| Human mitochondrial DNA replication machinery and disease MJ Young, WC Copeland Current opinion in genetics & development 38, 52-62, 2016 | 182 | 2016 |
| The evolutionary history of mitochondrial porins MJ Young, DC Bay, G Hausner, DA Court BMC evolutionary biology 7, 1-21, 2007 | 157 | 2007 |
| The evolutionary history of mitochondrial porins MJ Young, DC Bay, G Hausner, DA Court BMC evolutionary biology 7, 1-21, 2007 | 157 | 2007 |
| Polg2 is essential for mammalian embryogenesis and is required for mtDNA maintenance MM Humble, MJ Young, JF Foley, AR Pandiri, GS Travlos, WC Copeland Human molecular genetics 22 (5), 1017-1025, 2013 | 80 | 2013 |
| Off-target effects of drugs that disrupt human mitochondrial DNA maintenance MJ Young Frontiers in molecular biosciences 4, 74, 2017 | 72 | 2017 |
| Biochemical analysis of human POLG2 variants associated with mitochondrial disease MJ Young, MJ Longley, FY Li, R Kasiviswanathan, LJ Wong, ... Human molecular genetics 20 (15), 3052-3066, 2011 | 68 | 2011 |
| Phylogenetic and coevolutionary analysis of the β-barrel protein family comprised of mitochondrial porin (VDAC) and Tom40 DC Bay, M Hafez, MJ Young, DA Court Biochimica et Biophysica Acta (BBA)-Biomembranes 1818 (6), 1502-1519, 2012 | 49 | 2012 |
| Effects of the S288c genetic background and common auxotrophic markers on mitochondrial DNA function in Saccharomyces cerevisiae MJ Young, DA Court Yeast 25 (12), 903-912, 2008 | 38 | 2008 |
| POLG2 disease variants: analyses reveal a dominant negative heterodimer, altered mitochondrial localization and impaired respiratory capacity MJ Young, MM Humble, KL DeBalsi, KY Sun, WC Copeland Human molecular genetics 24 (18), 5184-5197, 2015 | 31 | 2015 |
| A p. R369G POLG2 mutation associated with adPEO and multiple mtDNA deletions causes decreased affinity between polymerase γ subunits K Craig, MJ Young, EL Blakely, MJ Longley, DM Turnbull, WC Copeland, ... Mitochondrion 12 (2), 313-319, 2012 | 27 | 2012 |
| Comparison of HepaRG cells following growth in proliferative and differentiated culture conditions reveals distinct bioenergetic profiles CKJ Young, MJ Young Cell Cycle 18 (4), 476-499, 2019 | 21 | 2019 |
| The antiretroviral 2′, 3′-dideoxycytidine causes mitochondrial dysfunction in proliferating and differentiated HepaRG human cell cultures CKJ Young, JH Wheeler, MM Rahman, MJ Young Journal of Biological Chemistry 296, 2021 | 19 | 2021 |
| Purification and functional characterization of human mitochondrial DNA polymerase gamma harboring disease mutations R Kasiviswanathan, MJ Longley, MJ Young, WC Copeland Methods 51 (4), 379-384, 2010 | 19 | 2010 |
| The carboxyl‐terminal extension on fungal mitochondrial DNA polymerases: identification of a critical region of the enzyme from Saccharomyces cerevisiae MJ Young, SS Theriault, M Li, DA Court Yeast 23 (2), 101-116, 2006 | 17 | 2006 |
| The carboxyl‐terminal extension on fungal mitochondrial DNA polymerases: identification of a critical region of the enzyme from Saccharomyces cerevisiae MJ Young, SS Theriault, M Li, DA Court Yeast 23 (2), 101-116, 2006 | 17 | 2006 |
| Analysis of human mitochondrial DNA content by southern blotting and nonradioactive probe hybridization JH Wheeler, CKJ Young, MJ Young Current protocols in toxicology 80 (1), e75, 2019 | 11 | 2019 |
| Mitochondrial disorders associated with the mitochondrial DNA polymerase g: a focus on intersubunit interactions MJ Young, WC Copeland Mitochondrial Disorders Caused by Nuclear Genes, 49-72, 2013 | 8 | 2013 |
| Remdesivir triphosphate blocks DNA synthesis and increases exonucleolysis by the replicative mitochondrial DNA polymerase, Pol γ EJ Ciesielska, S Kim, MB Hyacintha-ghislaine, C Grier, MM Rahman, ... Mitochondrion 61, 147-158, 2021 | 6 | 2021 |
| Analysis of mitochondrial DNA polymorphisms in the human cell lines HepaRG and SJCRH30 MJ Young, AD Jayaprakash, CKJ Young International Journal of Molecular Sciences 20 (13), 3245, 2019 | 5 | 2019 |
| Identification of somatic mitochondrial DNA mutations, heteroplasmy, and increased levels of catenanes in tumor specimens obtained from three endometrial cancer patients MJ Young, R Sachidanandam, DB Hales, L Brard, K Robinson, ... Life 12 (4), 562, 2022 | 3 | 2022 |
Deborah A. CourtProfessor of Microbiology, University of ManitobaПотвърден имейл адрес: umanitoba.ca
