Mega-scale experimental analysis of protein folding stability in biology and design K Tsuboyama, J Dauparas, J Chen, E Laine, Y Mohseni Behbahani, ... Nature 620 (7973), 434-444, 2023 | 153 | 2023 |
Mutational scanning reveals the determinants of protein insertion and association energetics in the plasma membrane A Elazar, J Weinstein, I Biran, Y Fridman, E Bibi, SJ Fleishman Elife 5, e12125, 2016 | 82 | 2016 |
Stable and functionally diverse versatile peroxidases designed directly from sequences S Barber-Zucker, V Mindel, E Garcia-Ruiz, JJ Weinstein, M Alcalde, ... Journal of the American Chemical Society 144 (8), 3564-3571, 2022 | 55 | 2022 |
PROSS 2: a new server for the design of stable and highly expressed protein variants JJ Weinstein, A Goldenzweig, SY Hoch, SJ Fleishman Bioinformatics 37 (1), 123-125, 2021 | 55 | 2021 |
Interplay between hydrophobicity and the positive-inside rule in determining membrane-protein topology A Elazar, JJ Weinstein, J Prilusky, SJ Fleishman Proceedings of the National Academy of Sciences 113 (37), 10340-10345, 2016 | 55 | 2016 |
Structure and receptor recognition by the Lassa virus spike complex M Katz, J Weinstein, M Eilon-Ashkenazy, K Gehring, H Cohen-Dvashi, ... Nature 603 (7899), 174-179, 2022 | 44 | 2022 |
De novo-designed transmembrane domains tune engineered receptor functions A Elazar, NJ Chandler, AS Davey, JY Weinstein, JV Nguyen, R Trenker, ... Elife 11, e75660, 2022 | 41 | 2022 |
Practically useful protein-design methods combining phylogenetic and atomistic calculations J Weinstein, O Khersonsky, SJ Fleishman Current opinion in structural biology 63, 58-64, 2020 | 37 | 2020 |
A lipophilicity-based energy function for membrane-protein modelling and design SJF Jonathan Yaacov Weinstein, Assaf Elazar PLOS Computational Biology, 2019 | 37 | 2019 |
Designed active-site library reveals thousands of functional GFP variants JY Weinstein, C Martí-Gómez, R Lipsh-Sokolik, SY Hoch, D Liebermann, ... Nature communications 14 (1), 2890, 2023 | 24 | 2023 |
Combined crystal structure of a type I cohesin: Mutation and affinity binding studies reveal structural determinants of cohesin-dockerin specificities K Cameron, JY Weinstein, O Zhivin, P Bule, SJ Fleishman, VD Alves, ... Journal of Biological Chemistry 290 (26), 16215-16225, 2015 | 18 | 2015 |
Computational design and molecular dynamics simulations suggest the mode of substrate binding in ceramide synthases ID Zelnik, B Mestre, JJ Weinstein, T Dingjan, S Izrailov, S Ben-Dor, ... Nature communications 14 (1), 2330, 2023 | 16 | 2023 |
Coronacept–a potent immunoadhesin against SARS-CoV-2 H Cohen-Dvashi, J Weinstein, M Katz, M Eilon, Y Mor, A Shimon, ... bioRxiv, 2020.08. 12.247940, 2020 | 14 | 2020 |
Stabilization of the SARS-CoV-2 receptor binding domain by protein core redesign and deep mutational scanning AC Leonard, JJ Weinstein, PJ Steiner, AH Erbse, SJ Fleishman, ... Protein engineering, design and selection 35, gzac002, 2022 | 12 | 2022 |
Insights into a type III cohesin–dockerin recognition interface from the cellulose‐degrading bacterium Ruminococcus flavefaciens JY Weinstein, M Slutzki, A Karpol, Y Barak, O Gul, R Lamed, EA Bayer, ... Journal of Molecular Recognition 28 (3), 148-154, 2015 | 9 | 2015 |
Anti-SARS-CoV-2 immunoadhesin remains effective against Omicron and other emerging variants of concern H Cohen-Dvashi, J Weinstein, M Katz, M Eilon-Ashkenazy, Y Mor, ... Iscience 25 (10), 2022 | 6 | 2022 |
De novo designed receptor transmembrane domains enhance CAR-T cell cytotoxicity and attenuate cytokine release A Elazar, NJ Chandler, AS Davey, JY Weinstein, JV Nguyen, R Trenker, ... bioRxiv, 2020.07. 26.221598, 2020 | 5 | 2020 |
Computational design of BclxL inhibitors that target transmembrane domain interactions G Duart, A Elazar, JY Weinstein, L Gadea-Salom, J Ortiz-Mateu, ... Proceedings of the National Academy of Sciences 120 (11), e2219648120, 2023 | 4 | 2023 |
One‐shot design elevates functional expression levels of a voltage‐gated potassium channel JJ Weinstein, C Saikia, I Karbat, A Goldenzweig, E Reuveny, ... Protein Science 33 (6), e4995, 2024 | 2 | 2024 |
DESIGNER CAR TRANSMEMBRANE DOMAINS PROVIDE PREDICTABLY TUNABLE T CELL FUNCTIONAL POTENCY M Call, A Elazar, N Chandler, A Davey, J Weinstein, R Trenker, J Nguyen, ... HUMAN GENE THERAPY 34 (21-22), A29-A29, 2023 | | 2023 |