| Deciphering the super relaxed state of human β-cardiac myosin and the mode of action of mavacamten from myosin molecules to muscle fibers RL Anderson, DV Trivedi, SS Sarkar, M Henze, W Ma, H Gong, ... Proceedings of the National Academy of Sciences 115 (35), E8143-E8152, 2018 | 292 | 2018 |
| Myosin head configurations in resting and contracting murine skeletal muscle W Ma, H Gong, T Irving International journal of molecular sciences 19 (9), 2643, 2018 | 55 | 2018 |
| Thick-filament extensibility in intact skeletal muscle W Ma, H Gong, B Kiss, EJ Lee, H Granzier, T Irving Biophysical journal 115 (8), 1580-1588, 2018 | 51 | 2018 |
| The super-relaxed state and length dependent activation in porcine myocardium W Ma, M Henze, RL Anderson, H Gong, FL Wong, CL Del Rio, T Irving Circulation research 129 (6), 617-630, 2021 | 47 | 2021 |
| Cardiac myosin filaments are directly regulated by calcium W Ma, S Nag, H Gong, L Qi, TC Irving Journal of General Physiology 154 (12), e202213213, 2022 | 26 | 2022 |
| Myosin dynamics during relaxation in mouse soleus muscle and modulation by 2′‐deoxy‐ATP W Ma, M Childers, J Murray, F Moussavi‐Harami, H Gong, R Weiss, ... The Journal of physiology 598 (22), 5165-5182, 2020 | 23 | 2020 |
| Structural OFF/ON transitions of myosin in relaxed porcine myocardium predict calcium-activated force W Ma, TS McMillen, MC Childers, H Gong, M Regnier, T Irving Proceedings of the National Academy of Sciences 120 (5), e2207615120, 2023 | 20 | 2023 |
| Titin force in muscle cells alters lattice order, thick and thin filament protein formation AL Hessel, W Ma, N Mazara, PE Rice, D Nissen, H Gong, M Kuehn, ... Proceedings of the National Academy of Sciences 119 (48), e2209441119, 2022 | 20 | 2022 |
| Myofibril orientation as a metric for characterizing heart disease W Ma, H Gong, V Jani, KH Lee, M Landim-Vieira, M Papadaki, JR Pinto, ... Biophysical journal 121 (4), 565-574, 2022 | 16 | 2022 |
| Triggering typical nemaline myopathy with compound heterozygous nebulin mutations reveals myofilament structural changes as pathomechanism J Lindqvist, W Ma, F Li, Y Hernandez, J Kolb, B Kiss, P Tonino, ... Nature communications 11 (1), 2699, 2020 | 14 | 2020 |
| GSK-3β localizes to the cardiac Z-disc to maintain length dependent activation MJ Stachowski-Doll, M Papadaki, TG Martin, W Ma, HM Gong, S Shao, ... Circulation research 130 (6), 871-886, 2022 | 12 | 2022 |
| Mavacamten stabilizes a folded-back sequestered super-relaxed state of β-cardiac myosin RL Anderson, DV Trivedi, SS Sarkar, M Henze, W Ma, H Gong, ... BioRxiv, 266783, 2018 | 12 | 2018 |
| Cardiac troponin T N-domain variant destabilizes the actin interface resulting in disturbed myofilament function M Landim-Vieira, W Ma, T Song, H Rastegarpouyani, H Gong, ... Proceedings of the National Academy of Sciences 120 (23), e2221244120, 2023 | 7 | 2023 |
| Thick filament activation is different in fast‐and slow‐twitch skeletal muscle HM Gong, W Ma, M Regnier, TC Irving The Journal of physiology 600 (24), 5247-5266, 2022 | 7 | 2022 |
| MgADP Promotes Myosin Head Movement toward Actin at Low [Ca2+] to Increase Force Production and Ca2+-Sensitivity of Contraction in Permeabilized Porcine … PO Awinda, W Ma, KL Turner, J Zhao, H Gong, MS Thompson, ... International Journal of Molecular Sciences 23 (23), 15084, 2022 | 4 | 2022 |
| Right ventricular sarcomere contractile depression and the role of thick filament activation in human heart failure with pulmonary hypertension V Jani, MI Aslam, AJ Fenwick, W Ma, H Gong, G Milburn, D Nissen, ... Circulation 147 (25), 1919-1932, 2023 | 3 | 2023 |
| Myosin in autoinhibited off state (s), stabilized by mavacamten, can be recruited via inotropic effectors W Ma, L Qi, M Prodanovic, HM Gong, C Zambataro, SK Gollapudi, ... Biophysical Journal 122 (3), 122a, 2023 | 3 | 2023 |
| The structural OFF and ON states of myosin can be decoupled from the biochemical super-and disordered-relaxed states VP Jani, T Song, C Gao, H Gong, S Sadayappan, DA Kass, TC Irving, ... PNAS nexus 3 (2), pgae039, 2024 | 2 | 2024 |
| The structural and functional integrities of porcine myocardium are mostly preserved by cryopreservation W Ma, KH Lee, CE Delligatti, MT Davis, Y Zheng, H Gong, JA Kirk, ... Journal of General Physiology 155 (9), e202313345, 2023 | 2 | 2023 |
| Abstract P505: Rv Sarcomeres From Lv-hfref Patients With Low Papi Have Abnormal Rv Thick Filament Structure V Jani, MI Aslam, W Ma, H Gong, A Cammarato, T Irving, DA Kass, S Hsu Circulation research 129 (Suppl_1), AP505-AP505, 2021 | 2 | 2021 |
Thomas IrvingProfessor of Biology, Illinois Institute of TechnologyПотвърден имейл адрес: iit.edu
