GAPDH controls extracellular vesicle biogenesis and enhances the therapeutic potential of EV mediated siRNA delivery to the brain GH Dar, CC Mendes, WL Kuan, AA Speciale, M Conceição, A Görgens, ... Nature communications 12 (1), 6666, 2021 | 57 | 2021 |
Loss of Krüppel-like factor 3 (KLF3/BKLF) leads to upregulation of the insulin-sensitizing factor adipolin (FAM132A/CTRP12/C1qdc2) KS Bell-Anderson, AP Funnell, H Williams, H Mat Jusoh, T Scully, WF Lim, ... Diabetes 62 (8), 2728-2737, 2013 | 55 | 2013 |
Regions outside the DNA-binding domain are critical for proper in vivo specificity of an archetypal zinc finger transcription factor J Burdach, APW Funnell, KS Mak, CM Artuz, B Wienert, WF Lim, LY Tan, ... Nucleic acids research 42 (1), 276-289, 2014 | 39 | 2014 |
Gene therapy with AR isoform 2 rescues spinal and bulbar muscular atrophy phenotype by modulating AR transcriptional activity WF Lim, M Forouhan, TC Roberts, J Dabney, R Ellerington, AA Speciale, ... Science Advances 7 (34), eabi6896, 2021 | 22 | 2021 |
Directing an artificial zinc finger protein to new targets by fusion to a non-DNA-binding domain WF Lim, J Burdach, APW Funnell, RCM Pearson, KGR Quinlan, ... Nucleic Acids Research 44 (7), 3118-3130, 2016 | 18 | 2016 |
Differential regulation of the α-globin locus by Krüppel-like factor 3 in erythroid and non-erythroid cells APW Funnell, D Vernimmen, WF Lim, KS Mak, B Wienert, GE Martyn, ... BMC molecular biology 15, 1-12, 2014 | 18 | 2014 |
An LNA-amide modification that enhances the cell uptake and activity of phosphorothioate exon-skipping oligonucleotides YR Baker, C Thorpe, J Chen, LM Poller, L Cox, P Kumar, WF Lim, L Lie, ... Nature communications 13 (1), 4036, 2022 | 16 | 2022 |
Variants in ATP6V0A1 cause progressive myoclonus epilepsy and developmental and epileptic encephalopathy LC Bott, M Forouhan, M Lieto, AJ Sala, R Ellerington, JO Johnson, ... Brain communications 3 (4), fcab245, 2021 | 15 | 2021 |
LSD1/PRMT6-targeting gene therapy to attenuate androgen receptor toxic gain-of-function ameliorates spinobulbar muscular atrophy phenotypes in flies and mice R Prakasam, A Bonadiman, R Andreotti, E Zuccaro, D Dalfovo, ... Nature Communications 14 (1), 603, 2023 | 9 | 2023 |
AR cooperates with SMAD4 to maintain skeletal muscle homeostasis M Forouhan, WF Lim, LC Zanetti-Domingues, CJ Tynan, TC Roberts, ... Acta Neuropathologica 143 (6), 713-731, 2022 | 7 | 2022 |
PRMT inhibitor promotes SMN2 exon 7 inclusion and synergizes with nusinersen to rescue SMA mice AJ Kordala, J Stoodley, N Ahlskog, M Hanifi, A Garcia Guerra, A Bhomra, ... EMBO Molecular Medicine 15 (11), e17683, 2023 | 1 | 2023 |
Type I PRMT inhibitor MS023 promotes SMN2 exon 7 inclusion and synergizes with nusinersen to rescue the phenotype of SMA mice AJ Kordala, N Ahlskog, M Hanifi, A Bhomra, J Stoodley, WF Lim, ... bioRxiv, 2022.10. 18.512489, 2022 | 1 | 2022 |
Dystrophin involvement in peripheral circadian SRF signalling CA Betts, A Jagannath, TLE van Westering, M Bowerman, S Banerjee, ... Life Science Alliance 4 (10), 2021 | 1 | 2021 |
Author Correction: GAPDH controls extracellular vesicle biogenesis and enhances the therapeutic potential of EV mediated siRNA delivery to the brain GH Dar, CC Mendes, WL Kuan, AA Speciale, M Conceição, A Görgens, ... Nature Communications 12, 2021 | 1 | 2021 |
Investigating Eukaryotic Elongation Factor 2 Kinase/Eukaryotic Translation Elongation Factor 2 Pathway Regulation and Its Role in Protein Synthesis Impairment during Disuse … N Vilchinskaya, WF Lim, S Belova, TC Roberts, MJA Wood, ... The American Journal of Pathology 193 (6), 813-828, 2023 | | 2023 |
RNA Transcript Diversity in Neuromuscular Research WF Lim, C Rinaldi Journal of Neuromuscular Diseases, 1-10, 2023 | | 2023 |
Investigating eEF2k/eEF2 pathway regulation and its role in protein synthesis impairment during disuse-induced skeletal muscle atrophy. N Vilchinskaya, WF Lim, S Belova, TC Roberts, MJA Wood, ... The American Journal of Pathology, S0002-9440 (23) 00060, 2023 | | 2023 |
Treatment C RINALDI, WF LIM US Patent App. 17/765,116, 2022 | | 2022 |
Oligonucleotide analogues with locked-amide linkages have therapeutic potential Y Baker, C Thorpe, J Chen, L Poller, L Cox, P Kumar, WF Lim, L Lie, ... | | 2022 |
Dystrophin regulates peripheral circadian SRF signalling CA Betts, A Jagannath, TLE van Westering, M Bowerman, S Banerjee, ... bioRxiv, 2021.06. 23.449492, 2021 | | 2021 |