Rohit V. Pappu
Rohit V. Pappu
Gene K. Beare Distinguished Professor of Biomedical Engineering, Washington University in St. Louis
Verified email at - Homepage
Cited by
Cited by
Classification of intrinsically disordered regions and proteins
R Van Der Lee, M Buljan, B Lang, RJ Weatheritt, GW Daughdrill, ...
Chemical reviews 114 (13), 6589-6631, 2014
Coexisting liquid phases underlie nucleolar subcompartments
M Feric, N Vaidya, TS Harmon, DM Mitrea, L Zhu, TM Richardson, ...
Cell 165 (7), 1686-1697, 2016
A molecular grammar governing the driving forces for phase separation of prion-like RNA binding proteins
J Wang, JM Choi, AS Holehouse, HO Lee, X Zhang, M Jahnel, ...
Cell 174 (3), 688-699. e16, 2018
Polymer physics of intracellular phase transitions
CP Brangwynne, P Tompa, RV Pappu
Nature Physics 11 (11), 899-904, 2015
Conformations of intrinsically disordered proteins are influenced by linear sequence distributions of oppositely charged residues
RK Das, RV Pappu
Proceedings of the National Academy of Sciences 110 (33), 13392-13397, 2013
Sequence determinants of intracellular phase separation by complex coacervation of a disordered protein
CW Pak, M Kosno, AS Holehouse, SB Padrick, A Mittal, R Ali, AA Yunus, ...
Molecular cell 63 (1), 72-85, 2016
Phase separation of a yeast prion protein promotes cellular fitness
TM Franzmann, M Jahnel, A Pozniakovsky, J Mahamid, AS Holehouse, ...
Science 359 (6371), eaao5654, 2018
Net charge per residue modulates conformational ensembles of intrinsically disordered proteins
AH Mao, SL Crick, A Vitalis, CL Chicoine, RV Pappu
Proceedings of the National Academy of Sciences 107 (18), 8183-8188, 2010
Valence and patterning of aromatic residues determine the phase behavior of prion-like domains
EW Martin, AS Holehouse, I Peran, M Farag, JJ Incicco, A Bremer, ...
Science 367 (6478), 694-699, 2020
RNA-induced conformational switching and clustering of G3BP drive stress granule assembly by condensation
J Guillén-Boixet, A Kopach, AS Holehouse, S Wittmann, M Jahnel, ...
Cell 181 (2), 346-361. e17, 2020
Intrinsically disordered linkers determine the interplay between phase separation and gelation in multivalent proteins
TS Harmon, AS Holehouse, MK Rosen, RV Pappu
elife 6, e30294, 2017
Amyloid seeds formed by cellular uptake, concentration, and aggregation of the amyloid-beta peptide
X Hu, SL Crick, G Bu, C Frieden, RV Pappu, JM Lee
Proceedings of the National Academy of Sciences 106 (48), 20324-20329, 2009
Physical principles underlying the complex biology of intracellular phase transitions
JM Choi, AS Holehouse, RV Pappu
Annual review of biophysics 49, 107-133, 2020
Phase behaviour of disordered proteins underlying low density and high permeability of liquid organelles
MT Wei, S Elbaum-Garfinkle, AS Holehouse, CCH Chen, M Feric, ...
Nature chemistry 9 (11), 1118-1125, 2017
The Flory isolated-pair hypothesis is not valid for polypeptide chains: implications for protein folding
RV Pappu, R Srinivasan, GD Rose
Proceedings of the National Academy of Sciences 97 (23), 12565-12570, 2000
Relating sequence encoded information to form and function of intrinsically disordered proteins
RK Das, KM Ruff, RV Pappu
Current opinion in structural biology 32, 102-112, 2015
Fluorescence correlation spectroscopy shows that monomeric polyglutamine molecules form collapsed structures in aqueous solutions
SL Crick, M Jayaraman, C Frieden, R Wetzel, RV Pappu
Proceedings of the National Academy of Sciences 103 (45), 16764-16769, 2006
Analysis and application of potential energy smoothing and search methods for global optimization
RV Pappu, RK Hart, JW Ponder
The Journal of Physical Chemistry B 102 (48), 9725-9742, 1998
Spontaneous driving forces give rise to protein− RNA condensates with coexisting phases and complex material properties
S Boeynaems, AS Holehouse, V Weinhardt, D Kovacs, J Van Lindt, ...
Proceedings of the National Academy of Sciences 116 (16), 7889-7898, 2019
ABSINTH: a new continuum solvation model for simulations of polypeptides in aqueous solutions
A Vitalis, RV Pappu
Journal of computational chemistry 30 (5), 673-699, 2009
The system can't perform the operation now. Try again later.
Articles 1–20