Следене
George Vassiliou
George Vassiliou
Professor of Haematological Medicine, University of Cambridge & Cambridge Stem Cell Institute
Потвърден имейл адрес: sanger.ac.uk - Начална страница
Заглавие
Позовавания
Позовавания
Година
Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders
EJ Baxter, LM Scott, PJ Campbell, C East, N Fourouclas, S Swanton, ...
The Lancet 365 (9464), 1054-1061, 2005
46172005
Promoter-bound METTL3 maintains myeloid leukaemia by m6A-dependent translation control
I Barbieri, K Tzelepis, L Pandolfini, J Shi, G Millán-Zambrano, SC Robson, ...
Nature 552 (7683), 126-131, 2017
9072017
Definition of subtypes of essential thrombocythaemia and relation to polycythaemia vera based on JAK2 V617F mutation status: a prospective study
PJ Campbell, LM Scott, G Buck, K Wheatley, CL East, JT Marsden, A Duffy, ...
The Lancet 366 (9501), 1945-1953, 2005
8972005
Prediction of acute myeloid leukaemia risk in healthy individuals
S Abelson, G Collord, SWK Ng, O Weissbrod, N Mendelson Cohen, ...
Nature 559 (7714), 400-404, 2018
7962018
Small-molecule inhibition of METTL3 as a strategy against myeloid leukaemia
E Yankova, W Blackaby, M Albertella, J Rak, E De Braekeleer, ...
Nature 593 (7860), 597-601, 2021
6482021
A CRISPR dropout screen identifies genetic vulnerabilities and therapeutic targets in acute myeloid leukemia
K Tzelepis, H Koike-Yusa, E De Braekeleer, Y Li, E Metzakopian, ...
Cell reports 17 (4), 1193-1205, 2016
6432016
Effect of mutation order on myeloproliferative neoplasms
CA Ortmann, DG Kent, J Nangalia, Y Silber, DC Wedge, J Grinfeld, ...
New England Journal of Medicine 372 (7), 601-612, 2015
6012015
Leukemia-associated somatic mutations drive distinct patterns of age-related clonal hemopoiesis
T McKerrell, N Park, T Moreno, CS Grove, H Ponstingl, J Stephens, ...
Cell reports 10 (8), 1239-1245, 2015
5312015
Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer
YS Ju, LB Alexandrov, M Gerstung, I Martincorena, S Nik-Zainal, ...
elife 3, e02935, 2014
4012014
Evolutionary routes and KRAS dosage define pancreatic cancer phenotypes
S Mueller, T Engleitner, R Maresch, M Zukowska, S Lange, ...
Nature 554 (7690), 62-68, 2018
3792018
PPM1D mutations drive clonal hematopoiesis in response to cytotoxic chemotherapy
JI Hsu, T Dayaram, A Tovy, E De Braekeleer, M Jeong, F Wang, J Zhang, ...
Cell stem cell 23 (5), 700-713. e6, 2018
3212018
PiggyBac transposon mutagenesis: a tool for cancer gene discovery in mice
R Rad, L Rad, W Wang, J Cadinanos, G Vassiliou, S Rice, LS Campos, ...
Science 330 (6007), 1104-1107, 2010
2892010
Mutant nucleophosmin and cooperating pathways drive leukemia initiation and progression in mice
GS Vassiliou, JL Cooper, R Rad, J Li, S Rice, A Uren, L Rad, P Ellis, ...
Nature genetics 43 (5), 470-475, 2011
2642011
Acute myeloid leukaemia: a paradigm for the clonal evolution of cancer?
CS Grove, GS Vassiliou
Disease models & mechanisms 7 (8), 941-951, 2014
2502014
A genetic progression model of BrafV600E-induced intestinal tumorigenesis reveals targets for therapeutic intervention
R Rad, J Cadiñanos, L Rad, I Varela, A Strong, L Kriegl, ...
Cancer cell 24 (1), 15-29, 2013
2442013
CRISPR/Cas9 somatic multiplex-mutagenesis for high-throughput functional cancer genomics in mice
J Weber, R Öllinger, M Friedrich, U Ehmer, M Barenboim, K Steiger, I Heid, ...
Proceedings of the National Academy of Sciences 112 (45), 13982-13987, 2015
2192015
Clonal dynamics of haematopoiesis across the human lifespan
E Mitchell, M Spencer Chapman, N Williams, KJ Dawson, N Mende, ...
Nature 606 (7913), 343-350, 2022
2142022
Targeting Chromatin Regulators Inhibits Leukemogenic Gene Expression in NPM1 Mutant Leukemia
MWM Kühn, E Song, Z Feng, A Sinha, CW Chen, AJ Deshpande, ...
Cancer discovery 6 (10), 1166-1181, 2016
2092016
Multiplexed pancreatic genome engineering and cancer induction by transfection-based CRISPR/Cas9 delivery in mice
R Maresch, S Mueller, C Veltkamp, R Öllinger, M Friedrich, I Heid, ...
Nature communications 7 (1), 10770, 2016
2012016
The longitudinal dynamics and natural history of clonal haematopoiesis
MA Fabre, JG de Almeida, E Fiorillo, E Mitchell, A Damaskou, J Rak, ...
Nature 606 (7913), 335-342, 2022
1932022
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Статии 1–20