Sequence determinants of intracellular phase separation by complex coacervation of a disordered protein CW Pak, M Kosno, AS Holehouse, SB Padrick, A Mittal, R Ali, AA Yunus, ... Molecular cell 63 (1), 72-85, 2016 | 743 | 2016 |
Ebola virus VP24 targets a unique NLS binding site on karyopherin alpha 5 to selectively compete with nuclear import of phosphorylated STAT1 W Xu, MR Edwards, DM Borek, AR Feagins, A Mittal, JB Alinger, KN Berry, ... Cell host & microbe 16 (2), 187-200, 2014 | 260 | 2014 |
Conserved interdomain linker promotes phase separation of the multivalent adaptor protein Nck S Banjade, Q Wu, A Mittal, WB Peeples, RV Pappu, MK Rosen Proceedings of the National Academy of Sciences 112 (47), E6426-E6435, 2015 | 197 | 2015 |
The Intrinsically Disordered C-terminal Tails of E. coli Single-Stranded DNA Binding Protein Regulate Cooperative Binding to Single-Stranded DNA AG Kozlov, E Weiland, A Mittal, V Waldman, RV Pappu, LM Timothy Biophysical Journal 108 (2), 389a, 2015 | 109 | 2015 |
Sequence-to-conformation relationships of disordered regions tethered to folded domains of proteins A Mittal, AS Holehouse, MC Cohan, RV Pappu Journal of molecular biology 430 (16), 2403-2421, 2018 | 71 | 2018 |
Identification of novel drug scaffolds for inhibition of SARS-CoV 3-Chymotrypsin-like protease using virtual and high-throughput screenings H Lee, A Mittal, K Patel, JL Gatuz, L Truong, J Torres, DC Mulhearn, ... Bioorganic & medicinal chemistry 22 (1), 167-177, 2014 | 68 | 2014 |
An intrinsically disordered linker plays a critical role in bacterial cell division PJ Buske, A Mittal, RV Pappu, PA Levin Seminars in cell & developmental biology 37, 3-10, 2015 | 53 | 2015 |
Structural basis for human respiratory syncytial virus NS1-mediated modulation of host responses S Chatterjee, P Luthra, E Esaulova, E Agapov, BC Yen, DM Borek, ... Nature microbiology 2 (9), 1-8, 2017 | 51 | 2017 |
Reducing agents affect inhibitory activities of compounds: results from multiple drug targets H Lee, J Torres, L Truong, R Chaudhuri, A Mittal, ME Johnson Analytical biochemistry 423 (1), 46-53, 2012 | 48 | 2012 |
Mechanical signaling on the single protein level studied using steered molecular dynamics GZ Genchev, M Källberg, G Gürsoy, A Mittal, L Dubey, O Perisic, G Feng, ... Cell biochemistry and biophysics 55, 141-152, 2009 | 40 | 2009 |
Hamiltonian switch metropolis Monte Carlo simulations for improved conformational sampling of intrinsically disordered regions tethered to ordered domains of proteins A Mittal, N Lyle, TS Harmon, RV Pappu Journal of chemical theory and computation 10 (8), 3550-3562, 2014 | 39 | 2014 |
Recurrent abortions in Asian Indians: no role of factor V Leiden Hong Kong/Cambridge mutation and MTHFR polymorphism A Biswas, P Choudhry, A Mittal, A Meena, R Ranjan, VP Choudhry, ... Clinical and Applied Thrombosis/Hemostasis 14 (1), 102-104, 2008 | 37 | 2008 |
A custom genotyping array reveals population-level heterogeneity for the genetic risks of prostate cancer and other cancers in Africa M Harlemon, O Ajayi, P Kachambwa, MS Kim, CN Simonti, MH Quiver, ... Cancer research 80 (13), 2956-2966, 2020 | 33 | 2020 |
KAP-1 promotes resection of broken DNA ends not protected by γ-H2AX and 53BP1 in G1-phase lymphocytes AT Tubbs, Y Dorsett, E Chan, B Helmink, BS Lee, P Hung, R George, ... Molecular and cellular biology, 2014 | 28 | 2014 |
Glutamate racemase dimerization inhibits dynamic conformational flexibility and reduces catalytic rates S Mehboob, L Guo, W Fu, A Mittal, T Yau, K Truong, M Johlfs, F Long, ... Biochemistry 48 (29), 7045-7055, 2009 | 23 | 2009 |
Pregnancy-induced changes in systemic gene expression among healthy women and women with rheumatoid arthritis A Mittal, L Pachter, JL Nelson, H Kjærgaard, MK Smed, VL Gildengorin, ... PloS one 10 (12), e0145204, 2015 | 21 | 2015 |
South Asian medical cohorts reveal strong founder effects and high rates of homozygosity JD Wall, JF Sathirapongsasuti, R Gupta, A Rasheed, R Venkatesan, ... Nature communications 14 (1), 3377, 2023 | 18 | 2023 |
How is functional specificity achieved through disordered regions of proteins? RK Das, A Mittal, RV Pappu Bioessays 35 (1), 17-22, 2013 | 16 | 2013 |
ABSINTH implicit solvation model and force field paradigm for use in simulations of intrinsically disordered proteins A Mittal, R Das, A Vitalis, RV Pappu Computational Approaches to Protein Dynamics: From Quantum to Coarse-Grained …, 2014 | 11 | 2014 |
South Asian Patient Population Genetics Reveal Strong Founder Effects and High Rates of Homozygosity–New Resources for Precision Medicine JD Wall, JF Sathirapongsasuti, R Gupta, A Barik, RK Rai, A Rasheed, ... bioRxiv, 2020.10. 02.323238, 2020 | 5 | 2020 |