Imaging and manipulating proteins in live cells through covalent labeling L Xue, I Karpenko, J Hiblot, K Johnsson Nature Chemical Biology 11 (12), 917-23, 2015 | 202 | 2015 |
Semisynthetic sensor proteins enable metabolic assays at the point of care Q Yu, L Xue, J Hiblot, R Griss, S Fabritz, C Roux, PA Binz, D Haas, ... Science 361 (6407), 1122-1126, 2018 | 125 | 2018 |
Inhaled lactonase reduces Pseudomonas aeruginosa quorum sensing and mortality in rat pneumonia S Hraiech, J Hiblot, J Lafleur, H Lepidi, L Papazian, JM Rolain, D Raoult, ... PLoS One 9 (10), e107125, 2014 | 108 | 2014 |
Characterisation of the organophosphate hydrolase catalytic activity of SsoPox J Hiblot, G Gotthard, E Chabriere, M Elias Scientific reports 2 (1), 779, 2012 | 100 | 2012 |
Differential Active Site Loop Conformations Mediate Promiscuous Activities in the Lactonase SsoPox J Hiblot, G Gotthard, M Elias, E Chabriere PLoS One 8 (9), e75272, 2013 | 96 | 2013 |
Structural and Enzymatic characterization of the lactonase SisLac from Sulfolobus islandicus J Hiblot, G Gotthard, E Chabriere, M Elias Public Library of Science 7 (10), e47028, 2012 | 90 | 2012 |
Kinetic and structural characterization of the self-labeling protein tags HaloTag7, SNAP-tag, and CLIP-tag J Wilhelm, S Kühn, M Tarnawski, G Gotthard, J Tünnermann, ... Biochemistry 60 (33), 2560-2575, 2021 | 87 | 2021 |
Engineered HaloTag variants for fluorescence lifetime multiplexing MS Frei, M Tarnawski, MJ Roberti, B Koch, J Hiblot, K Johnsson Nature methods 19 (1), 65-70, 2022 | 76 | 2022 |
Luciferases with tunable emission wavelengths J Hiblot, Q Yu, MDB Sabbadini, L Reymond, L Xue, A Schena, O Sallin, ... Angewandte Chemie 129 (46), 14748-14752, 2017 | 75 | 2017 |
Chemogenetic control of nanobodies H Farrants, M Tarnawski, TG Müller, S Otsuka, J Hiblot, B Koch, ... Nature methods 17 (3), 279-282, 2020 | 61 | 2020 |
Structural and Enzymatic Characterization of the Phosphotriesterase OPHC2 from Pseudomonas pseudoalcaligenes G Gotthard, J Hiblot, D Gonzalez, M Elias, E Chabriere PLoS One 8 (11), e77995, 2013 | 56 | 2013 |
Crystal structure of VmoLac, a tentative quorum quenching lactonase from the extremophilic crenarchaeon Vulcanisaeta moutnovskia J Hiblot, J Bzdrenga, C Champion, E Chabriere, M Elias Scientific reports 5 (1), 8372, 2015 | 49 | 2015 |
Environmentally Sensitive Color‐Shifting Fluorophores for Bioimaging L Wang, J Hiblot, C Popp, L Xue, K Johnsson Angewandte Chemie International Edition 59 (49), 21880-21884, 2020 | 48 | 2020 |
Rational engineering of a native hyperthermostable lactonase into a broad spectrum phosphotriesterase P Jacquet, J Hiblot, D Daudé, C Bergonzi, G Gotthard, N Armstrong, ... Scientific reports 7 (1), 16745, 2017 | 46 | 2017 |
Exchangeable HaloTag ligands for super-resolution fluorescence microscopy J Kompa, J Bruins, M Glogger, J Wilhelm, MS Frei, M Tarnawski, E D’Este, ... Journal of the American Chemical Society 145 (5), 3075-3083, 2023 | 38 | 2023 |
Sac Pox from the thermoacidophilic crenarchaeon Sulfolobus acidocaldarius is a proficient lactonase J Bzdrenga, J Hiblot, G Gotthard, C Champion, M Elias, E Chabriere BMC research notes 7, 1-9, 2014 | 34 | 2014 |
Fluorescent and bioluminescent calcium indicators with tuneable colors and affinities N Mertes, M Busch, MC Huppertz, CN Hacker, J Wilhelm, CM Gürth, ... Journal of the American Chemical Society 144 (15), 6928-6935, 2022 | 31 | 2022 |
A general method for the development of multicolor biosensors with large dynamic ranges L Hellweg, A Edenhofer, L Barck, MC Huppertz, MS Frei, M Tarnawski, ... Nature Chemical Biology 19 (9), 1147-1157, 2023 | 21 | 2023 |
Ancestral mutations as a tool for solubilizing proteins: The case of a hydrophobic phosphate-binding protein D Gonzalez, J Hiblot, N Darbinian, JC Miller, G Gotthard, S Amini, ... FEBS open bio 4, 121-127, 2014 | 20 | 2014 |
Live-cell fluorescence lifetime multiplexing using synthetic fluorescent probes MS Frei, B Koch, J Hiblot, K Johnsson ACS Chemical Biology 17 (6), 1321-1327, 2022 | 19 | 2022 |