Paul DeCaen
Paul DeCaen
Northwestern University, Harvard University, HHMI,
Verified email at
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Crystal structure of an orthologue of the NaChBac voltage-gated sodium channel
X Zhang, W Ren, P DeCaen, C Yan, X Tao, L Tang, J Wang, K Hasegawa, ...
Nature 486 (7401), 130-134, 2012
Primary cilia are specialized calcium signalling organelles
M Delling, PG DeCaen, JF Doerner, S Febvay, DE Clapham
Nature 504 (7479), 311-314, 2013
Direct recording and molecular identification of the calcium channel of primary cilia
PG DeCaen, M Delling, TN Vien, DE Clapham
Nature 504 (7479), 315-318, 2013
Structural basis for gating charge movement in the voltage sensor of a sodium channel
V Yarov-Yarovoy, PG DeCaen, RE Westenbroek, CY Pan, T Scheuer, ...
Proceedings of the National Academy of Sciences 109 (2), E93-E102, 2012
The structure of the polycystic kidney disease channel PKD2 in lipid nanodiscs
PS Shen, X Yang, PG DeCaen, X Liu, D Bulkley, DE Clapham, E Cao
Cell 167 (3), 763-773. e11, 2016
Sequential formation of ion pairs during activation of a sodium channel voltage sensor
PG DeCaen, V Yarov-Yarovoy, EM Sharp, T Scheuer, WA Catterall
Proceedings of the National Academy of Sciences 106 (52), 22498-22503, 2009
Molecular dynamics of ion transport through the open conformation of a bacterial voltage-gated sodium channel
MB Ulmschneider, C Bagnéris, EC McCusker, PG DeCaen, M Delling, ...
Proceedings of the National Academy of Sciences 110 (16), 6364-6369, 2013
Prokaryotic NavMs channel as a structural and functional model for eukaryotic sodium channel antagonism
C Bagnéris, PG DeCaen, CE Naylor, DC Pryde, I Nobeli, DE Clapham, ...
Proceedings of the National Academy of Sciences 111 (23), 8428-8433, 2014
Disulfide locking a sodium channel voltage sensor reveals ion pair formation during activation
PG DeCaen, V Yarov-Yarovoy, Y Zhao, T Scheuer, WA Catterall
Proceedings of the National Academy of Sciences 105 (39), 15142-15147, 2008
The complete structure of an activated open sodium channel
A Sula, J Booker, LCT Ng, CE Naylor, PG DeCaen, BA Wallace
Nature communications 8 (1), 1-9, 2017
Polycystin-2 is an essential ion channel subunit in the primary cilium of the renal collecting duct epithelium
X Liu, T Vien, J Duan, SH Sheu, PG DeCaen, DE Clapham
Elife 7, 2018
Molecular basis of ion permeability in a voltage‐gated sodium channel
CE Naylor, C Bagnéris, PG DeCaen, A Sula, A Scaglione, DE Clapham, ...
The EMBO journal 35 (8), 820-830, 2016
Gating charge interactions with the S1 segment during activation of a Na+ channel voltage sensor
PG DeCaen, V Yarov-Yarovoy, T Scheuer, WA Catterall
Proceedings of the National Academy of Sciences 108 (46), 18825-18830, 2011
TRPM7 senses oxidative stress to release Zn2+ from unique intracellular vesicles
SA Abiria, G Krapivinsky, R Sah, AG Santa-Cruz, D Chaudhuri, J Zhang, ...
Proceedings of the National Academy of Sciences 114 (30), E6079-E6088, 2017
Role of the C-terminal domain in the structure and function of tetrameric sodium channels
C Bagnéris, PG DeCaen, BA Hall, CE Naylor, DE Clapham, CWM Kay, ...
Nature communications 4 (1), 1-10, 2013
Atypical calcium regulation of the PKD2-L1 polycystin ion channel
PG DeCaen, X Liu, S Abiria, DE Clapham
Elife 5, e13413, 2016
Analysis of the selectivity filter of the voltage-gated sodium channel NavRh
X Zhang, M Xia, Y Li, H Liu, X Jiang, W Ren, J Wu, P DeCaen, F Yu, ...
Cell research 23 (3), 409-422, 2013
Progress in ciliary ion channel physiology
JL Pablo, PG DeCaen, DE Clapham
Journal of General Physiology 149 (1), 37-47, 2017
Ionic selectivity and thermal adaptations within the voltage-gated sodium channel family of alkaliphilic Bacillus
PG DeCaen, Y Takahashi, TA Krulwich, M Ito, DE Clapham
Elife 3, e04387, 2014
Influence of ionic plasticizers on the processing and viscosity of starch melts
P Decaen, A Rolland-Sabaté, G Colomines, S Guilois, D Lourdin, ...
Carbohydrate polymers 230, 115591, 2020
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Articles 1–20