prediction and characterization of liquid-liquid phase separation of minimalistic peptides
Y Tang, S Bera, Y Yao, J Zeng, Z Lao, X Dong, E Gazit, G Wei
Cell Reports Physical Science 2 (9), 2021
A comprehensive insight into the mechanisms of dopamine in disrupting Aβ protofibrils and inhibiting Aβ aggregation
Y Chen, X Li, C Zhan, Z Lao, F Li, X Dong, G Wei
ACS Chemical Neuroscience 12 (21), 4007-4019, 2021
Mechanistic insights into the co-aggregation of Aβ and hIAPP: an all-atom molecular dynamic study
X Li, Z Lao, Y Zou, X Dong, L Li, G Wei
The Journal of Physical Chemistry B 125 (8), 2050-2060, 2021
Green tea extract EGCG plays a dual role in Aβ42 protofibril disruption and membrane protection: A molecular dynamic study
X Dong, Y Tang, C Zhan, G Wei
Chemistry and Physics of Lipids 234, 105024, 2021
Heparin remodels the microtubule-binding repeat R3 of Tau protein towards fibril-prone conformations
X Dong, R Qi, Q Qiao, X Li, F Li, J Wan, Q Zhang, G Wei
Physical Chemistry Chemical Physics 23 (36), 20406-20418, 2021
Insights into the atomistic mechanisms of phosphorylation in disrupting liquid–liquid phase separation and aggregation of the FUS low-complexity domain
Z Lao, X Dong, X Liu, F Li, Y Chen, Y Tang, G Wei
Journal of Chemical Information and Modeling 62 (13), 3227-3238, 2022
Molecular dynamics simulations reveal the destabilization mechanism of Alzheimer's disease-related tau R3-R4 Protofilament by norepinephrine
J Wan, Y Gong, Z Xu, X Dong, G Wei, Q Zhang
Biophysical chemistry 271, 106541, 2021
Solid-state packing dictates the unexpected solubility of aromatic peptides
S Bera, X Dong, B Krishnarjuna, SA Raab, DA Hales, W Ji, Y Tang, ...
Cell Reports Physical Science 2 (4), 2021
The destructive mechanism of Aβ 1–42 protofibrils by norepinephrine revealed via molecular dynamics simulations
D Gao, J Wan, Y Zou, Y Gong, X Dong, Z Xu, J Tang, G Wei, Q Zhang
Physical Chemistry Chemical Physics 24 (33), 19827-19836, 2022
ALS-associated A315E and A315pT variants exhibit distinct mechanisms in inducing irreversible aggregation of TDP-43 312–317 peptides
X Liu, Z Lao, X Li, X Dong, G Wei
Physical Chemistry Chemical Physics 24 (26), 16263-16273, 2022
Atomistic insights into A315E mutation-enhanced pathogenicity of TDP-43 core fibrils
F Li, Y Chen, X Liu, Y Tang, X Dong, G Wei
ACS Chemical Neuroscience 13 (18), 2743-2754, 2022
Influence of ALS‐linked M337V mutation on the conformational ensembles of TDP‐43321–340 peptide monomer and dimer
J Zeng, Y Tang, X Dong, F Li, G Wei
Proteins: Structure, Function, and Bioinformatics, 2023
Deciphering the mechanisms of HPV E6 mutations in the destabilization of E6/E6AP/p53 complex
L Li, X Dong, Y Tang, Z Lao, X Li, J Lei, G Wei
Biophysical Journal 121 (9), 1704-1714, 2022
Mechanistic insight into the destabilization of p53TD tetramer by cancer-related R337H mutation: a molecular dynamics study
Y Yu, X Dong, Y Tang, L Li, G Wei
Physical Chemistry Chemical Physics 24 (8), 5199-5210, 2022
Insight into Biophysicochemical Principles of Biopolymers through Simulation and Theory
HX Wan, D Xu, XW Dong, K Yang, LT Yan
Chinese Journal of Polymer Science, 1-13, 2023
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