Следене
Jonathan Weinstein
Jonathan Weinstein
Department of Biomolecular Science, Weizmann Institute of Science, Israel
Потвърден имейл адрес: weizmann.ac.il
Заглавие
Позовавания
Позовавания
Година
Mega-scale experimental analysis of protein folding stability in biology and design
K Tsuboyama, J Dauparas, J Chen, E Laine, Y Mohseni Behbahani, ...
Nature 620 (7973), 434-444, 2023
1532023
Mutational scanning reveals the determinants of protein insertion and association energetics in the plasma membrane
A Elazar, J Weinstein, I Biran, Y Fridman, E Bibi, SJ Fleishman
Elife 5, e12125, 2016
822016
Stable and functionally diverse versatile peroxidases designed directly from sequences
S Barber-Zucker, V Mindel, E Garcia-Ruiz, JJ Weinstein, M Alcalde, ...
Journal of the American Chemical Society 144 (8), 3564-3571, 2022
552022
PROSS 2: a new server for the design of stable and highly expressed protein variants
JJ Weinstein, A Goldenzweig, SY Hoch, SJ Fleishman
Bioinformatics 37 (1), 123-125, 2021
552021
Interplay between hydrophobicity and the positive-inside rule in determining membrane-protein topology
A Elazar, JJ Weinstein, J Prilusky, SJ Fleishman
Proceedings of the National Academy of Sciences 113 (37), 10340-10345, 2016
552016
Structure and receptor recognition by the Lassa virus spike complex
M Katz, J Weinstein, M Eilon-Ashkenazy, K Gehring, H Cohen-Dvashi, ...
Nature 603 (7899), 174-179, 2022
442022
De novo-designed transmembrane domains tune engineered receptor functions
A Elazar, NJ Chandler, AS Davey, JY Weinstein, JV Nguyen, R Trenker, ...
Elife 11, e75660, 2022
412022
Practically useful protein-design methods combining phylogenetic and atomistic calculations
J Weinstein, O Khersonsky, SJ Fleishman
Current opinion in structural biology 63, 58-64, 2020
372020
A lipophilicity-based energy function for membrane-protein modelling and design
SJF Jonathan Yaacov Weinstein, Assaf Elazar
PLOS Computational Biology, 2019
372019
Designed active-site library reveals thousands of functional GFP variants
JY Weinstein, C Martí-Gómez, R Lipsh-Sokolik, SY Hoch, D Liebermann, ...
Nature communications 14 (1), 2890, 2023
242023
Combined crystal structure of a type I cohesin: Mutation and affinity binding studies reveal structural determinants of cohesin-dockerin specificities
K Cameron, JY Weinstein, O Zhivin, P Bule, SJ Fleishman, VD Alves, ...
Journal of Biological Chemistry 290 (26), 16215-16225, 2015
182015
Computational design and molecular dynamics simulations suggest the mode of substrate binding in ceramide synthases
ID Zelnik, B Mestre, JJ Weinstein, T Dingjan, S Izrailov, S Ben-Dor, ...
Nature communications 14 (1), 2330, 2023
162023
Coronacept–a potent immunoadhesin against SARS-CoV-2
H Cohen-Dvashi, J Weinstein, M Katz, M Eilon, Y Mor, A Shimon, ...
bioRxiv, 2020.08. 12.247940, 2020
142020
Stabilization of the SARS-CoV-2 receptor binding domain by protein core redesign and deep mutational scanning
AC Leonard, JJ Weinstein, PJ Steiner, AH Erbse, SJ Fleishman, ...
Protein engineering, design and selection 35, gzac002, 2022
122022
Insights into a type III cohesin–dockerin recognition interface from the cellulose‐degrading bacterium Ruminococcus flavefaciens
JY Weinstein, M Slutzki, A Karpol, Y Barak, O Gul, R Lamed, EA Bayer, ...
Journal of Molecular Recognition 28 (3), 148-154, 2015
92015
Anti-SARS-CoV-2 immunoadhesin remains effective against Omicron and other emerging variants of concern
H Cohen-Dvashi, J Weinstein, M Katz, M Eilon-Ashkenazy, Y Mor, ...
Iscience 25 (10), 2022
62022
De novo designed receptor transmembrane domains enhance CAR-T cell cytotoxicity and attenuate cytokine release
A Elazar, NJ Chandler, AS Davey, JY Weinstein, JV Nguyen, R Trenker, ...
bioRxiv, 2020.07. 26.221598, 2020
52020
Computational design of BclxL inhibitors that target transmembrane domain interactions
G Duart, A Elazar, JY Weinstein, L Gadea-Salom, J Ortiz-Mateu, ...
Proceedings of the National Academy of Sciences 120 (11), e2219648120, 2023
42023
One‐shot design elevates functional expression levels of a voltage‐gated potassium channel
JJ Weinstein, C Saikia, I Karbat, A Goldenzweig, E Reuveny, ...
Protein Science 33 (6), e4995, 2024
22024
DESIGNER CAR TRANSMEMBRANE DOMAINS PROVIDE PREDICTABLY TUNABLE T CELL FUNCTIONAL POTENCY
M Call, A Elazar, N Chandler, A Davey, J Weinstein, R Trenker, J Nguyen, ...
HUMAN GENE THERAPY 34 (21-22), A29-A29, 2023
2023
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