Liquid–liquid phase separation of tau protein is encoded at the monomeric level X Dong, S Bera, Q Qiao, Y Tang, Z Lao, Y Luo, E Gazit, G Wei The journal of physical chemistry letters 12 (10), 2576-2586, 2021 | 40 | 2021 |
Binding of protofibrillar Aβ trimers to lipid bilayer surface enhances Aβ structural stability and causes membrane thinning X Dong, Y Sun, G Wei, R Nussinov, B Ma Physical Chemistry Chemical Physics 19 (40), 27556-27569, 2017 | 32 | 2017 |
Recent computational studies of membrane interaction and disruption of human islet amyloid polypeptide: Monomers, oligomers and protofibrils X Dong, Q Qiao, Z Qian, G Wei Biochimica et Biophysica Acta (BBA)-Biomembranes 1860 (9), 1826-1839, 2018 | 31 | 2018 |
The distinct structural preferences of tau protein repeat domains X Li, X Dong, G Wei, M Margittai, R Nussinov, B Ma Chemical communications 54 (45), 5700-5703, 2018 | 30 | 2018 |
Molecular mechanisms of resveratrol and EGCG in the inhibition of Aβ 42 aggregation and disruption of Aβ 42 protofibril: Similarities and differences F Li, C Zhan, X Dong, G Wei Physical Chemistry Chemical Physics 23 (34), 18843-18854, 2021 | 29 | 2021 |
Prediction and characterization of liquid-liquid phase separation of minimalistic peptides Y Tang, S Bera, Y Yao, J Zeng, Z Lao, X Dong, E Gazit, G Wei Cell Reports Physical Science 2 (9), 2021 | 24 | 2021 |
A comprehensive insight into the mechanisms of dopamine in disrupting Aβ protofibrils and inhibiting Aβ aggregation Y Chen, X Li, C Zhan, Z Lao, F Li, X Dong, G Wei ACS Chemical Neuroscience 12 (21), 4007-4019, 2021 | 21 | 2021 |
Mechanistic insights into the co-aggregation of Aβ and hIAPP: an all-atom molecular dynamic study X Li, Z Lao, Y Zou, X Dong, L Li, G Wei The Journal of Physical Chemistry B 125 (8), 2050-2060, 2021 | 18 | 2021 |
Green tea extract EGCG plays a dual role in Aβ42 protofibril disruption and membrane protection: A molecular dynamic study X Dong, Y Tang, C Zhan, G Wei Chemistry and Physics of Lipids 234, 105024, 2021 | 18 | 2021 |
Heparin remodels the microtubule-binding repeat R3 of Tau protein towards fibril-prone conformations X Dong, R Qi, Q Qiao, X Li, F Li, J Wan, Q Zhang, G Wei Physical Chemistry Chemical Physics 23 (36), 20406-20418, 2021 | 14 | 2021 |
Insights into the atomistic mechanisms of phosphorylation in disrupting liquid–liquid phase separation and aggregation of the FUS low-complexity domain Z Lao, X Dong, X Liu, F Li, Y Chen, Y Tang, G Wei Journal of Chemical Information and Modeling 62 (13), 3227-3238, 2022 | 13 | 2022 |
Molecular dynamics simulations reveal the destabilization mechanism of Alzheimer's disease-related tau R3-R4 Protofilament by norepinephrine J Wan, Y Gong, Z Xu, X Dong, G Wei, Q Zhang Biophysical chemistry 271, 106541, 2021 | 13 | 2021 |
Solid-state packing dictates the unexpected solubility of aromatic peptides S Bera, X Dong, B Krishnarjuna, SA Raab, DA Hales, W Ji, Y Tang, ... Cell Reports Physical Science 2 (4), 2021 | 7 | 2021 |
The destructive mechanism of Aβ 1–42 protofibrils by norepinephrine revealed via molecular dynamics simulations D Gao, J Wan, Y Zou, Y Gong, X Dong, Z Xu, J Tang, G Wei, Q Zhang Physical Chemistry Chemical Physics 24 (33), 19827-19836, 2022 | 6 | 2022 |
ALS-associated A315E and A315pT variants exhibit distinct mechanisms in inducing irreversible aggregation of TDP-43 312–317 peptides X Liu, Z Lao, X Li, X Dong, G Wei Physical Chemistry Chemical Physics 24 (26), 16263-16273, 2022 | 5 | 2022 |
Atomistic insights into A315E mutation-enhanced pathogenicity of TDP-43 core fibrils F Li, Y Chen, X Liu, Y Tang, X Dong, G Wei ACS Chemical Neuroscience 13 (18), 2743-2754, 2022 | 4 | 2022 |
Influence of ALS‐linked M337V mutation on the conformational ensembles of TDP‐43321–340 peptide monomer and dimer J Zeng, Y Tang, X Dong, F Li, G Wei Proteins: Structure, Function, and Bioinformatics, 2023 | 3 | 2023 |
Deciphering the mechanisms of HPV E6 mutations in the destabilization of E6/E6AP/p53 complex L Li, X Dong, Y Tang, Z Lao, X Li, J Lei, G Wei Biophysical Journal 121 (9), 1704-1714, 2022 | 3 | 2022 |
Mechanistic insight into the destabilization of p53TD tetramer by cancer-related R337H mutation: a molecular dynamics study Y Yu, X Dong, Y Tang, L Li, G Wei Physical Chemistry Chemical Physics 24 (8), 5199-5210, 2022 | 3 | 2022 |
Insight into Biophysicochemical Principles of Biopolymers through Simulation and Theory HX Wan, D Xu, XW Dong, K Yang, LT Yan Chinese Journal of Polymer Science, 1-13, 2023 | 1 | 2023 |