Comprehensive computational design of ordered peptide macrocycles P Hosseinzadeh, G Bhardwaj, VK Mulligan, MD Shortridge, TW Craven, ... Science 358 (6369), 1461-1466, 2017 | 185 | 2017 |
Estimating protein− ligand binding affinity using high-throughput screening by NMR MD Shortridge, DS Hage, GS Harbison, R Powers Journal of combinatorial chemistry 10 (6), 948-958, 2008 | 115 | 2008 |
Development of small molecules with a noncanonical binding mode to HIV-1 trans activation response (TAR) RNA FA Abulwerdi, MD Shortridge, J Sztuba-Solinska, R Wilson, SFJ Le Grice, ... Journal of medicinal chemistry 59 (24), 11148-11160, 2016 | 96 | 2016 |
Structure based approaches for targeting non-coding RNAs with small molecules MD Shortridge, G Varani Current opinion in structural biology 30, 79-88, 2015 | 81 | 2015 |
Analysis of metabolomic PCA data using tree diagrams MT Werth, S Halouska, MD Shortridge, B Zhang, R Powers Analytical biochemistry 399 (1), 58-63, 2010 | 73 | 2010 |
A macrocyclic peptide ligand binds the oncogenic MicroRNA-21 precursor and suppresses dicer processing MD Shortridge, MJ Walker, T Pavelitz, Y Chen, W Yang, G Varani ACS chemical biology 12 (6), 1611-1620, 2017 | 70 | 2017 |
An ultra-high affinity ligand of HIV-1 TAR reveals the RNA structure recognized by P-TEFb MD Shortridge, PT Wille, AN Jones, A Davidson, J Bogdanovic, E Arts, ... Nucleic acids research 47 (3), 1523-1531, 2019 | 48 | 2019 |
Bacterial protein structures reveal phylum dependent divergence MD Shortridge, T Triplet, P Revesz, MA Griep, R Powers Computational biology and chemistry 35 (1), 24-33, 2011 | 32 | 2011 |
A multi-step NMR screen for the identification and evaluation of chemical leads for drug discovery KA Mercier, MD Shortridge, R Powers Combinatorial chemistry & high throughput screening 12 (3), 285-295, 2009 | 29 | 2009 |
PROFESS: A protein function, evolution, structure and sequence database T Triplet, MD Shortridge, MA Griep, JL Stark, R Powers, P Revesz Database 2010, baq011, 2010 | 27 | 2010 |
Structure of the RNA specialized translation initiation element that recruits eIF3 to the 5′-UTR of c-Jun MJ Walker, MD Shortridge, DD Albin, LY Cominsky, G Varani Journal of molecular biology 432 (7), 1841-1855, 2020 | 22 | 2020 |
Structure and function of Pseudomonas aeruginosa protein PA1324 (21–170) KA Mercier, JR Cort, MA Kennedy, EE Lockert, S Ni, MD Shortridge, ... Protein Science 18 (3), 606-618, 2009 | 18 | 2009 |
Efficient NMR screening approach to discover small molecule fragments binding structured RNA MD Shortridge, G Varani Acs Medicinal Chemistry Letters 12 (8), 1253-1260, 2021 | 15 | 2021 |
Correlation between protein function and ligand binding profiles MD Shortridge, M Bokemper, JC Copeland, JL Stark, R Powers Journal of proteome research 10 (5), 2538-2545, 2011 | 15 | 2011 |
Structural and functional similarity between the bacterial type III secretion system needle protein PrgI and the eukaryotic apoptosis Bcl-2 proteins MD Shortridge, R Powers PLoS One 4 (10), e7442, 2009 | 15 | 2009 |
Drug-like small molecules that inhibit expression of the oncogenic microRNA-21 MD Shortridge, B Chaubey, HJ Zhang, T Pavelitz, V Vidadala, C Tang, ... ACS chemical biology 18 (2), 237-250, 2023 | 10 | 2023 |
A Small Cyclic β‐Hairpin Peptide Mimics the Rbfox2 RNA Recognition Motif and Binds to the Precursor miRNA 20b YT Sun, MD Shortridge, G Varani ChemBioChem 20 (7), 931-939, 2019 | 8 | 2019 |
A slow dynamic RNA switch regulates processing of microRNA-21 MD Shortridge, GL Olsen, W Yang, MJ Walker, G Varani Journal of molecular biology 434 (16), 167694, 2022 | 7 | 2022 |
PROFESS: a PROtein Function, Evolution T Triplet, MD Shortridge, MA Griep, JL Stark, R Powers, P Revesz Structure and Sequence database. Database 2010, 2010 | 4 | 2010 |
The kinase inhibitor Palbociclib is a potent and specific RNA-binding molecule MD Shortridge, V Vidalala, G Varani bioRxiv, 2022.01. 20.477126, 2022 | 3 | 2022 |