| The Concise Guide to PHARMACOLOGY 2019/20: G protein‐coupled receptors SPH Alexander, A Christopoulos, AP Davenport, E Kelly, A Mathie, ... British journal of pharmacology 176, S21-S141, 2019 | 781 | 2019 |
| Structure of a class C GPCR metabotropic glutamate receptor 1 bound to an allosteric modulator H Wu, C Wang, KJ Gregory, GW Han, HP Cho, Y Xia, CM Niswender, ... Science 344 (6179), 58-64, 2014 | 606 | 2014 |
| The Concise Guide to PHARMACOLOGY 2021/22: G protein‐coupled receptors SPH Alexander, A Christopoulos, AP Davenport, E Kelly, A Mathie, ... British journal of pharmacology 178, S27-S156, 2021 | 482 | 2021 |
| The concise guide to pharmacology 2017/18: overview SPH Alexander, E Kelly, NV Marrion, JA Peters, E Faccenda, SD Harding, ... British journal of pharmacology 174, S1-S16, 2017 | 313 | 2017 |
| A Novel Mechanism of G Protein-coupled Receptor Functional Selectivity: MUSCARINIC PARTIAL AGONIST McN-A-343 AS A BITOPIC ORTHOSTERIC/ALLOSTERIC LIGAND∗ C Valant, KJ Gregory, NE Hall, PJ Scammells, MJ Lew, PM Sexton, ... Journal of Biological Chemistry 283 (43), 29312-29321, 2008 | 201 | 2008 |
| Critical role for the second extracellular loop in the binding of both orthosteric and allosteric G protein-coupled receptor ligands VA Avlani, KJ Gregory, CJ Morton, MW Parker, PM Sexton, ... Journal of Biological Chemistry 282 (35), 25677-25686, 2007 | 187 | 2007 |
| Practical strategies and concepts in GPCR allosteric modulator discovery: recent advances with metabotropic glutamate receptors CW Lindsley, KA Emmitte, CR Hopkins, TM Bridges, KJ Gregory, ... Chemical reviews 116 (11), 6707-6741, 2016 | 181 | 2016 |
| Identification of orthosteric and allosteric site mutations in M2 muscarinic acetylcholine receptors that contribute to ligand-selective signaling bias KJ Gregory, NE Hall, AB Tobin, PM Sexton, A Christopoulos Journal of Biological Chemistry 285 (10), 7459-7474, 2010 | 179 | 2010 |
| Allosteric modulation of muscarinic acetylcholine receptors KJ Gregory, PM Sexton, A Christopoulos Current neuropharmacology 5 (3), 157-167, 2007 | 149 | 2007 |
| Allosteric modulation of metabotropic glutamate receptors: structural insights and therapeutic potential KJ Gregory, EN Dong, J Meiler, PJ Conn Neuropharmacology 60 (1), 66-81, 2011 | 141 | 2011 |
| Selective actions of novel allosteric modulators reveal functional heteromers of metabotropic glutamate receptors in the CNS S Yin, MJ Noetzel, KA Johnson, R Zamorano, N Jalan-Sakrikar, ... Journal of Neuroscience 34 (1), 79-94, 2014 | 136 | 2014 |
| Biased mGlu5-positive allosteric modulators provide in vivo efficacy without potentiating mGlu5 modulation of NMDAR currents JM Rook, Z Xiang, X Lv, A Ghoshal, JW Dickerson, TM Bridges, ... Neuron 86 (4), 1029-1040, 2015 | 133 | 2015 |
| The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors SPH Alexander, A Christopoulos, AP Davenport, E Kelly, AA Mathie, ... British Journal of Pharmacology 180, S23-S144, 2023 | 125 | 2023 |
| Characterization of serotonin 5‐HT2C receptor signaling to extracellular signal‐regulated kinases 1 and 2 TD Werry, KJ Gregory, PM Sexton, A Christopoulos Journal of neurochemistry 93 (6), 1603-1615, 2005 | 118 | 2005 |
| Towards a structural understanding of allosteric drugs at the human calcium-sensing receptor K Leach, KJ Gregory, I Kufareva, E Khajehali, AE Cook, R Abagyan, ... Cell research 26 (5), 574-592, 2016 | 111 | 2016 |
| Unique signaling profiles of positive allosteric modulators of metabotropic glutamate receptor subtype 5 determine differences in in vivo activity JM Rook, MJ Noetzel, WA Pouliot, TM Bridges, PN Vinson, HP Cho, ... Biological psychiatry 73 (6), 501-509, 2013 | 107 | 2013 |
| Biased allosteric modulation at the CaS receptor engendered by structurally diverse calcimimetics AE Cook, SN Mistry, KJ Gregory, SGB Furness, PM Sexton, PJ Scammells, ... British journal of pharmacology 172 (1), 185-200, 2015 | 88 | 2015 |
| A novel metabotropic glutamate receptor 5 positive allosteric modulator acts at a unique site and confers stimulus bias to mGlu5 signaling MJ Noetzel, KJ Gregory, PN Vinson, JT Manka, SR Stauffer, CW Lindsley, ... Molecular pharmacology 83 (4), 835-847, 2013 | 82 | 2013 |
| Probing the metabotropic glutamate receptor 5 (mGlu5) positive allosteric modulator (PAM) binding pocket: discovery of point mutations that engender a “molecular switch” in PAM … KJ Gregory, ED Nguyen, SD Reiff, EF Squire, SR Stauffer, CW Lindsley, ... Molecular pharmacology 83 (5), 991-1006, 2013 | 81 | 2013 |
| Discovery of a Novel Chemical Class of mGlu5 Allosteric Ligands with Distinct Modes of Pharmacology AS Hammond, AL Rodriguez, SD Townsend, CM Niswender, KJ Gregory, ... ACS chemical neuroscience 1 (10), 702-716, 2010 | 81 | 2010 |
Jens MeilerVanderbilt University & University LeipzigПотвърден имейл адрес: meilerlab.org
