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Michael Ominsky
Michael Ominsky
Director Clinical Development, Ultragenyx
Verified email at umich.edu - Homepage
Title
Cited by
Cited by
Year
Dickkopf-1 is a master regulator of joint remodeling
D Diarra, M Stolina, K Polzer, J Zwerina, MS Ominsky, D Dwyer, A Korb, ...
Nature medicine 13 (2), 156-163, 2007
16182007
Targeted deletion of the sclerostin gene in mice results in increased bone formation and bone strength
X Li, MS Ominsky, QT Niu, N Sun, B Daugherty, D D'Agostin, C Kurahara, ...
Journal of Bone and Mineral Research 23 (6), 860-869, 2008
11062008
Sclerostin antibody treatment increases bone formation, bone mass, and bone strength in a rat model of postmenopausal osteoporosis
X Li, MS Ominsky, KS Warmington, S Morony, J Gong, J Cao, Y Gao, ...
Journal of Bone and Mineral Research 24 (4), 578-588, 2009
9552009
Dkk1-mediated inhibition of Wnt signaling in bone results in osteopenia
J Li, I Sarosi, RC Cattley, J Pretorius, F Asuncion, M Grisanti, S Morony, ...
Bone 39 (4), 754-766, 2006
5442006
Two doses of sclerostin antibody in cynomolgus monkeys increases bone formation, bone mineral density, and bone strength
MS Ominsky, F Vlasseros, J Jolette, SY Smith, B Stouch, G Doellgast, ...
Journal of Bone and Mineral Research 25 (5), 948-959, 2010
5382010
Denosumab, a fully human monoclonal antibody to RANKL, inhibits bone resorption and increases BMD in knock‐in mice that express chimeric (murine/human) RANKL
PJ Kostenuik, HQ Nguyen, J McCabe, KS Warmington, C Kurahara, ...
Journal of Bone and Mineral Research 24 (2), 182-195, 2009
5022009
Sclerostin and Dickkopf-1 as therapeutic targets in bone diseases
HZ Ke, WG Richards, X Li, MS Ominsky
Endocrine reviews 33 (5), 747-783, 2012
4662012
Inhibition of sclerostin by monoclonal antibody enhances bone healing and improves bone density and strength of nonfractured bones
MS Ominsky, C Li, X Li, HL Tan, E Lee, M Barrero, FJ Asuncion, D Dwyer, ...
Journal of Bone and Mineral Research 26 (5), 1012-1021, 2011
3002011
Inhibition of sclerostin by monoclonal antibody increases bone formation, bone mass, and bone strength in aged male rats
X Li, KS Warmington, QT Niu, FJ Asuncion, M Barrero, M Grisanti, ...
Journal of Bone and Mineral Research 25 (12), 2647-2656, 2010
2852010
Comparison of effects of the bisphosphonate alendronate versus the RANKL inhibitor denosumab on murine fracture healing
LC Gerstenfeld, DJ Sacks, M Pelis, ZD Mason, DT Graves, M Barrero, ...
Journal of bone and mineral research 24 (2), 196-208, 2009
2752009
Effects of denosumab on bone histomorphometry: the FREEDOM and STAND studies
IR Reid, PD Miller, JP Brown, DL Kendler, A Fahrleitner‐Pammer, I Valter, ...
Journal of Bone and Mineral Research 25 (10), 2256-2265, 2010
2632010
Neutralisation of Dkk-1 protects from systemic bone loss during inflammation and reduces sclerostin expression
GR Heiland, K Zwerina, W Baum, T Kireva, JH Distler, M Grisanti, ...
Annals of the rheumatic diseases 69 (12), 2152-2159, 2010
2522010
A bispecific antibody targeting sclerostin and DKK-1 promotes bone mass accrual and fracture repair
M Florio, K Gunasekaran, M Stolina, X Li, L Liu, B Tipton, ...
Nature communications 7 (1), 11505, 2016
2352016
RANKL inhibition with osteoprotegerin increases bone strength by improving cortical and trabecular bone architecture in ovariectomized rats
MS Ominsky, X Li, FJ Asuncion, M Barrero, KS Warmington, D Dwyer, ...
Journal of Bone and Mineral Research 23 (5), 672-682, 2008
1662008
Tissue‐level mechanisms responsible for the increase in bone formation and bone volume by sclerostin antibody
MS Ominsky, QT Niu, C Li, X Li, HZ Ke
Journal of Bone and Mineral Research 29 (6), 1424-1430, 2014
1582014
Sclerostin antibody treatment improves bone mass, bone strength, and bone defect regeneration in rats with type 2 diabetes mellitus
C Hamann, M Rauner, Y Höhna, R Bernhardt, J Mettelsiefen, C Goettsch, ...
Journal of Bone and Mineral Research 28 (3), 627-638, 2013
1392013
Sclerostin antibody improves skeletal parameters in a Brtl/+ mouse model of osteogenesis imperfecta
BP Sinder, MM Eddy, MS Ominsky, MS Caird, JC Marini, KM Kozloff
Journal of Bone and Mineral Research 28 (1), 73-80, 2013
1392013
RANKL is a marker and mediator of local and systemic bone loss in two rat models of inflammatory arthritis
M Stolina, S Adamu, M Ominsky, D Dwyer, F Asuncion, Z Geng, ...
Journal of Bone and Mineral Research 20 (10), 1756-1765, 2005
1302005
Effects of sclerostin antibodies in animal models of osteoporosis
MS Ominsky, RW Boyce, X Li, HZ Ke
Bone 96, 63-75, 2017
1292017
Dickkopf‐1 regulates bone formation in young growing rodents and upon traumatic injury
X Li, M Grisanti, W Fan, FJ Asuncion, HL Tan, D Dwyer, CY Han, L Yu, ...
Journal of Bone and Mineral Research 26 (11), 2610-2621, 2011
1292011
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