Следене
conn pj
conn pj
Lee E. Limbird Professor, Director, Vanderbilt Center for Neuroscience Drug Discovery, Vanderbilt University
Потвърден имейл адрес: vanderbilt.edu - Начална страница
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Позовавания
Позовавания
Година
Pharmacology and functions of metabotropic glutamate receptors
PJ Conn, JP Pin
Annual review of pharmacology and toxicology 37 (1), 205-237, 1997
37821997
Metabotropic glutamate receptors: physiology, pharmacology, and disease
CM Niswender, PJ Conn
Annual review of pharmacology and toxicology 50 (1), 295-322, 2010
22402010
Allosteric modulators of GPCRs: a novel approach for the treatment of CNS disorders
P Jeffrey Conn, A Christopoulos, CW Lindsley
Nature reviews Drug discovery 8 (1), 41-54, 2009
12052009
Metabotropic glutamate receptors in brain function and pathology
DD Schoepp, PJ Conn
Trends in Pharmacological Sciences 14 (1), 13-20, 1993
10401993
Metabotropic glutamate receptors: from the workbench to the bedside
F Nicoletti, J Bockaert, GL Collingridge, PJ Conn, F Ferraguti, ...
Neuropharmacology 60 (7-8), 1017-1041, 2011
7102011
Structure of a class C GPCR metabotropic glutamate receptor 1 bound to an allosteric modulator
H Wu, C Wang, KJ Gregory, GW Han, HP Cho, Y Xia, CM Niswender, ...
Science 344 (6179), 58-64, 2014
6062014
Metabotropic glutamate receptors 1 and 5 differentially regulate CA1 pyramidal cell function
G Mannaioni, MJ Marino, O Valenti, SF Traynelis, PJ Conn
Journal of Neuroscience 21 (16), 5925-5934, 2001
5302001
Activation of metabotropic glutamate receptor 5 has direct excitatory effects and potentiates NMDA receptor currents in neurons of the subthalamic nucleus
H Awad, GW Hubert, Y Smith, AI Levey, PJ Conn
Journal of neuroscience 20 (21), 7871-7879, 2000
5092000
Multiple presynaptic metabotropic glutamate receptors modulate excitatory and inhibitory synaptic transmission in hippocampal area CA1
RW Gereau, PJ Conn
Journal of Neuroscience 15 (10), 6879-6889, 1995
4391995
Activation of metabotropic glutamate receptors as a novel approach for the treatment of schizophrenia
PJ Conn, CW Lindsley, CK Jones
Trends in pharmacological sciences 30 (1), 25-31, 2009
4142009
Metabotropic glutamate receptors in the basal ganglia motor circuit
PJ Conn, G Battaglia, MJ Marino, F Nicoletti
Nature Reviews Neuroscience 6 (10), 787-798, 2005
3902005
A unique serotonin receptor in choroid plexus is linked to phosphatidylinositol turnover.
PJ Conn, E Sanders-Bush, BJ Hoffman, PR Hartig
Proceedings of the National Academy of Sciences 83 (11), 4086-4088, 1986
3891986
Molecular determinants of metabotropic glutamate receptor signaling
A De Blasi, PJ Conn, JP Pin, F Nicoletti
Trends in pharmacological sciences 22 (3), 114-120, 2001
3742001
Fragile X mouse: strain effects of knockout phenotype and evidence suggesting deficient amygdala function
W Paradee, HE Melikian, DL Rasmussen, A Kenneson, PJ Conn, ...
Neuroscience 94 (1), 185-192, 1999
3681999
N-desmethylclozapine, an allosteric agonist at muscarinic 1 receptor, potentiates N-methyl-D-aspartate receptor activity
C Sur, PJ Mallorga, M Wittmann, MA Jacobson, D Pascarella, JB Williams, ...
Proceedings of the National Academy of Sciences 100 (23), 13674-13679, 2003
3602003
A novel selective positive allosteric modulator of metabotropic glutamate receptor subtype 5 has in vivo activity and antipsychotic-like effects in rat behavioral models
GG Kinney, JA O'Brien, W Lemaire, M Burno, DJ Bickel, MK Clements, ...
Journal of Pharmacology and Experimental Therapeutics 313 (1), 199-206, 2005
3452005
Activation of the genetically defined m1 muscarinic receptor potentiates N-methyl-d-aspartate (NMDA) receptor currents in hippocampal pyramidal cells
MJ Marino, ST Rouse, AI Levey, LT Potter, PJ Conn
Proceedings of the National Academy of Sciences 95 (19), 11465-11470, 1998
3301998
Glutamate receptors as therapeutic targets for Parkinson's disease
KA Johnson, PJ Conn, CM Niswender
CNS & Neurological Disorders-Drug Targets (Formerly Current Drug Targets-CNS …, 2009
3202009
Subtype-selective allosteric modulators of muscarinic receptors for the treatment of CNS disorders
PJ Conn, CK Jones, CW Lindsley
Trends in pharmacological sciences 30 (3), 148-155, 2009
3172009
Allosteric modulation of group III metabotropic glutamate receptor 4: a potential approach to Parkinson's disease treatment
MJ Marino, DL Williams Jr, JA O'Brien, O Valenti, TP McDonald, ...
Proceedings of the National Academy of Sciences 100 (23), 13668-13673, 2003
3022003
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