| FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation JJ Hu, X Liu, S Xia, Z Zhang, Y Zhang, J Zhao, J Ruan, X Luo, X Lou, ... Nature immunology 21 (7), 736-745, 2020 | 631 | 2020 |
| DPP9 sequesters the C terminus of NLRP1 to repress inflammasome activation LR Hollingsworth, H Sharif, AR Griswold, P Fontana, J Mintseris, ... Nature 592 (7856), 778-783, 2021 | 129 | 2021 |
| Mechanism and regulation of gasdermin-mediated cell death S Xia, LR Hollingsworth, H Wu Cold Spring Harbor Perspectives in Biology 12 (3), a036400, 2020 | 116 | 2020 |
| Bromodomain inhibitors correct bioenergetic deficiency caused by mitochondrial disease complex I mutations JJ Barrow, E Balsa, F Verdeguer, CDJ Tavares, MS Soustek, ... Molecular cell 64 (1), 163-175, 2016 | 57 | 2016 |
| Mechanism of filament formation in UPA-promoted CARD8 and NLRP1 inflammasomes LR Hollingsworth, L David, Y Li, AR Griswold, J Ruan, H Sharif, P Fontana, ... Nature Communications 12 (1), 1-13, 2021 | 55* | 2021 |
| Dipeptidyl peptidase 9 sets a threshold for CARD8 inflammasome formation by sequestering its active C-terminal fragment H Sharif, LR Hollingsworth, AR Griswold, JC Hsiao, Q Wang, ... Immunity 54 (7), 1392-1404. e10, 2021 | 50 | 2021 |
| HIV-1 Env gp41 transmembrane domain dynamics are modulated by lipid, water, and ion interactions LR Hollingsworth, JA Lemkul, DR Bevan, AM Brown Biophysical journal 115 (1), 84-94, 2018 | 15 | 2018 |
| Computational study of HIV gp120 as a target for polyanionic entry inhibitors: Exploiting the V3 loop region LR Hollingsworth IV, AM Brown, RD Gandour, DR Bevan PLoS One 13 (1), e0190658, 2018 | 9 | 2018 |
| NINJ1 mediates plasma membrane rupture by cutting and releasing membrane disks L David, JP Borges, LR Hollingsworth, A Volchuk, I Jansen, E Garlick, ... Cell, 2024 | 4* | 2024 |
| Molecular evolution of genes encoding allergen proteins in the peanuts genus Arachis: Structural and functional implications KW Hilu, SA Friend, V Vallanadu, AM Brown, LR Hollingsworth IV, ... Plos one 14 (11), e0222440, 2019 | 3 | 2019 |
| Spatiotemporal proteomic profiling of cellular responses to NLRP3 agonists LR Hollingsworth, P Veeraraghavan, J Paulo, JW Harper https://harperlab.pubpub.org/pub/nlrp3/, 2024 | | 2024 |
| Host E3 ubiquitin ligase ITCH mediates Toxoplasma gondii effector GRA35-triggered NLRP1 inflammasome activation and cell-autonomous immunity Y Wang, LR Hollingsworth, LO Sangaré, TC Paredes-Santos, ... Mbio, e03302-23, 2024 | | 2024 |
| Molecular mechanisms for the regulation and assembly of the NLRP1 and CARD8 inflammasomes LR Hollingsworth Harvard University, 2022 | | 2022 |
| Speak out against tuition waiver taxes LR Hollingsworth IV, P Veeraraghavan, KJ Wu, DE McCoy, A Van Dervort, ... Science 358 (6369), 1395-1395, 2017 | | 2017 |
| Utilizing Computational Techniques to Accelerate Discovery in Peanut Allergenicity: A Case Study LR Hollingsworth IV, AM Brown, DR Bevan Proceedings of the Practice and Experience in Advanced Research Computing …, 2017 | | 2017 |
