| Macromolecular modeling and design in Rosetta: recent methods and frameworks JK Leman, BD Weitzner, SM Lewis, J Adolf-Bryfogle, N Alam, RF Alford, ... Nature methods 17 (7), 665-680, 2020 | 650 | 2020 |
| High frequency of shared clonotypes in human B cell receptor repertoires C Soto, RG Bombardi, A Branchizio, N Kose, P Matta, AM Sevy, ... Nature 566 (7744), 398-402, 2019 | 294 | 2019 |
| Protocols for molecular modeling with Rosetta3 and RosettaScripts BJ Bender, A Cisneros III, AM Duran, JA Finn, D Fu, AD Lokits, BK Mueller, ... Biochemistry 55 (34), 4748-4763, 2016 | 203 | 2016 |
| Multifunctional pan-ebolavirus antibody recognizes a site of broad vulnerability on the ebolavirus glycoprotein P Gilchuk, N Kuzmina, PA Ilinykh, K Huang, BM Gunn, A Bryan, ... Immunity 49 (2), 363-374. e10, 2018 | 79 | 2018 |
| Structural basis for nonneutralizing antibody competition at antigenic site II of the respiratory syncytial virus fusion protein JJ Mousa, MF Sauer, AM Sevy, JA Finn, JT Bates, G Alvarado, HG King, ... Proceedings of the National Academy of Sciences 113 (44), E6849-E6858, 2016 | 48 | 2016 |
| Design of protein multi-specificity using an independent sequence search reduces the barrier to low energy sequences AM Sevy, TM Jacobs, JE Crowe Jr, J Meiler PLoS computational biology 11 (7), e1004300, 2015 | 48 | 2015 |
| Epitope mapping of inhibitory antibodies targeting the C2 domain of coagulation factor VIII by hydrogen–deuterium exchange mass spectrometry AM Sevy, JF Healey, W Deng, PC Spiegel, SL Meeks, R Li Journal of Thrombosis and Haemostasis 11 (12), 2128-2136, 2013 | 48 | 2013 |
| Modeling immunity with Rosetta: methods for antibody and antigen design CT Schoeder, S Schmitz, J Adolf-Bryfogle, AM Sevy, JA Finn, MF Sauer, ... Biochemistry 60 (11), 825-846, 2021 | 39 | 2021 |
| Multistate design of influenza antibodies improves affinity and breadth against seasonal viruses AM Sevy, NC Wu, IM Gilchuk, EH Parrish, S Burger, D Yousif, MBM Nagel, ... Proceedings of the National Academy of Sciences 116 (5), 1597-1602, 2019 | 27 | 2019 |
| Antibodies: Computer‐aided prediction of structure and design of function AM Sevy, J Meiler Antibodies for Infectious Diseases, 173-190, 2015 | 25 | 2015 |
| Computationally designed cyclic peptides derived from an antibody loop increase breadth of binding for influenza variants AM Sevy, IM Gilchuk, BP Brown, NG Bozhanova, R Nargi, M Jensen, ... Structure 28 (10), 1114-1123. e4, 2020 | 24 | 2020 |
| Multi-state design of flexible proteins predicts sequences optimal for conformational change MF Sauer, AM Sevy, JE Crowe Jr, J Meiler PLOS Computational Biology 16 (2), e1007339, 2020 | 23 | 2020 |
| Discovery of Marburg virus neutralizing antibodies from virus-naïve human antibody repertoires using large-scale structural predictions NG Bozhanova, AK Sangha, AM Sevy, P Gilchuk, K Huang, RS Nargi, ... Proceedings of the National Academy of Sciences 117 (49), 31142-31148, 2020 | 17 | 2020 |
| Structure-and sequence-based design of synthetic single-domain antibody libraries AM Sevy, MT Chen, M Castor, T Sylvia, H Krishnamurthy, A Ishchenko, ... Protein Engineering, Design and Selection 33, gzaa028, 2020 | 15 | 2020 |
| Integrating linear optimization with structural modeling to increase HIV neutralization breadth AM Sevy, S Panda, JE Crowe Jr, J Meiler, Y Vorobeychik PLoS computational biology 14 (2), e1005999, 2018 | 15 | 2018 |
| Identification of structurally related antibodies in antibody sequence databases using rosetta-derived position-specific scoring JA Finn, J Dong, AM Sevy, E Parrish, I Gilchuk, R Nargi, M Scarlett-Jones, ... Structure 28 (10), 1124-1130. e5, 2020 | 10 | 2020 |
| Immune repertoire fingerprinting by principal component analysis reveals shared features in subject groups with common exposures AM Sevy, C Soto, RG Bombardi, J Meiler, JE Crowe BMC bioinformatics 20, 1-10, 2019 | 8 | 2019 |
| Cooperative Binding Of Anti-Factor VIII Inhibitors and Induced Conformational Change Detected By Hydrogen-Deuterium Exchange Mass Spectrometry SL Meeks, AM Sevy, JF Healey, W Deng, PC Spiegel, R Li Blood 122 (21), 1088, 2013 | 2 | 2013 |
| ErrorX: automated error correction for immune repertoire sequencing datasets AM Sevy bioRxiv, 2020.02. 17.952408, 2020 | 1 | 2020 |
| Binding proteins and antigen binding fragments thereof that bind abeta AM Sevy, MT Chen US Patent App. 18/245,563, 2023 | | 2023 |
