Rohit V. Pappu
Rohit V. Pappu
Gene K. Beare Distinguished Professor of Biomedical Engineering, Washington University in St. Louis
Потвърден имейл адрес: wustl.edu - Начална страница
Classification of intrinsically disordered regions and proteins
R Van Der Lee, M Buljan, B Lang, RJ Weatheritt, GW Daughdrill, ...
Chemical reviews 114 (13), 6589-6631, 2014
Coexisting liquid phases underlie nucleolar subcompartments
M Feric, N Vaidya, TS Harmon, DM Mitrea, L Zhu, TM Richardson, ...
Cell 165 (7), 1686-1697, 2016
A molecular grammar governing the driving forces for phase separation of prion-like RNA binding proteins
J Wang, JM Choi, AS Holehouse, HO Lee, X Zhang, M Jahnel, ...
Cell 174 (3), 688-699. e16, 2018
Polymer physics of intracellular phase transitions
CP Brangwynne, P Tompa, RV Pappu
Nature Physics 11 (11), 899-904, 2015
Conformations of intrinsically disordered proteins are influenced by linear sequence distributions of oppositely charged residues
RK Das, RV Pappu
Proceedings of the National Academy of Sciences 110 (33), 13392-13397, 2013
Sequence determinants of intracellular phase separation by complex coacervation of a disordered protein
CW Pak, M Kosno, AS Holehouse, SB Padrick, A Mittal, R Ali, AA Yunus, ...
Molecular cell 63 (1), 72-85, 2016
Phase separation of a yeast prion protein promotes cellular fitness
TM Franzmann, M Jahnel, A Pozniakovsky, J Mahamid, AS Holehouse, ...
Science 359 (6371), eaao5654, 2018
Net charge per residue modulates conformational ensembles of intrinsically disordered proteins
AH Mao, SL Crick, A Vitalis, CL Chicoine, RV Pappu
Proceedings of the National Academy of Sciences 107 (18), 8183-8188, 2010
Amyloid seeds formed by cellular uptake, concentration, and aggregation of the amyloid-beta peptide
X Hu, SL Crick, G Bu, C Frieden, RV Pappu, JM Lee
Proceedings of the National Academy of Sciences 106 (48), 20324-20329, 2009
Valence and patterning of aromatic residues determine the phase behavior of prion-like domains
EW Martin, AS Holehouse, I Peran, M Farag, JJ Incicco, A Bremer, ...
Science 367 (6478), 694-699, 2020
Intrinsically disordered linkers determine the interplay between phase separation and gelation in multivalent proteins
TS Harmon, AS Holehouse, MK Rosen, RV Pappu
elife 6, e30294, 2017
RNA-induced conformational switching and clustering of G3BP drive stress granule assembly by condensation
J Guillén-Boixet, A Kopach, AS Holehouse, S Wittmann, M Jahnel, ...
Cell 181 (2), 346-361. e17, 2020
Phase behaviour of disordered proteins underlying low density and high permeability of liquid organelles
MT Wei, S Elbaum-Garfinkle, AS Holehouse, CCH Chen, M Feric, ...
Nature chemistry 9 (11), 1118-1125, 2017
Physical principles underlying the complex biology of intracellular phase transitions
JM Choi, AS Holehouse, RV Pappu
Annual review of biophysics 49, 107-133, 2020
The Flory isolated-pair hypothesis is not valid for polypeptide chains: implications for protein folding
RV Pappu, R Srinivasan, GD Rose
Proceedings of the National Academy of Sciences 97 (23), 12565-12570, 2000
Fluorescence correlation spectroscopy shows that monomeric polyglutamine molecules form collapsed structures in aqueous solutions
SL Crick, M Jayaraman, C Frieden, R Wetzel, RV Pappu
Proceedings of the National Academy of Sciences 103 (45), 16764-16769, 2006
Analysis and application of potential energy smoothing and search methods for global optimization
RV Pappu, RK Hart, JW Ponder
The Journal of Physical Chemistry B 102 (48), 9725-9742, 1998
Relating sequence encoded information to form and function of intrinsically disordered proteins
RK Das, KM Ruff, RV Pappu
Current opinion in structural biology 32, 102-112, 2015
ABSINTH: a new continuum solvation model for simulations of polypeptides in aqueous solutions
A Vitalis, RV Pappu
Journal of computational chemistry 30 (5), 673-699, 2009
Spontaneous driving forces give rise to protein− RNA condensates with coexisting phases and complex material properties
S Boeynaems, AS Holehouse, V Weinhardt, D Kovacs, J Van Lindt, ...
Proceedings of the National Academy of Sciences 116 (16), 7889-7898, 2019
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