| Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons JT Dimos, KT Rodolfa, KK Niakan, LM Weisenthal, H Mitsumoto, W Chung, ... science 321 (5893), 1218-1221, 2008 | 2538 | 2008 |
| Directed differentiation of embryonic stem cells into motor neurons H Wichterle, I Lieberam, JA Porter, TM Jessell Cell 110 (3), 385-397, 2002 | 2119 | 2002 |
| Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons M Nagai, DB Re, T Nagata, A Chalazonitis, TM Jessell, H Wichterle, ... Nature neuroscience 10 (5), 615-622, 2007 | 1423 | 2007 |
| New neurons follow the flow of cerebrospinal fluid in the adult brain K Sawamoto, H Wichterle, O Gonzalez-Perez, JA Cholfin, M Yamada, ... Science 311 (5761), 629-632, 2006 | 927 | 2006 |
| In utero fate mapping reveals distinct migratory pathways and fates of neurons born in the mammalian basal forebrain H Wichterle, DH Turnbull, S Nery, G Fishell, A Alvarez-Buylla Development 128 (19), 3759-3771, 2001 | 808 | 2001 |
| Architecture and cell types of the adult subventricular zone: in search of the stem cells JM García‐Verdugo, F Doetsch, H Wichterle, DA Lim, A Alvarez‐Buylla Journal of neurobiology 36 (2), 234-248, 1998 | 605 | 1998 |
| Small-molecule modulators of Hedgehog signaling: identification and characterization of Smoothened agonists and antagonists M Frank-Kamenetsky, XM Zhang, S Bottega, O Guicherit, H Wichterle, ... Journal of biology 1, 1-19, 2002 | 591 | 2002 |
| A functionally characterized test set of human induced pluripotent stem cells GL Boulting, E Kiskinis, GF Croft, MW Amoroso, DH Oakley, BJ Wainger, ... Nature biotechnology 29 (3), 279-286, 2011 | 580 | 2011 |
| Young neurons from medial ganglionic eminence disperse in adult and embryonic brain H Wichterle, JM Garcia-Verdugo, DG Herrera, A Alvarez-Buylla Nature neuroscience 2 (5), 461-466, 1999 | 569 | 1999 |
| Direct evidence for homotypic, glia-independent neuronal migration H Wichterle, JM García-Verdugo, A Alvarez-Buylla Neuron 18 (5), 779-791, 1997 | 528 | 1997 |
| Necroptosis drives motor neuron death in models of both sporadic and familial ALS DB Re, V Le Verche, C Yu, MW Amoroso, KA Politi, S Phani, B Ikiz, ... Neuron 81 (5), 1001-1008, 2014 | 458 | 2014 |
| An alternative splicing switch regulates embryonic stem cell pluripotency and reprogramming M Gabut, P Samavarchi-Tehrani, X Wang, V Slobodeniuc, D O'Hanlon, ... Cell 147 (1), 132-146, 2011 | 423 | 2011 |
| A requirement for retinoic acid-mediated transcriptional activation in ventral neural patterning and motor neuron specification BG Novitch, H Wichterle, TM Jessell, S Sockanathan Neuron 40 (1), 81-95, 2003 | 401 | 2003 |
| Sonic hedgehog contributes to oligodendrocyte specification in the mammalian forebrain S Nery, H Wichterle, G Fishell Development 128 (4), 527-540, 2001 | 393 | 2001 |
| Identification of a small molecule inhibitor of the hedgehog signaling pathway: effects on basal cell carcinoma-like lesions JA Williams, OM Guicherit, BI Zaharian, Y Xu, L Chai, H Wichterle, C Kon, ... Proceedings of the National Academy of Sciences 100 (8), 4616-4621, 2003 | 380 | 2003 |
| Modeling ALS with motor neurons derived from human induced pluripotent stem cells S Sances, LI Bruijn, S Chandran, K Eggan, R Ho, JR Klim, MR Livesey, ... Nature neuroscience 19 (4), 542-553, 2016 | 298 | 2016 |
| Functional properties of motoneurons derived from mouse embryonic stem cells GB Miles, DC Yohn, H Wichterle, TM Jessell, VF Rafuse, RM Brownstone Journal of Neuroscience 24 (36), 7848-7858, 2004 | 294 | 2004 |
| Accelerated high-yield generation of limb-innervating motor neurons from human stem cells MW Amoroso, GF Croft, DJ Williams, S O'Keeffe, MA Carrasco, AR Davis, ... Journal of Neuroscience 33 (2), 574-586, 2013 | 292 | 2013 |
| Multiprotein complexes of the survival of motor neuron protein SMN with Gemins traffic to neuronal processes and growth cones of motor neurons H Zhang, L Xing, W Rossoll, H Wichterle, RH Singer, GJ Bassell Journal of Neuroscience 26 (33), 8622-8632, 2006 | 253 | 2006 |
| MicroRNA regulation of neural stem cells and neurogenesis Y Shi, X Zhao, J Hsieh, H Wichterle, S Impey, S Banerjee, P Neveu, ... Journal of Neuroscience 30 (45), 14931-14936, 2010 | 241 | 2010 |
