Steven Boeynaems
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Protein phase separation: a new phase in cell biology
S Boeynaems, S Alberti, NL Fawzi, T Mittag, M Polymenidou, F Rousseau, ...
Trends in cell biology 28 (6), 420-435, 2018
Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS
A Jovičić, J Mertens, S Boeynaems, E Bogaert, N Chai, SB Yamada, ...
Nature neuroscience 18 (9), 1226-1229, 2015
Phase separation of C9orf72 dipeptide repeats perturbs stress granule dynamics
S Boeynaems, E Bogaert, D Kovacs, A Konijnenberg, E Timmerman, ...
Molecular cell 65 (6), 1044-1055. e5, 2017
Spontaneous driving forces give rise to protein− RNA condensates with coexisting phases and complex material properties
S Boeynaems, AS Holehouse, V Weinhardt, D Kovacs, J Van Lindt, ...
Proceedings of the National Academy of Sciences 116 (16), 7889-7898, 2019
Drosophila screen connects nuclear transport genes to DPR pathology in c9ALS/FTD
S Boeynaems*, E Bogaert*, E Michiels, I Gijselinck, A Sieben, A Jovičić, ...
Scientific reports 6, 2016
Beyond junk-variable tandem repeats as facilitators of rapid evolution of regulatory and coding sequences
R Gemayel, J Cho, S Boeynaems, KJ Verstrepen
Genes 3 (3), 461-480, 2012
A prion-like protein regulator of seed germination undergoes hydration-dependent phase separation
Y Dorone*, S Boeynaems*, E Flores, B Jin, S Hateley, F Bossi, E Lazarus, ...
Cell, 2021
A zebrafish model for C9orf72 ALS reveals RNA toxicity as a pathogenic mechanism
B Swinnen, A Bento-Abreu, TF Gendron, S Boeynaems, E Bogaert, ...
Acta neuropathologica 135, 427-443, 2018
Inside out: the role of nucleocytoplasmic transport in ALS and FTLD
S Boeynaems, E Bogaert, P Van Damme, L Van Den Bosch
Acta neuropathologica 132, 159-173, 2016
Variable glutamine-rich repeats modulate transcription factor activity
R Gemayel, S Chavali, K Pougach, M Legendre, B Zhu, S Boeynaems, ...
Molecular cell 59 (4), 615-627, 2015
Molecular dissection of FUS points at synergistic effect of low-complexity domains in toxicity
E Bogaert*, S Boeynaems*, M Kato, L Guo, TR Caulfield, J Steyaert, ...
Cell reports 24 (3), 529-537. e4, 2018
The material properties of a bacterial-derived biomolecular condensate tune biological function in natural and synthetic systems
K Lasker, S Boeynaems, V Lam, D Scholl, E Stainton, A Briner, ...
Nature Communications 13 (1), 5643, 2022
C9orf72-derived arginine-containing dipeptide repeats associate with axonal transport machinery and impede microtubule-based motility
L Fumagalli*, FL Young*, S Boeynaems*, M De Decker, AR Mehta, ...
Science Advances 7 (15), eabg3013, 2021
HDAC6 inhibition restores TDP‐43 pathology and axonal transport defects in human motor neurons with TARDBP mutations
R Fazal, S Boeynaems, A Swijsen, M De Decker, L Fumagalli, M Moisse, ...
The EMBO journal 40 (7), e106177, 2021
C9orf72-generated poly-GR and poly-PR do not directly interfere with nucleocytoplasmic transport
J Vanneste, T Vercruysse, S Boeynaems, A Sicart, P Van Damme, ...
Scientific reports 9 (1), 15728, 2019
ATXN1 repeat expansions confer risk for amyotrophic lateral sclerosis and contribute to TDP-43 mislocalization
GHP Tazelaar*, S Boeynaems*, M De Decker*, JJFA van Vugt, L Kool, ...
Brain communications 2 (2), fcaa064, 2020
Dynamic mapping of proteome trafficking within and between living cells by TransitID
W Qin, JS Cheah, C Xu, J Messing, BD Freibaum, S Boeynaems, ...
Cell 186 (15), 3307-3324.e30, 2023
Designer condensates: a toolkit for the biomolecular architect
RL Hastings, S Boeynaems
Journal of Molecular Biology 433 (12), 166837, 2021
Symmetric dimethylation of poly-GR correlates with disease duration in C9orf72 FTLD and ALS and reduces poly-GR phase separation and toxicity
LM Gittings, S Boeynaems, D Lightwood, A Clargo, S Topia, L Nakayama, ...
Acta neuropathologica 139, 407-410, 2020
Phasing in on the cell cycle
S Boeynaems, P Tompa, L Van Den Bosch
Cell Division 13, 1-8, 2018
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