Calcific aortic valve disease: not simply a degenerative process a review and agenda for research from the National Heart and Lung and Blood Institute Aortic Stenosis Working Group NM Rajamannan, FJ Evans, E Aikawa, KJ Grande-Allen, LL Demer, ... Circulation 124 (16), 1783, 2011 | 1014 | 2011 |
Dual growth factor delivery and controlled scaffold degradation enhance in vivo bone formation by transplanted bone marrow stromal cells CA Simmons, E Alsberg, S Hsiong, WJ Kim, DJ Mooney Bone 35 (2), 562-569, 2004 | 551 | 2004 |
Boning up on Wolff's Law: mechanical regulation of the cells that make and maintain bone JH Chen, C Liu, L You, CA Simmons Journal of biomechanics 43 (1), 108-118, 2010 | 509 | 2010 |
Introductory biomechanics: from cells to organisms CR Ethier, CA Simmons Cambridge University Press, 2007 | 503 | 2007 |
Calcification by valve interstitial cells is regulated by the stiffness of the extracellular matrix CYY Yip, JH Chen, R Zhao, CA Simmons Arteriosclerosis, thrombosis, and vascular biology 29 (6), 936-942, 2009 | 447 | 2009 |
Cyclic strain enhances matrix mineralization by adult human mesenchymal stem cells via the extracellular signal-regulated kinase (ERK1/2) signaling pathway CA Simmons, S Matlis, AJ Thornton, S Chen, CY Wang, DJ Mooney Journal of biomechanics 36 (8), 1087-1096, 2003 | 430 | 2003 |
Influence of substrate stiffness on the phenotype of heart cells B Bhana, RK Iyer, WLK Chen, R Zhao, KL Sider, M Likhitpanichkul, ... Biotechnology and bioengineering 105 (6), 1148-1160, 2010 | 429 | 2010 |
Spatial heterogeneity of endothelial phenotypes correlates with side-specific vulnerability to calcification in normal porcine aortic valves CA Simmons, GR Grant, E Manduchi, PF Davies Circulation research 96 (7), 792-799, 2005 | 376 | 2005 |
Cell–matrix interactions in the pathobiology of calcific aortic valve disease: critical roles for matricellular, matricrine, and matrix mechanics cues JH Chen, CA Simmons Circulation research 108 (12), 1510-1524, 2011 | 375 | 2011 |
Does confirmatory tumor biopsy alter the management of breast cancer patients with distant metastases? C Simmons, N Miller, W Geddie, D Gianfelice, M Oldfield, G Dranitsaris, ... Annals of oncology 20 (9), 1499-1504, 2009 | 372 | 2009 |
Mesenchymal stromal/stem cells in regenerative medicine and tissue engineering REB Fitzsimmons, MS Mazurek, A Soos, CA Simmons Stem cells international 2018 (1), 8031718, 2018 | 365 | 2018 |
Design and formulation of functional pluripotent stem cell-derived cardiac microtissues N Thavandiran, N Dubois, A Mikryukov, S Massé, B Beca, CA Simmons, ... Proceedings of the National Academy of Sciences 110 (49), E4698-E4707, 2013 | 317 | 2013 |
Bone Regeneration via a Mineral Substrate and Induced Angiogenesis WL Murphy, CA Simmons, D Kaigler, DJ Mooney Journal of dental research 83 (3), 204-210, 2004 | 294 | 2004 |
Identification and characterization of aortic valve mesenchymal progenitor cells with robust osteogenic calcification potential JH Chen, CYY Yip, ED Sone, CA Simmons The American journal of pathology 174 (3), 1109-1119, 2009 | 276 | 2009 |
Macro-and microscale fluid flow systems for endothelial cell biology EWK Young, CA Simmons Lab on a Chip 10 (2), 143-160, 2010 | 262 | 2010 |
Bone regeneration in a rat cranial defect with delivery of PEI-condensed plasmid DNA encoding for bone morphogenetic protein-4 (BMP-4) YC Huang, C Simmons, D Kaigler, KG Rice, DJ Mooney Gene therapy 12 (5), 418-426, 2005 | 253 | 2005 |
β-catenin mediates mechanically regulated, transforming growth factor-β1–induced myofibroblast differentiation of aortic valve interstitial cells JH Chen, WLK Chen, KL Sider, CYY Yip, CA Simmons Arteriosclerosis, thrombosis, and vascular biology 31 (3), 590-597, 2011 | 236 | 2011 |
Osseointegration of sintered porous‐surfaced and plasma spray–coated implants: An animal model study of early postimplantation healing response and mechanical stability CA Simmons, N Valiquette, RM Pilliar Journal of Biomedical Materials Research 47 (2), 127-138, 1999 | 232 | 1999 |
Mechanobiology of the aortic heart valve JT Butcher, CA Simmons, JN Warnock Journal of Heart Valve Disease 17 (1), 62, 2008 | 231 | 2008 |
In Situ Mechanical Characterization of the Cell Nucleus by Atomic Force Microscopy H Liu, J Wen, Y Xiao, J Liu, S Hopyan, M Radisic, CA Simmons, Y Sun ACS nano 8 (4), 3821-3828, 2014 | 224 | 2014 |