Sequence determinants of intracellular phase separation by complex coacervation of a disordered protein CW Pak, M Kosno, AS Holehouse, SB Padrick, A Mittal, R Ali, AA Yunus, ... Molecular cell 63 (1), 72-85, 2016 | 551 | 2016 |
Ebola virus VP24 targets a unique NLS binding site on karyopherin alpha 5 to selectively compete with nuclear import of phosphorylated STAT1 W Xu, MR Edwards, DM Borek, AR Feagins, A Mittal, JB Alinger, KN Berry, ... Cell host & microbe 16 (2), 187-200, 2014 | 237 | 2014 |
Conserved interdomain linker promotes phase separation of the multivalent adaptor protein Nck S Banjade, Q Wu, A Mittal, WB Peeples, RV Pappu, MK Rosen Proceedings of the National Academy of Sciences 112 (47), E6426-E6435, 2015 | 156 | 2015 |
Intrinsically disordered C-terminal tails of E. coli single-stranded DNA binding protein regulate cooperative binding to single-stranded DNA AG Kozlov, E Weiland, A Mittal, V Waldman, E Antony, N Fazio, RV Pappu, ... Journal of molecular biology 427 (4), 763-774, 2015 | 89 | 2015 |
Sequence-to-conformation relationships of disordered regions tethered to folded domains of proteins A Mittal, AS Holehouse, MC Cohan, RV Pappu Journal of molecular biology 430 (16), 2403-2421, 2018 | 54 | 2018 |
Identification of novel drug scaffolds for inhibition of SARS-CoV 3-Chymotrypsin-like protease using virtual and high-throughput screenings H Lee, A Mittal, K Patel, JL Gatuz, L Truong, J Torres, DC Mulhearn, ... Bioorganic & medicinal chemistry 22 (1), 167-177, 2014 | 54 | 2014 |
An intrinsically disordered linker plays a critical role in bacterial cell division PJ Buske, A Mittal, RV Pappu, PA Levin Seminars in cell & developmental biology 37, 3-10, 2015 | 48 | 2015 |
Structural basis for human respiratory syncytial virus NS1-mediated modulation of host responses S Chatterjee, P Luthra, E Esaulova, E Agapov, BC Yen, DM Borek, ... Nature microbiology 2 (9), 1-8, 2017 | 41 | 2017 |
Reducing agents affect inhibitory activities of compounds: results from multiple drug targets H Lee, J Torres, L Truong, R Chaudhuri, A Mittal, ME Johnson Analytical biochemistry 423 (1), 46-53, 2012 | 40 | 2012 |
Mechanical signaling on the single protein level studied using steered molecular dynamics GZ Genchev, M Källberg, G Gürsoy, A Mittal, L Dubey, O Perisic, G Feng, ... Cell biochemistry and biophysics 55, 141-152, 2009 | 37 | 2009 |
Recurrent abortions in Asian Indians: no role of factor V Leiden Hong Kong/Cambridge mutation and MTHFR polymorphism A Biswas, P Choudhry, A Mittal, A Meena, R Ranjan, VP Choudhry, ... Clinical and Applied Thrombosis/Hemostasis 14 (1), 102-104, 2008 | 36 | 2008 |
Hamiltonian switch metropolis Monte Carlo simulations for improved conformational sampling of intrinsically disordered regions tethered to ordered domains of proteins A Mittal, N Lyle, TS Harmon, RV Pappu Journal of chemical theory and computation 10 (8), 3550-3562, 2014 | 33 | 2014 |
KAP-1 Promotes Resection of Broken DNA Ends Not Protected by γ-H2AX and 53BP1 in G1-Phase Lymphocytes AT Tubbs, Y Dorsett, E Chan, B Helmink, BS Lee, P Hung, R George, ... Molecular and cellular biology 34 (15), 2811-2821, 2014 | 24 | 2014 |
A custom genotyping array reveals population-level heterogeneity for the genetic risks of prostate cancer and other cancers in Africa M Harlemon, O Ajayi, P Kachambwa, MS Kim, CN Simonti, MH Quiver, ... Cancer research 80 (13), 2956-2966, 2020 | 23 | 2020 |
Glutamate racemase dimerization inhibits dynamic conformational flexibility and reduces catalytic rates S Mehboob, L Guo, W Fu, A Mittal, T Yau, K Truong, M Johlfs, F Long, ... Biochemistry 48 (29), 7045-7055, 2009 | 20 | 2009 |
Pregnancy-induced changes in systemic gene expression among healthy women and women with rheumatoid arthritis A Mittal, L Pachter, JL Nelson, H Kjærgaard, MK Smed, VL Gildengorin, ... PloS one 10 (12), e0145204, 2015 | 16 | 2015 |
How is functional specificity achieved through disordered regions of proteins? RK Das, A Mittal, RV Pappu Bioessays 35 (1), 17-22, 2013 | 16 | 2013 |
ABSINTH implicit solvation model and force field paradigm for use in simulations of intrinsically disordered proteins A Mittal, RK Das, A Vitalis, RV Pappu Computational Approaches to Protein Dynamics: From Quantum to Coarse-Grained …, 2015 | 7 | 2015 |
South Asian Patient Population Genetics Reveal Strong Founder Effects and High Rates of Homozygosity–New Resources for Precision Medicine JD Wall, JF Sathirapongsasuti, R Gupta, A Barik, RK Rai, A Rasheed, ... bioRxiv, 2020.10. 02.323238, 2020 | 4 | 2020 |
ABSINTH Implicit Solvation Model and Force Field Paradigm for Use in Simulations of Intrinsically Disordered Proteins A Mittal, RK Das, A Vitalis, RV Pappu Computational Approaches to Protein Dynamics, 208-231, 2014 | 4 | 2014 |