Pharmacology and functions of metabotropic glutamate receptors PJ Conn, JP Pin Annual review of pharmacology and toxicology 37 (1), 205-237, 1997 | 3782 | 1997 |
Metabotropic glutamate receptors: physiology, pharmacology, and disease CM Niswender, PJ Conn Annual review of pharmacology and toxicology 50 (1), 295-322, 2010 | 2240 | 2010 |
Allosteric modulators of GPCRs: a novel approach for the treatment of CNS disorders P Jeffrey Conn, A Christopoulos, CW Lindsley Nature reviews Drug discovery 8 (1), 41-54, 2009 | 1205 | 2009 |
Metabotropic glutamate receptors in brain function and pathology DD Schoepp, PJ Conn Trends in Pharmacological Sciences 14 (1), 13-20, 1993 | 1040 | 1993 |
Metabotropic glutamate receptors: from the workbench to the bedside F Nicoletti, J Bockaert, GL Collingridge, PJ Conn, F Ferraguti, ... Neuropharmacology 60 (7-8), 1017-1041, 2011 | 710 | 2011 |
Structure of a class C GPCR metabotropic glutamate receptor 1 bound to an allosteric modulator H Wu, C Wang, KJ Gregory, GW Han, HP Cho, Y Xia, CM Niswender, ... Science 344 (6179), 58-64, 2014 | 606 | 2014 |
Metabotropic glutamate receptors 1 and 5 differentially regulate CA1 pyramidal cell function G Mannaioni, MJ Marino, O Valenti, SF Traynelis, PJ Conn Journal of Neuroscience 21 (16), 5925-5934, 2001 | 530 | 2001 |
Activation of metabotropic glutamate receptor 5 has direct excitatory effects and potentiates NMDA receptor currents in neurons of the subthalamic nucleus H Awad, GW Hubert, Y Smith, AI Levey, PJ Conn Journal of neuroscience 20 (21), 7871-7879, 2000 | 509 | 2000 |
Multiple presynaptic metabotropic glutamate receptors modulate excitatory and inhibitory synaptic transmission in hippocampal area CA1 RW Gereau, PJ Conn Journal of Neuroscience 15 (10), 6879-6889, 1995 | 439 | 1995 |
Activation of metabotropic glutamate receptors as a novel approach for the treatment of schizophrenia PJ Conn, CW Lindsley, CK Jones Trends in pharmacological sciences 30 (1), 25-31, 2009 | 414 | 2009 |
Metabotropic glutamate receptors in the basal ganglia motor circuit PJ Conn, G Battaglia, MJ Marino, F Nicoletti Nature Reviews Neuroscience 6 (10), 787-798, 2005 | 390 | 2005 |
A unique serotonin receptor in choroid plexus is linked to phosphatidylinositol turnover. PJ Conn, E Sanders-Bush, BJ Hoffman, PR Hartig Proceedings of the National Academy of Sciences 83 (11), 4086-4088, 1986 | 389 | 1986 |
Molecular determinants of metabotropic glutamate receptor signaling A De Blasi, PJ Conn, JP Pin, F Nicoletti Trends in pharmacological sciences 22 (3), 114-120, 2001 | 374 | 2001 |
Fragile X mouse: strain effects of knockout phenotype and evidence suggesting deficient amygdala function W Paradee, HE Melikian, DL Rasmussen, A Kenneson, PJ Conn, ... Neuroscience 94 (1), 185-192, 1999 | 368 | 1999 |
N-desmethylclozapine, an allosteric agonist at muscarinic 1 receptor, potentiates N-methyl-D-aspartate receptor activity C Sur, PJ Mallorga, M Wittmann, MA Jacobson, D Pascarella, JB Williams, ... Proceedings of the National Academy of Sciences 100 (23), 13674-13679, 2003 | 360 | 2003 |
A novel selective positive allosteric modulator of metabotropic glutamate receptor subtype 5 has in vivo activity and antipsychotic-like effects in rat behavioral models GG Kinney, JA O'Brien, W Lemaire, M Burno, DJ Bickel, MK Clements, ... Journal of Pharmacology and Experimental Therapeutics 313 (1), 199-206, 2005 | 345 | 2005 |
Activation of the genetically defined m1 muscarinic receptor potentiates N-methyl-d-aspartate (NMDA) receptor currents in hippocampal pyramidal cells MJ Marino, ST Rouse, AI Levey, LT Potter, PJ Conn Proceedings of the National Academy of Sciences 95 (19), 11465-11470, 1998 | 330 | 1998 |
Glutamate receptors as therapeutic targets for Parkinson's disease KA Johnson, PJ Conn, CM Niswender CNS & Neurological Disorders-Drug Targets (Formerly Current Drug Targets-CNS …, 2009 | 320 | 2009 |
Subtype-selective allosteric modulators of muscarinic receptors for the treatment of CNS disorders PJ Conn, CK Jones, CW Lindsley Trends in pharmacological sciences 30 (3), 148-155, 2009 | 317 | 2009 |
Allosteric modulation of group III metabotropic glutamate receptor 4: a potential approach to Parkinson's disease treatment MJ Marino, DL Williams Jr, JA O'Brien, O Valenti, TP McDonald, ... Proceedings of the National Academy of Sciences 100 (23), 13668-13673, 2003 | 302 | 2003 |