William M. Shafer
William M. Shafer
Professor of Microbiology and Immunology, Emory University School of Medicine
Потвърден имейл адрес: emory.edu
Antimicrobial resistance in Neisseria gonorrhoeae in the 21st century: past, evolution, and future
M Unemo, WM Shafer
Clinical microbiology reviews 27 (3), 587-613, 2014
Degradation of Human Antimicrobial Peptide LL-37 by Staphylococcus aureus-Derived Proteinases
M Sieprawska-Lupa, P Mydel, K Krawczyk, K Wójcik, M Puklo, B Lupa, ...
Antimicrobial agents and chemotherapy 48 (12), 4673-4679, 2004
Modulation of Neisseria gonorrhoeae susceptibility to vertebrate antibacterial peptides due to a member of the resistance/nodulation/division efflux pump family
WM Shafer, XD Qu, AJ Waring, RI Lehrer
Proceedings of the National Academy of Sciences 95 (4), 1829-1833, 1998
Resistance of Neisseria gonorrhoeae to antimicrobial hydrophobic agents is modulated by the mtrRCDE efflux system
KE Hagman, W Pan, BG Spratt, JT Balthazar, RC Judd, WM Shafer
Microbiology 141 (3), 611-622, 1995
Antibiotic resistance in Neisseria gonorrhoeae: origin, evolution, and lessons learned for the future
M Unemo, WM Shafer
Annals of the New York Academy of Sciences 1230 (1), E19-E28, 2011
Cationic Antimicrobial Peptide Resistance in Neisseria meningitidis
YL Tzeng, KD Ambrose, S Zughaier, X Zhou, YK Miller, WM Shafer, ...
Journal of bacteriology 187 (15), 5387-5396, 2005
Cationic antimicrobial proteins isolated from human neutrophil granulocytes in the presence of diisopropyl fluorophosphate
WM Shafer, LE Martin, JK Spitznagel
Infection and immunity 45 (1), 29-35, 1984
Antimicrobial Resistance Expressed by Neisseria gonorrhoeae: A Major Global Public Health Problem in the 21st Century
M Unemo, CD Rio, WM Shafer
Emerging Infections 10, 213-237, 2016
Clinically relevant mutations that cause derepression of the Neisseria gonorrhoeae MtrC‐MtrD‐MtrE Efflux pump system confer different levels of antimicrobial resistance and …
DM Warner, WM Shafer, AE Jerse
Molecular microbiology 70 (2), 462-478, 2008
A gonococcal efflux pump system enhances bacterial survival in a female mouse model of genital tract infection
AE Jerse, ND Sharma, AN Simms, ET Crow, LA Snyder, WM Shafer
Infection and immunity 71 (10), 5576-5582, 2003
Transcriptional control of the mtr efflux system of Neisseria gonorrhoeae
KE Hagman, WM Shafer
Journal of bacteriology 177 (14), 4162-4165, 1995
Overexpression of the MtrC-MtrD-MtrE efflux pump due to an mtrR mutation is required for chromosomally mediated penicillin resistance in Neisseria gonorrhoeae
WL Veal, RA Nicholas, WM Shafer
Journal of bacteriology 184 (20), 5619-5624, 2002
CAP37, a human neutrophil-derived chemotactic factor with monocyte specific activity.
HA Pereira, WM Shafer, J Pohl, LE Martin, JK Spitznagel
The Journal of clinical investigation 85 (5), 1468-1476, 1990
The farAB‐encoded efflux pump mediates resistance of gonococci to long‐chained antibacterial fatty acids
EH Lee, WM Shafer
Molecular microbiology 33 (4), 839-845, 1999
Decreased Azithromycin Susceptibility ofNeisseria gonorrhoeae Due to mtrRMutations
L Zarantonelli, G Borthagaray, EH Lee, WM Shafer
Antimicrobial agents and chemotherapy 43 (10), 2468-2472, 1999
Neisseria gonorrhoeae: Drug Resistance, Mouse Models, and Vaccine Development
PA Rice, WM Shafer, S Ram, AE Jerse
Annual review of microbiology 71, 665-686, 2017
The NorM Efflux Pump of Neisseria gonorrhoeae and Neisseria meningitidis Recognizes Antimicrobial Cationic Compounds
C Rouquette-Loughlin, SA Dunham, M Kuhn, JT Balthazar, WM Shafer
Journal of bacteriology 185 (3), 1101-1106, 2003
Multidrug-resistant gonorrhea: A research and development roadmap to discover new medicines
E Alirol, TE Wi, M Bala, ML Bazzo, XS Chen, C Deal, JAR Dillon, ...
PLoS medicine 14 (7), e1002366, 2017
Genetics of staphylococcal enterotoxin B in methicillin-resistant isolates of Staphylococcus aureus
WM Shafer, JJ Iandolo
Infection and Immunity 25 (3), 902-911, 1979
The MtrD protein of Neisseria gonorrhoeae is a member of the resistance/nodulation/division protein family constituting part of an efflux system
KE Hagman, CE Lucas, JT Balthazar, L Snyder, M Nilles, RC Judd, ...
Microbiology 143 (7), 2117-2125, 1997
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