| Antimicrobial resistance in Neisseria gonorrhoeae in the 21st century: past, evolution, and future M Unemo, WM Shafer Clinical microbiology reviews 27 (3), 587-613, 2014 | 1029 | 2014 |
| Degradation of Human Antimicrobial Peptide LL-37 by Staphylococcus aureus-Derived Proteinases M Sieprawska-Lupa, P Mydel, K Krawczyk, K Wójcik, M Puklo, B Lupa, ... Antimicrobial agents and chemotherapy 48 (12), 4673-4679, 2004 | 665 | 2004 |
| Modulation of Neisseria gonorrhoeae susceptibility to vertebrate antibacterial peptides due to a member of the resistance/nodulation/division efflux pump family WM Shafer, XD Qu, AJ Waring, RI Lehrer Proceedings of the National Academy of Sciences 95 (4), 1829-1833, 1998 | 481 | 1998 |
| Resistance of Neisseria gonorrhoeae to antimicrobial hydrophobic agents is modulated by the mtrRCDE efflux system KE Hagman, W Pan, BG Spratt, JT Balthazar, RC Judd, WM Shafer Microbiology 141 (3), 611-622, 1995 | 467 | 1995 |
| Cationic Antimicrobial Peptide Resistance in Neisseria meningitidis YL Tzeng, KD Ambrose, S Zughaier, X Zhou, YK Miller, WM Shafer, ... Journal of bacteriology 187 (15), 5387-5396, 2005 | 281 | 2005 |
| Antibiotic resistance in Neisseria gonorrhoeae: origin, evolution, and lessons learned for the future M Unemo, WM Shafer Annals of the New York Academy of Sciences 1230 (1), E19-E28, 2011 | 272 | 2011 |
| Cationic antimicrobial proteins isolated from human neutrophil granulocytes in the presence of diisopropyl fluorophosphate. WM Shafer, LE Martin, JK Spitznagel Infection and immunity 45 (1), 29, 1984 | 270 | 1984 |
| Transcriptional control of the mtr efflux system of Neisseria gonorrhoeae KE Hagman, WM Shafer Journal of bacteriology 177 (14), 4162-4165, 1995 | 231 | 1995 |
| Clinically relevant mutations that cause derepression of the Neisseria gonorrhoeae MtrC‐MtrD‐MtrE Efflux pump system confer different levels of antimicrobial resistance and … DM Warner, WM Shafer, AE Jerse Molecular microbiology 70 (2), 462-478, 2008 | 230 | 2008 |
| A gonococcal efflux pump system enhances bacterial survival in a female mouse model of genital tract infection AE Jerse, ND Sharma, AN Simms, ET Crow, LA Snyder, WM Shafer Infection and immunity 71 (10), 5576-5582, 2003 | 228 | 2003 |
| Antimicrobial Resistance Expressed by Neisseria gonorrhoeae: A Major Global Public Health Problem in the 21st Century M Unemo, CD Rio, WM Shafer Emerging Infections 10, 213-237, 2016 | 226 | 2016 |
| Overexpression of the MtrC-MtrD-MtrE efflux pump due to an mtrR mutation is required for chromosomally mediated penicillin resistance in Neisseria gonorrhoeae WL Veal, RA Nicholas, WM Shafer Journal of bacteriology 184 (20), 5619-5624, 2002 | 209 | 2002 |
| The farAB‐encoded efflux pump mediates resistance of gonococci to long‐chained antibacterial fatty acids EH Lee, WM Shafer Molecular microbiology 33 (4), 839-845, 1999 | 195 | 1999 |
| CAP37, a human neutrophil-derived chemotactic factor with monocyte specific activity. HA Pereira, WM Shafer, J Pohl, LE Martin, JK Spitznagel The Journal of clinical investigation 85 (5), 1468-1476, 1990 | 193 | 1990 |
| Decreased Azithromycin Susceptibility ofNeisseria gonorrhoeae Due to mtrRMutations L Zarantonelli, G Borthagaray, EH Lee, WM Shafer Antimicrobial agents and chemotherapy 43 (10), 2468-2472, 1999 | 186 | 1999 |
| The NorM Efflux Pump of Neisseria gonorrhoeae and Neisseria meningitidis Recognizes Antimicrobial Cationic Compounds C Rouquette-Loughlin, SA Dunham, M Kuhn, JT Balthazar, WM Shafer Journal of bacteriology 185 (3), 1101-1106, 2003 | 169 | 2003 |
| The MtrD protein of Neisseria gonorrhoeae is a member of the resistance/nodulation/division protein family constituting part of an efflux system KE Hagman, CE Lucas, JT Balthazar, L Snyder, M Nilles, RC Judd, ... Microbiology 143 (7), 2117-2125, 1997 | 160 | 1997 |
| Genetics of staphylococcal enterotoxin B in methicillin-resistant isolates of Staphylococcus aureus WM Shafer, JJ Iandolo Infection and Immunity 25 (3), 902-911, 1979 | 159 | 1979 |
| Multidrug-resistant gonorrhea: A research and development roadmap to discover new medicines E Alirol, TE Wi, M Bala, ML Bazzo, XS Chen, C Deal, JAR Dillon, ... PLoS medicine 14 (7), e1002366, 2017 | 157 | 2017 |
| Regulation of the MtrC-MtrD-MtrE Efflux-Pump System Modulates the In Vivo Fitness of Neisseria gonorrhoeae DM Warner, JP Folster, WM Shafer, AE Jerse Journal of Infectious Diseases 196 (12), 1804-1812, 2007 | 150 | 2007 |
