Следене
Onuralp Soylemez
Onuralp Soylemez
Harvard Medical School
Потвърден имейл адрес: broadinstitute.org
Заглавие
Позовавания
Позовавания
Година
Local fitness landscape of the green fluorescent protein
KS Sarkisyan, DA Bolotin, MV Meer, DR Usmanova, AS Mishin, ...
Nature 533 (7603), 397-401, 2016
5562016
Structure and evolutionary history of a large family of NLR proteins in the zebrafish
K Howe, S Philipp, J Zielinski, T Wiehe, G Laird, J Marioni, O Soylemez, ...
bioRxiv, 2015
1112015
Estimating the rate of irreversibility in protein evolution
O Soylemez, FA Kondrashov
Genome Biology and Evolution 4 (12), 1213-1222, 2012
442012
Evidence for secondary-variant genetic burden and non-random distribution across biological modules in a recessive ciliopathy
M Kousi, O Söylemez, A Ozanturk, N Mourtzi, S Akle, I Jungreis, J Muller, ...
Nature genetics 52 (11), 1145-1150, 2020
342020
Massively parallel enzyme kinetics reveals the substrate recognition landscape of the metalloprotease ADAMTS13
K Colin, M Dai, O Soylemez, A Yee, K Desch, D Siemieniak, K Tomberg, ...
Proceedings of the National Academy of Sciences, 2015
262015
An integrated clinical program and crowdsourcing strategy for genomic sequencing and Mendelian disease gene discovery
A Haghighi, JB Krier, A Toth-Petroczy, CA Cassa, NY Frank, ...
NPJ genomic medicine 3 (1), 21, 2018
242018
Low-frequency inherited complement receptor variants are associated with purpura fulminans
PK Bendapudi, S Nazeen, J Ryu, O Söylemez, A Robbins, B Rouaisnel, ...
Blood 143 (11), 1032-1044, 2024
22024
Evaluation and optimization of sequence-based gene regulatory deep learning models
AM Rafi, D Nogina, D Penzar, D Lee, D Lee, N Kim, S Kim, D Kim, Y Shin, ...
bioRxiv, 2023
22023
Rare inherited defects of the complement system in purpura fulminans
P Bendapudi, J Ryu, O Soylemez, B Rouaisnel, M Colling, B Pasko, ...
Blood 136, 35-36, 2020
22020
Protein language model rescue mutations highlight variant effects and structure in clinically relevant genes
O Soylemez, P Cordero
NeurIPS 2022, Workshop on Learning Meaningful Representations of Life, 2022
12022
Pathway-based rare variant burden analysis identifies a role for the complement system in an extreme phenotype of sepsis with coagulopathy
PK Bendapudi, S Nazeen, J Ryu, O Söylemez, B Rouaisnel, M Colling, ...
Medrxiv, 2022.02. 24.22271459, 2022
12022
Investigating Gene Expression Signatures and Cell-Type Composition Changes in Sickle Cell Disease Using Whole Blood Transcriptomics
AA Potdar, M Caponegro, O Soylemez, A Reddy, K Yu
Blood 140 (Supplement 1), 5403-5404, 2022
2022
Bayesian tensor factorization for predicting clinical outcomes using integrated human genetics evidence
O Soylemez
arXiv preprint arXiv:2207.12538, 2022
2022
Bayesian tensor factorization for predicting clinical outcomes using integrated human genetics evidence
O Soylemez
ICML 2022, Workshop on Computational Biology, 2022
2022
Appendix 1. Working Group Members
D An, S Akasha, U Ben-David, E Blackwell, R Bhattacharyya, A Biasella, ...
2016
On the prevalence and role of epistasis in shaping fitness within and between populations
O Söylemez
Universitat Pompeu Fabra, 2016
2016
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Статии 1–16