| Host genotype-specific therapies can optimize the inflammatory response to mycobacterial infections DM Tobin, FJ Roca, SF Oh, R McFarland, TW Vickery, JP Ray, DC Ko, ... Cell 148 (3), 434-446, 2012 | 638 | 2012 |
| Cell-autonomous death of cerebellar purkinje neurons with autophagy in Niemann-Pick type C disease DC Ko, L Milenkovic, SM Beier, H Manuel, JA Buchanan, MP Scott PLoS genetics 1 (1), e7, 2005 | 273 | 2005 |
| Dynamic movements of organelles containing Niemann-Pick C1 protein: NPC1 involvement in late endocytic events DC Ko, MD Gordon, JY Jin, MP Scott Molecular biology of the cell 12 (3), 601-614, 2001 | 273 | 2001 |
| The integrity of a cholesterol-binding pocket in Niemann–Pick C2 protein is necessary to control lysosome cholesterol levels DC Ko, J Binkley, A Sidow, MP Scott Proceedings of the National Academy of Sciences 100 (5), 2518-2525, 2003 | 250 | 2003 |
| Binding between the Niemann–Pick C1 protein and a photoactivatable cholesterol analog requires a functional sterol-sensing domain N Ohgami, DC Ko, M Thomas, MP Scott, CCY Chang, TY Chang Proceedings of the National Academy of Sciences 101 (34), 12473-12478, 2004 | 249 | 2004 |
| Antitermination by bacteriophage λ Q protein JW Roberts, W Yarnell, E Bartlett, J Guo, M Marr, DC Ko, H Sun, ... Cold Spring Harbor symposia on quantitative biology 63, 319-326, 1998 | 186 | 1998 |
| Analysis of a Food-Borne Fungal Pathogen Outbreak: Virulence and Genome of a Mucor circinelloides Isolate from Yogurt SC Lee, RB Billmyre, A Li, S Carson, SM Sykes, EY Huh, P Mieczkowski, ... MBio 5 (4), 10.1128/mbio. 01390-14, 2014 | 126 | 2014 |
| Human epistatic interaction controls IL7R splicing and increases multiple sclerosis risk G Galarza-Muñoz, FBS Briggs, I Evsyukova, G Schott-Lerner, ... Cell 169 (1), 72-84. e13, 2017 | 107 | 2017 |
| A genome-wide in vitro bacterial-infection screen reveals human variation in the host response associated with inflammatory disease DC Ko, KP Shukla, C Fong, M Wasnick, MJ Brittnacher, MM Wurfel, ... The American Journal of Human Genetics 85 (2), 214-227, 2009 | 94 | 2009 |
| Calcineurin orchestrates dimorphic transitions, antifungal drug responses and host–pathogen interactions of the pathogenic mucoralean fungus Mucor circinelloides SC Lee, A Li, S Calo, M Inoue, NK Tonthat, JM Bain, J Louw, ... Molecular microbiology 97 (5), 844-865, 2015 | 91 | 2015 |
| A surface of Escherichia coli sigma 70 required for promoter function and antitermination by phage lambda Q protein. K DC, M MT, G J, R JW. Genes & Development 12 (20), 3276-85, 1998 | 76 | 1998 |
| Functional genetic screen of human diversity reveals that a methionine salvage enzyme regulates inflammatory cell death DC Ko, ER Gamazon, KP Shukla, RA Pfuetzner, D Whittington, TD Holden, ... Proceedings of the National Academy of Sciences 109 (35), E2343-E2352, 2012 | 72 | 2012 |
| Salmonella activation of STAT3 signaling by SarA effector promotes intracellular replication and production of IL-10 SL Jaslow, KD Gibbs, WF Fricke, L Wang, KJ Pittman, MK Mammel, ... Cell reports 23 (12), 3525-3536, 2018 | 70 | 2018 |
| The Salmonella secreted effector SarA/SteE mimics cytokine receptor signaling to activate STAT3 KD Gibbs, EJ Washington, SL Jaslow, JS Bourgeois, MW Foster, R Guo, ... Cell host & microbe 27 (1), 129-139. e4, 2020 | 62 | 2020 |
| An Enzyme That Inactivates the Inflammatory Mediator Leukotriene B4 Restricts Mycobacterial Infection DM Tobin, FJ Roca, JP Ray, DC Ko, L Ramakrishnan PloS one 8 (7), e67828, 2013 | 62 | 2013 |
| Human genetic and metabolite variation reveals that methylthioadenosine is a prognostic biomarker and an inflammatory regulator in sepsis L Wang, ER Ko, JJ Gilchrist, KJ Pittman, A Rautanen, M Pirinen, ... Science Advances 3 (3), e1602096, 2017 | 55 | 2017 |
| Human genetic variation in VAC14 regulates Salmonella invasion and typhoid fever through modulation of cholesterol MI Alvarez, LC Glover, P Luo, L Wang, E Theusch, SH Oehlers, ... Proceedings of the National Academy of Sciences 114 (37), E7746-E7755, 2017 | 54 | 2017 |
| An atlas of genetic variation linking pathogen-induced cellular traits to human disease L Wang, KJ Pittman, JR Barker, RE Salinas, IB Stanaway, GD Williams, ... Cell host & microbe 24 (2), 308-323. e6, 2018 | 53 | 2018 |
| An atlas connecting shared genetic architecture of human diseases and molecular phenotypes provides insight into COVID-19 susceptibility L Wang, TJ Balmat, AL Antonia, FJ Constantine, R Henao, TW Burke, ... Genome medicine 13 (1), 83, 2021 | 51 | 2021 |
| Multiple surface regions on the Niemann-Pick C2 protein facilitate intracellular cholesterol transport LA McCauliff, Z Xu, R Li, S Kodukula, DC Ko, MP Scott, PC Kahn, J Storch Journal of Biological Chemistry 290 (45), 27321-27331, 2015 | 50 | 2015 |
Liuyang WangDuke UniversityПотвърден имейл адрес: duke.edu
