| Structure-guided design of a selective BCL-XL inhibitor G Lessene, PE Czabotar, BE Sleebs, K Zobel, KN Lowes, JM Adams, ... Nature chemical biology 9 (6), 390-397, 2013 | 422 | 2013 |
| Discovery of a Potent and Selective BCL-XL Inhibitor with in Vivo Activity ZF Tao, L Hasvold, L Wang, X Wang, AM Petros, CH Park, ER Boghaert, ... ACS medicinal chemistry letters 5 (10), 1088-1093, 2014 | 307 | 2014 |
| Mitoxantrone, more than just another topoisomerase II poison BJ Evison, BE Sleebs, KG Watson, DR Phillips, SM Cutts Medicinal research reviews 36 (2), 248-299, 2016 | 166 | 2016 |
| Dimeric zanamivir conjugates with various linking groups are potent, long-lasting inhibitors of influenza neuraminidase including H5N1 avian influenza SJF Macdonald, R Cameron, DA Demaine, RJ Fenton, G Foster, D Gower, ... Journal of medicinal chemistry 48 (8), 2964-2971, 2005 | 128 | 2005 |
| Stereoselective syntheses of ephedrine and related 2-aminoalcohols of high optical purity from protected cyanohydrins WR Jackson, HA Jacobs, BR Matthews, GS Jayatilake, KG Watson Tetrahedron letters 31 (10), 1447-1450, 1990 | 122 | 1990 |
| Potent and long-acting dimeric inhibitors of influenza virus neuraminidase are effective at a once-weekly dosing regimen SJF Macdonald, KG Watson, R Cameron, DK Chalmers, DA Demaine, ... Antimicrobial agents and chemotherapy 48 (12), 4542-4549, 2004 | 117 | 2004 |
| Applications of optically active aryl cyanohydrins in the synthesis of α-hydroxy aldehydes, α-hydroxy ketones and β-hydroxy amines WR Jackson, HA Jacobs, GS Jayatilake, BR Matthews, KG Watson Australian Journal of Chemistry 43 (12), 2045-2062, 1990 | 109 | 1990 |
| Trypanothione reductase high-throughput screening campaign identifies novel classes of inhibitors with antiparasitic activity GA Holloway, WN Charman, AH Fairlamb, R Brun, M Kaiser, E Kostewicz, ... Antimicrobial Agents and Chemotherapy 53 (7), 2824-2833, 2009 | 87 | 2009 |
| 2-Ethoxybenzoxazole as a bioisosteric replacement of an ethyl benzoate group in a human rhinovirus (HRV) capsid binder RN Brown, R Cameron, DK Chalmers, S Hamilton, A Luttick, GY Krippner, ... Bioorganic & medicinal chemistry letters 15 (8), 2051-2055, 2005 | 86 | 2005 |
| In vitro activity of expanded-spectrum pyridazinyl oxime ethers related to pirodavir: novel capsid-binding inhibitors with potent antipicornavirus activity DL Barnard, VD Hubbard, DF Smee, RW Sidwell, KGW Watson, ... Antimicrobial agents and chemotherapy 48 (5), 1766-1772, 2004 | 84 | 2004 |
| Discovery of Potent and Selective Benzothiazole Hydrazone Inhibitors of Bcl-XL BE Sleebs, WJA Kersten, S Kulasegaram, G Nikolakopoulos, E Hatzis, ... Journal of Medicinal Chemistry 56 (13), 5514-5540, 2013 | 83 | 2013 |
| Highly potent and long-acting trimeric and tetrameric inhibitors of influenza virus neuraminidase KG Watson, R Cameron, RJ Fenton, D Gower, S Hamilton, B Jin, ... Bioorganic & medicinal chemistry letters 14 (6), 1589-1592, 2004 | 83 | 2004 |
| Synthesis of threo-3-aryl-2, 3-dihydroxypropanoic acid derivatives with high optical purity BR Matthews, H Gountzos, WR Jackson, KG Watson Tetrahedron letters 30 (38), 5157-5158, 1989 | 81 | 1989 |
| A different mechanism for the inhibition of the carboxyltransferase domain of acetyl-coenzyme A carboxylase by tepraloxydim S Xiang, MM Callaghan, KG Watson, L Tong Proceedings of the National Academy of Sciences 106 (49), 20723-20727, 2009 | 71 | 2009 |
| Discovery of 2-iminobenzimidazoles as a new class of trypanothione reductase inhibitor by high-throughput screening GA Holloway, JB Baell, AH Fairlamb, PM Novello, JP Parisot, ... Bioorganic & medicinal chemistry letters 17 (5), 1422-1427, 2007 | 69 | 2007 |
| An orally bioavailable oxime ether capsid binder with potent activity against human rhinovirus KG Watson, RN Brown, R Cameron, DK Chalmers, S Hamilton, B Jin, ... Journal of medicinal chemistry 46 (15), 3181-3184, 2003 | 66 | 2003 |
| Method of detection of influenza virus and compounds for use therein P Reece, WY Wu, B Jin, G Krippner, K Watson US Patent App. 09/823,766, 2002 | 64 | 2002 |
| A concise total synthesis of naamidine A NS Aberle, G Lessene, KG Watson Organic Letters 8 (3), 419-421, 2006 | 61 | 2006 |
| Asymmetric Synthesis of (+)-Diltiazem Hydrochloride KG Watson, YM Fung, G Matthew, GJ Bird, WR Jackson, H Gountzos, ... J. Chem. Soc., Chemical Communications, 1018-1019, 1990 | 54* | 1990 |
| Macromolecular neuraminidase-binding compounds PA Reece, KG Watson, WY Wu, B Jin, GY Krippner US Patent 6,680,054, 2004 | 50 | 2004 |
Brad SleebsWalter and Eliza Hall InstituteVerified email at wehi.edu.au
