| CMTM6 maintains the expression of PD-L1 and regulates anti-tumour immunity ML Burr, CE Sparbier, YC Chan, JC Williamson, K Woods, PA Beavis, ... Nature 549 (7670), 101-105, 2017 | 738 | 2017 |
| BET inhibitor resistance emerges from leukaemia stem cells CY Fong, O Gilan, EYN Lam, AF Rubin, S Ftouni, D Tyler, K Stanley, ... Nature 525 (7570), 538-542, 2015 | 509 | 2015 |
| An evolutionarily conserved function of polycomb silences the MHC class I antigen presentation pathway and enables immune evasion in cancer ML Burr, CE Sparbier, KL Chan, YC Chan, A Kersbergen, EYN Lam, ... Cancer cell 36 (4), 385-401. e8, 2019 | 418 | 2019 |
| Selective targeting of BD1 and BD2 of the BET proteins in cancer and immunoinflammation O Gilan, I Rioja, K Knezevic, MJ Bell, MM Yeung, NR Harker, EYN Lam, ... Science 368 (6489), 387-394, 2020 | 297 | 2020 |
| Multiplexed proteome dynamics profiling reveals mechanisms controlling protein homeostasis MM Savitski, N Zinn, M Faelth-Savitski, D Poeckel, S Gade, I Becher, ... Cell 173 (1), 260-274. e25, 2018 | 200 | 2018 |
| Dynamic molecular monitoring reveals that SWI–SNF mutations mediate resistance to ibrutinib plus venetoclax in mantle cell lymphoma R Agarwal, YC Chan, CS Tam, T Hunter, D Vassiliadis, CE Teh, ... Nature medicine 25 (1), 119-129, 2019 | 166 | 2019 |
| CDK9 inhibition by dinaciclib potently suppresses Mcl-1 to induce durable apoptotic responses in aggressive MYC-driven B-cell lymphoma in vivo GP Gregory, SJ Hogg, LM Kats, E Vidacs, AJ Baker, O Gilan, M Lefebure, ... Leukemia 29 (6), 1437-1441, 2015 | 147 | 2015 |
| Targeting enhancer switching overcomes non-genetic drug resistance in acute myeloid leukaemia CC Bell, KA Fennell, YC Chan, F Rambow, MM Yeung, D Vassiliadis, ... Nature communications 10 (1), 2723, 2019 | 146 | 2019 |
| Click chemistry enables preclinical evaluation of targeted epigenetic therapies DS Tyler, J Vappiani, T Cañeque, EYN Lam, A Ward, O Gilan, YC Chan, ... Science 356 (6345), 1397-1401, 2017 | 131 | 2017 |
| Principles and mechanisms of non-genetic resistance in cancer CC Bell, O Gilan British journal of cancer 122 (4), 465-472, 2020 | 128 | 2020 |
| Functional interdependence of BRD4 and DOT1L in MLL leukemia O Gilan, EYN Lam, I Becher, D Lugo, E Cannizzaro, G Joberty, A Ward, ... Nature structural & molecular biology 23 (7), 673-681, 2016 | 103 | 2016 |
| Widespread FRA1-dependent control of mesenchymal transdifferentiation programs in colorectal cancer cells J Diesch, E Sanij, O Gilan, C Love, H Tran, NI Fleming, J Ellul, M Amalia, ... PloS one 9 (3), e88950, 2014 | 85 | 2014 |
| CDK4/6 inhibition reprograms the breast cancer enhancer landscape by stimulating AP-1 transcriptional activity AC Watt, P Cejas, MJ DeCristo, O Metzger-Filho, EYN Lam, X Qiu, ... Nature Cancer 2 (1), 34-48, 2021 | 58 | 2021 |
| Jarid2 regulates hematopoietic stem cell function by acting with polycomb repressive complex 2 SA Kinkel, R Galeev, C Flensburg, A Keniry, K Breslin, O Gilan, S Lee, ... Blood, The Journal of the American Society of Hematology 125 (12), 1890-1900, 2015 | 52 | 2015 |
| A 19S proteasomal subunit cooperates with an ERK MAPK-regulated degron to regulate accumulation of Fra-1 in tumour cells JL Pakay, J Diesch, O Gilan, YY Yip, E Sayan, W Kolch, JM Mariadason, ... Oncogene 31 (14), 1817-1824, 2012 | 34 | 2012 |
| Regulation of perforin activation and pre‐synaptic toxicity through C‐terminal glycosylation IG House, CM House, AJ Brennan, O Gilan, MA Dawson, JC Whisstock, ... EMBO reports 18 (10), 1775-1785, 2017 | 33 | 2017 |
| An Erg-driven transcriptional program controls B cell lymphopoiesis AP Ng, HD Coughlan, S Hediyeh-Zadeh, K Behrens, TM Johanson, ... Nature Communications 11 (1), 3013, 2020 | 32 | 2020 |
| Id2 and E proteins orchestrate the initiation and maintenance of MLL-rearranged acute myeloid leukemia M Ghisi, L Kats, F Masson, J Li, T Kratina, E Vidacs, O Gilan, MA Doyle, ... Cancer Cell 30 (1), 59-74, 2016 | 31 | 2016 |
| PR55α-containing protein phosphatase 2A complexes promote cancer cell migration and invasion through regulation of AP-1 transcriptional activity O Gilan, J Diesch, M Amalia, K Jastrzebski, AC Chueh, NM Verrills, ... Oncogene 34 (10), 1333-1339, 2015 | 27 | 2015 |
| Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes CE Sparbier, A Gillespie, J Gomez, N Kumari, A Motazedian, KL Chan, ... Nature cell biology 25 (2), 258-272, 2023 | 11 | 2023 |
