Automated structure-and sequence-based design of proteins for high bacterial expression and stability A Goldenzweig, M Goldsmith, SE Hill, O Gertman, P Laurino, Y Ashani, ... Molecular cell 63 (2), 337-346, 2016 | 532 | 2016 |
Principles of protein stability and their application in computational design A Goldenzweig, SJ Fleishman Annual review of biochemistry 87, 105-129, 2018 | 270 | 2018 |
One-step design of a stable variant of the malaria invasion protein RH5 for use as a vaccine immunogen I Campeotto, A Goldenzweig, J Davey, L Barfod, JM Marshall, SE Silk, ... Proceedings of the National Academy of Sciences 114 (5), 998-1002, 2017 | 96 | 2017 |
Overcoming an optimization plateau in the directed evolution of highly efficient nerve agent bioscavengers M Goldsmith, N Aggarwal, Y Ashani, H Jubran, PJ Greisen, S Ovchinnikov, ... Protein Engineering, Design and Selection 30 (4), 333-345, 2017 | 78 | 2017 |
PROSS 2: a new server for the design of stable and highly expressed protein variants JJ Weinstein, A Goldenzweig, SY Hoch, SJ Fleishman Bioinformatics 37 (1), 123-125, 2021 | 55 | 2021 |
Community-wide experimental evaluation of the PROSS stability-design method Y Peleg, R Vincentelli, BM Collins, KE Chen, EK Livingstone, ... Journal of molecular biology 433 (13), 166964, 2021 | 48 | 2021 |
Local energetic frustration affects the dependence of green fluorescent protein folding on the chaperonin GroEL B Bandyopadhyay, A Goldenzweig, T Unger, O Adato, SJ Fleishman, ... Journal of Biological Chemistry 292 (50), 20583-20591, 2017 | 27 | 2017 |
Manipulating the folding landscape of a multidomain protein R Kantaev, I Riven, A Goldenzweig, Y Barak, O Dym, Y Peleg, S Albeck, ... The Journal of Physical Chemistry B 122 (49), 11030-11038, 2018 | 25 | 2018 |
One-step sequence and structure-guided optimization of HIV-1 envelope gp140 SK Malladi, D Schreiber, I Pramanick, MA Sridevi, A Goldenzweig, S Dutta, ... Current research in structural biology 2, 45-55, 2020 | 13 | 2020 |
Isolated phosphotriesterase polypeptides, polynucleotides encoding same and uses thereof in treating or preventing organophosphate exposure associated damage DS Tawfik, H Leader, Y Ashani, I Cherny, M Goldsmith, SD KHARE, ... US Patent 10,688,330, 2020 | | 2020 |
Stable proteins and methods for designing same S Fleishman, A Goldenzweig, DS Tawfik US Patent App. 16/672,601, 2020 | | 2020 |
Thermostable variants of p. falciparum pfrh5 which can be produced in bacterial cells SJ Draper, I Campeotto, MK Higgins, S Fleishman, A Goldenzweig US Patent App. 16/331,863, 2019 | | 2019 |