William M. Shafer
William M. Shafer
Professor of Microbiology and Immunology, Emory University School of Medicine
Потвърден имейл адрес: emory.edu
Antimicrobial resistance in Neisseria gonorrhoeae in the 21st century: past, evolution, and future
M Unemo, WM Shafer
Clinical microbiology reviews 27 (3), 587-613, 2014
Degradation of Human Antimicrobial Peptide LL-37 by Staphylococcus aureus-Derived Proteinases
M Sieprawska-Lupa, P Mydel, K Krawczyk, K Wójcik, M Puklo, B Lupa, ...
Antimicrobial agents and chemotherapy 48 (12), 4673-4679, 2004
Modulation of Neisseria gonorrhoeae susceptibility to vertebrate antibacterial peptides due to a member of the resistance/nodulation/division efflux pump family
WM Shafer, XD Qu, AJ Waring, RI Lehrer
Proceedings of the National Academy of Sciences 95 (4), 1829-1833, 1998
Resistance of Neisseria gonorrhoeae to antimicrobial hydrophobic agents is modulated by the mtrRCDE efflux system
KE Hagman, W Pan, BG Spratt, JT Balthazar, RC Judd, WM Shafer
Microbiology 141 (3), 611-622, 1995
Cationic Antimicrobial Peptide Resistance in Neisseria meningitidis
YL Tzeng, KD Ambrose, S Zughaier, X Zhou, YK Miller, WM Shafer, ...
Journal of bacteriology 187 (15), 5387-5396, 2005
Antibiotic resistance in Neisseria gonorrhoeae: origin, evolution, and lessons learned for the future
M Unemo, WM Shafer
Annals of the New York Academy of Sciences 1230 (1), E19-E28, 2011
Cationic antimicrobial proteins isolated from human neutrophil granulocytes in the presence of diisopropyl fluorophosphate.
WM Shafer, LE Martin, JK Spitznagel
Infection and immunity 45 (1), 29, 1984
Transcriptional control of the mtr efflux system of Neisseria gonorrhoeae
KE Hagman, WM Shafer
Journal of bacteriology 177 (14), 4162-4165, 1995
Clinically relevant mutations that cause derepression of the Neisseria gonorrhoeae MtrC‐MtrD‐MtrE Efflux pump system confer different levels of antimicrobial resistance and …
DM Warner, WM Shafer, AE Jerse
Molecular microbiology 70 (2), 462-478, 2008
A gonococcal efflux pump system enhances bacterial survival in a female mouse model of genital tract infection
AE Jerse, ND Sharma, AN Simms, ET Crow, LA Snyder, WM Shafer
Infection and immunity 71 (10), 5576-5582, 2003
Antimicrobial Resistance Expressed by Neisseria gonorrhoeae: A Major Global Public Health Problem in the 21st Century
M Unemo, CD Rio, WM Shafer
Emerging Infections 10, 213-237, 2016
Overexpression of the MtrC-MtrD-MtrE efflux pump due to an mtrR mutation is required for chromosomally mediated penicillin resistance in Neisseria gonorrhoeae
WL Veal, RA Nicholas, WM Shafer
Journal of bacteriology 184 (20), 5619-5624, 2002
The farAB‐encoded efflux pump mediates resistance of gonococci to long‐chained antibacterial fatty acids
EH Lee, WM Shafer
Molecular microbiology 33 (4), 839-845, 1999
CAP37, a human neutrophil-derived chemotactic factor with monocyte specific activity.
HA Pereira, WM Shafer, J Pohl, LE Martin, JK Spitznagel
The Journal of clinical investigation 85 (5), 1468-1476, 1990
Decreased Azithromycin Susceptibility ofNeisseria gonorrhoeae Due to mtrRMutations
L Zarantonelli, G Borthagaray, EH Lee, WM Shafer
Antimicrobial agents and chemotherapy 43 (10), 2468-2472, 1999
The NorM Efflux Pump of Neisseria gonorrhoeae and Neisseria meningitidis Recognizes Antimicrobial Cationic Compounds
C Rouquette-Loughlin, SA Dunham, M Kuhn, JT Balthazar, WM Shafer
Journal of bacteriology 185 (3), 1101-1106, 2003
The MtrD protein of Neisseria gonorrhoeae is a member of the resistance/nodulation/division protein family constituting part of an efflux system
KE Hagman, CE Lucas, JT Balthazar, L Snyder, M Nilles, RC Judd, ...
Microbiology 143 (7), 2117-2125, 1997
Genetics of staphylococcal enterotoxin B in methicillin-resistant isolates of Staphylococcus aureus
WM Shafer, JJ Iandolo
Infection and Immunity 25 (3), 902-911, 1979
Multidrug-resistant gonorrhea: A research and development roadmap to discover new medicines
E Alirol, TE Wi, M Bala, ML Bazzo, XS Chen, C Deal, JAR Dillon, ...
PLoS medicine 14 (7), e1002366, 2017
Regulation of the MtrC-MtrD-MtrE Efflux-Pump System Modulates the In Vivo Fitness of Neisseria gonorrhoeae
DM Warner, JP Folster, WM Shafer, AE Jerse
Journal of Infectious Diseases 196 (12), 1804-1812, 2007
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