Cofactor binding evokes latent differences in DNA binding specificity between Hox proteins M Slattery, T Riley, P Liu, N Abe, P Gomez-Alcala, I Dror, T Zhou, R Rohs, ... Cell 147 (6), 1270-1282, 2011 | 561 | 2011 |
Genomic regions flanking E-box binding sites influence DNA binding specificity of bHLH transcription factors through DNA shape R Gordân, N Shen, I Dror, T Zhou, J Horton, R Rohs, ML Bulyk Cell reports 3 (4), 1093-1104, 2013 | 377 | 2013 |
DNAshape: a method for the high-throughput prediction of DNA structural features on a genomic scale T Zhou, L Yang, Y Lu, I Dror, AC Dantas Machado, T Ghane, R Di Felice, ... Nucleic acids research 41 (W1), W56-W62, 2013 | 338 | 2013 |
Deconvolving the recognition of DNA shape from sequence N Abe, I Dror, L Yang, M Slattery, T Zhou, HJ Bussemaker, R Rohs, ... Cell 161 (2), 307-318, 2015 | 206 | 2015 |
A widespread role of the motif environment in transcription factor binding across diverse protein families I Dror, T Golan, C Levy, R Rohs, Y Mandel-Gutfreund Genome research 25 (9), 1268-1280, 2015 | 170 | 2015 |
TFBSshape: a motif database for DNA shape features of transcription factor binding sites L Yang, T Zhou, I Dror, A Mathelier, WW Wasserman, R Gordân, R Rohs Nucleic acids research 42 (D1), D148-D155, 2014 | 140 | 2014 |
SFmap: a web server for motif analysis and prediction of splicing factor binding sites I Paz, M Akerman, I Dror, I Kosti, Y Mandel-Gutfreund Nucleic acids research 38 (suppl_2), W281-W285, 2010 | 112 | 2010 |
Xist nucleates local protein gradients to propagate silencing across the X chromosome Y Markaki, JG Chong, Y Wang, EC Jacobson, C Luong, SYX Tan, ... Cell 184 (25), 6174-6192. e32, 2021 | 101 | 2021 |
Sequences flanking the core-binding site modulate glucocorticoid receptor structure and activity S Schöne, M Jurk, MB Helabad, I Dror, I Lebars, B Kieffer, P Imhof, ... Nature communications 7 (1), 12621, 2016 | 72 | 2016 |
How motif environment influences transcription factor search dynamics: Finding a needle in a haystack I Dror, R Rohs, Y Mandel‐Gutfreund BioEssays 38 (7), 605-612, 2016 | 63 | 2016 |
Female human primordial germ cells display X-chromosome dosage compensation despite the absence of X-inactivation T Chitiashvili, I Dror, R Kim, FM Hsu, R Chaudhari, E Pandolfi, D Chen, ... Nature cell biology 22 (12), 1436-1446, 2020 | 58 | 2020 |
Covariation between homeodomain transcription factors and the shape of their DNA binding sites I Dror, T Zhou, Y Mandel-Gutfreund, R Rohs Nucleic acids research 42 (1), 430-441, 2014 | 56 | 2014 |
UV-protection timer controls linkage between stress and pigmentation skin protection systems H Malcov-Brog, A Alpert, T Golan, S Parikh, A Nordlinger, F Netti, ... Molecular Cell 72 (3), 444-456. e7, 2018 | 42 | 2018 |
XIST directly regulates X-linked and autosomal genes in naive human pluripotent cells I Dror, T Chitiashvili, SYX Tan, CT Cano, A Sahakyan, Y Markaki, ... Cell 187 (1), 110-129. e31, 2024 | 15 | 2024 |
Predicting nucleic acid binding interfaces from structural models of proteins I Dror, S Shazman, S Mukherjee, Y Zhang, F Glaser, Y Mandel‐Gutfreund Proteins: Structure, Function, and Bioinformatics 80 (2), 482-489, 2012 | 13 | 2012 |
Xist-seeded nucleation sites form local concentration gradients of silencing proteins to inactivate the X-chromosome Y Markaki, JG Chong, C Luong, SYX Tan, Y Wang, EC Jacobson, ... BioRxiv, 2020.11. 22.393546, 2020 | 11 | 2020 |
Proteopedia: 3D visualization and annotation of transcription factor–DNA readout modes ACD Machado, SB Saleebyan, BT Holmes, M Karelina, J Tam, SY Kim, ... Biochemistry and Molecular Biology Education 40 (6), 400-401, 2012 | 11 | 2012 |
FGFR3 is expressed by human primordial germ cells and is repressed after meiotic initiation to form primordial oocytes T Chitiashvili, F Hsu, I Dror, K Plath, A Clark Stem cell reports 17 (6), 1268-1278, 2022 | 8 | 2022 |
OCT4 impedes cell fate redirection by the melanocyte lineage master regulator MITF in mouse ESCs D Sheinboim, I Maza, I Dror, S Parikh, V Krupalnik, RE Bell, A Zviran, ... Nature Communications 8 (1), 1022, 2017 | 5 | 2017 |
Ataxia telangiectasia mutated signaling delays skin pigmentation upon UV exposure by mediating MITF function toward DNA repair mode N Elkoshi, S Parikh, H Malcov-Brog, R Parikh, P Manich, F Netti, A Maliah, ... Journal of Investigative Dermatology 143 (12), 2494-2506. e4, 2023 | 3 | 2023 |