Nikki Copeland
Nikki Copeland
Senior Lecturer in Biomedicine, Lancaster University
Потвърден имейл адрес: lancaster.ac.uk - Начална страница
Supramolecular assemblies underpin turnover of outer membrane proteins in bacteria
P Rassam, NA Copeland, O Birkholz, C Tóth, M Chavent, AL Duncan, ...
Nature 523 (7560), 333-336, 2015
Ciz1 cooperates with cyclin-A–CDK2 to activate mammalian DNA replication in vitro
NA Copeland, HE Sercombe, JFX Ainscough, D Coverley
Journal of cell science 123 (7), 1108-1115, 2010
Cancer‐associated missplicing of exon 4 influences the subnuclear distribution of the DNA replication factor CIZ1
FA Rahman, JFX Ainscough, N Copeland, D Coverley
Human mutation 28 (10), 993-1004, 2007
Cyclin‐A–CDK2‐mediated phosphorylation of CIZ1 blocks replisome formation and initiation of mammalian DNA replication
NA Copeland, HE Sercombe, RHC Wilson, D Coverley
Journal of Cell Science 128 (8), 1518-1527, 2015
NUDT2 Disruption Elevates Diadenosine Tetraphosphate (Ap4A) and Down-Regulates Immune Response and Cancer Promotion Genes
AS Marriott, O Vasieva, Y Fang, NA Copeland, AG McLennan, NJ Jones
PLoS One 11 (5), e0154674, 2016
Re-evaluation of Diadenosine Tetraphosphate (Ap4A) From a Stress Metabolite to Bona Fide Secondary Messenger
F Ferguson, AG McLennan, MD Urbaniak, NJ Jones, NA Copeland
Frontiers in Molecular Biosciences 7, 606807, 2020
Cancer-associated variant expression and interaction of CIZ1 with cyclin A1 in differentiating male germ cells
EA Greaves, NA Copeland, D Coverley, JFX Ainscough
Journal of cell science 125 (10), 2466-2477, 2012
Emerging roles for Ciz1 in cell cycle regulation and as a driver of tumorigenesis
T Pauzaite, U Thacker, J Tollitt, NA Copeland
Biomolecules 7 (1), 1, 2016
Diadenosine 5′, 5′′′-P1, P4-tetraphosphate (Ap4A) is synthesized in response to DNA damage and inhibits the initiation of DNA replication
AS Marriott, NA Copeland, R Cunningham, MC Wilkinson, AG McLennan, ...
DNA repair 33, 90-100, 2015
Cyclin E is recruited to the nuclear matrix during differentiation, but is not recruited in cancer cells
J Munkley, NA Copeland, V Moignard, JRP Knight, E Greaves, ...
Nucleic acids research 39 (7), 2671-2677, 2011
Light-responsive biomaterials for ocular drug delivery
HAM Abdelmohsen, NA Copeland, JG Hardy
Drug Delivery and Translational Research 13 (8), 2159-2182, 2023
The role of an activating peptide in protease-mediated suicide of Escherichia coli K12
NA Copeland, C Kleanthous
Journal of Biological Chemistry 280 (1), 112-117, 2005
Detection of CRISPR-Cas9-mediated mutations using a carbon nanotube-modified electrochemical genosensor
E Kivrak, T Pauzaite, NA Copeland, JG Hardy, P Kara, M Firlak, ...
Biosensors 11 (1), 17, 2021
Identification of DHX9 as a cell cycle regulated nucleolar recruitment factor for CIZ1
U Thacker, T Pauzaite, J Tollitt, M Twardowska, C Harrison, A Dowle, ...
Scientific Reports 10 (1), 18103, 2020
Identification of essential residues within Lit, a cell death peptidase of Escherichia coli K-12
NA Copeland, R Bingham, T Georgiou, P Cooper, C Kleanthous
Biochemistry 43 (24), 7948-7953, 2004
Dbf4-Cdc7 (DDK) Inhibitor PHA-767491 Displays Potent Anti-Proliferative Effects via Crosstalk with the CDK2-RB-E2F Pathway
T Pauzaite, J Tollitt, B Sopaci, L Caprani, O Iwanowytsch, U Thacker, ...
Biomedicines 10 (8), 2012, 2022
Lit Protease
NA Copeland, C Kleanthous
Handbook of Proteolytic Enzymes, 3761-3764, 2013
Identification of DHX9 as a cell cycle regulated nucleolar recruitment factor for CIZ1
T Urvi, P Tekle, J Tollitt, M Twardowska, C Harrison, D Adam, C Dawn, ...
Scientific Reports (Nature Publisher Group), 2020
Disruption of the nuclear matrix attachment domain of the DNA replication factor Ciz1 in common solid tumors and its potential as a biomarker
H Sercombe, G Higgins, J Munkley, N Copeland, K Roper, FA Rahman, ...
Cancer Research 71 (8_Supplement), 3022-3022, 2011
22-P003 Cyclin E is a conditional nuclear matrix protein
J Munkley, V Moignard, N Copeland, J Knight, E Greaves, J Southgate, ...
Mechanisms of development, S329, 2009
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Статии 1–20