Следене
Ronan Chaligne
Ronan Chaligne
Потвърден имейл адрес: mskcc.org
Заглавие
Позовавания
Позовавания
Година
Integrating genetic and non-genetic determinants of cancer evolution by single-cell multi-omics
AS Nam, R Chaligne, DA Landau
Nature Reviews Genetics 22 (1), 3-18, 2021
2862021
Somatic mutations and cell identity linked by Genotyping of Transcriptomes
AS Nam, KT Kim, R Chaligne, F Izzo, C Ang, J Taylor, RM Myers, ...
Nature 571 (7765), 355-360, 2019
2462019
Epigenetic evolution and lineage histories of chronic lymphocytic leukaemia
F Gaiti, R Chaligne, H Gu, RM Brand, S Kothen-Hill, RC Schulman, ...
Nature 569 (7757), 576-580, 2019
2222019
DNA methylation disruption reshapes the hematopoietic differentiation landscape
F Izzo, SC Lee, A Poran, R Chaligne, F Gaiti, B Gross, RR Murali, ...
Nature genetics 52 (4), 378-387, 2020
1962020
X-chromosome inactivation in development and cancer
R Chaligné, E Heard
FEBS letters 588 (15), 2514-2522, 2014
1562014
New mutations of MPL in primitive myelofibrosis: only the MPL W515 mutations promote a G1/S-phase transition
R Chaligné, C Tonetti, R Besancenot, L Roy, C Marty, P Mossuz, ...
Leukemia 22 (8), 1557-1566, 2008
1492008
The inactive X chromosome is epigenetically unstable and transcriptionally labile in breast cancer
R Chaligné, T Popova, MA Mendoza-Parra, MAM Saleem, D Gentien, ...
Genome research 25 (4), 488-503, 2015
1472015
Evidence for MPL W515L/K mutations in hematopoietic stem cells in primitive myelofibrosis
R Chaligné, C James, C Tonetti, R Besancenot, JP Le Couédic, F Fava, ...
Blood 110 (10), 3735-3743, 2007
1272007
The hematopoietic stem cell compartment of JAK2V617F-positive myeloproliferative disorders is a reflection of disease heterogeneity
C James, F Mazurier, S Dupont, R Chaligne, I Lamrissi-Garcia, M Tulliez, ...
Blood 112 (6), 2429-2438, 2008
1242008
Epigenetic encoding, heritability and plasticity of glioma transcriptional cell states
R Chaligne, F Gaiti, D Silverbush, JS Schiffman, HR Weisman, L Kluegel, ...
Nature genetics 53 (10), 1469-1479, 2021
1172021
A senescence-like cell-cycle arrest occurs during megakaryocytic maturation: implications for physiological and pathological megakaryocytic proliferation
R Besancenot, R Chaligné, C Tonetti, F Pasquier, C Marty, Y Lécluse, ...
PLoS biology 8 (9), e1000476, 2010
1172010
Lineage plasticity in prostate cancer depends on JAK/STAT inflammatory signaling
JM Chan, S Zaidi, JR Love, JL Zhao, M Setty, KM Wadosky, A Gopalan, ...
Science 377 (6611), 1180-1191, 2022
1102022
Induction of myeloproliferative disorder and myelofibrosis by thrombopoietin receptor W515 mutants is mediated by cytosolic tyrosine 112 of the receptor
C Pecquet, J Staerk, R Chaligné, V Goss, KA Lee, X Zhang, J Rush, ...
Blood 115 (5), 1037-1048, 2010
962010
Corrupted coordination of epigenetic modifications leads to diverging chromatin states and transcriptional heterogeneity in CLL
A Pastore, F Gaiti, SX Lu, RM Brand, S Kulm, R Chaligne, H Gu, ...
Nature communications 10 (1), 1874, 2019
692019
Single-cell multi-omics of human clonal hematopoiesis reveals that DNMT3A R882 mutations perturb early progenitor states through selective hypomethylation
AS Nam, N Dusaj, F Izzo, R Murali, RM Myers, TH Mouhieddine, J Sotelo, ...
Nature genetics 54 (10), 1514-1526, 2022
672022
Proteasome inhibitor bortezomib impairs both myelofibrosis and osteosclerosis induced by high thrombopoietin levels in mice
O Wagner-Ballon, DF Pisani, T Gastinne, M Tulliez, R Chaligné, C Lacout, ...
Blood 110 (1), 345-353, 2007
602007
Anatomic position determines oncogenic specificity in melanoma
JM Weiss, MV Hunter, NM Cruz, A Baggiolini, M Tagore, Y Ma, S Misale, ...
Nature 604 (7905), 354-361, 2022
592022
Discovery of candidate DNA methylation cancer driver genes
H Pan, L Renaud, R Chaligne, J Bloehdorn, E Tausch, D Mertens, ...
Cancer discovery 11 (9), 2266-2281, 2021
462021
Epigenetic plasticity cooperates with cell-cell interactions to direct pancreatic tumorigenesis
C Burdziak, D Alonso-Curbelo, T Walle, J Reyes, FM Barriga, D Haviv, ...
Science 380 (6645), eadd5327, 2023
402023
Smart-RRBS for single-cell methylome and transcriptome analysis
H Gu, AT Raman, X Wang, F Gaiti, R Chaligne, AW Mohammad, ...
Nature protocols 16 (8), 4004-4030, 2021
402021
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