Transcriptional regulation by calcium, calcineurin, and NFAT PG Hogan, L Chen, J Nardone, A Rao Genes & development 17 (18), 2205-2232, 2003 | 2517 | 2003 |
FOXP3 controls regulatory T cell function through cooperation with NFAT Y Wu, M Borde, V Heissmeyer, M Feuerer, AD Lapan, JC Stroud, ... Cell 126 (2), 375-387, 2006 | 1506 | 2006 |
DNA binding site sequence directs glucocorticoid receptor structure and activity SH Meijsing, MA Pufall, AY So, DL Bates, L Chen, KR Yamamoto Science 324 (5925), 407-410, 2009 | 794 | 2009 |
Structure of the DNA-binding domains from NFAT, Fos and Jun bound specifically to DNA L Chen, JN Glover, PG Hogan, A Rao, SC Harrison Nature 392 (6671), 42-48, 1998 | 670 | 1998 |
Genome architectures revealed by tethered chromosome conformation capture and population-based modeling R Kalhor, H Tjong, N Jayathilaka, F Alber, L Chen Nature biotechnology 30 (1), 90-98, 2012 | 648 | 2012 |
Crystal structure of the extracellular domain of nAChR α1 bound to α-bungarotoxin at 1.94 Å resolution CD Dellisanti, Y Yao, JC Stroud, ZZ Wang, L Chen Nature neuroscience 10 (8), 953-962, 2007 | 500 | 2007 |
The crystal structure of Haelll methyltransferase covalently complexed to DNA: An extrahelical cytosine and rearranged base pairing KM Reinisch, L Chen, GL Verdine, WN Lipscomb Cell 82 (1), 143-153, 1995 | 495 | 1995 |
Docking motif interactions in MAP kinases revealed by hydrogen exchange mass spectrometry T Lee, AN Hoofnagle, Y Kabuyama, J Stroud, X Min, EJ Goldsmith, ... Molecular cell 14 (1), 43-55, 2004 | 334 | 2004 |
Direct identification of the active-site nucleophile in a DNA (cytosine-5)-methyltransferase L Chen, AM MacMillan, W Chang, K Ezaz-Nikpay, WS Lane, GL Verdine Biochemistry 30 (46), 11018-11025, 1991 | 322 | 1991 |
Structure of the forkhead domain of FOXP2 bound to DNA JC Stroud, Y Wu, DL Bates, A Han, K Nowick, S Paabo, H Tong, L Chen Structure 14 (1), 159-166, 2006 | 249 | 2006 |
Physical tethering and volume exclusion determine higher-order genome organization in budding yeast H Tjong, K Gong, L Chen, F Alber Genome research 22 (7), 1295-1305, 2012 | 232 | 2012 |
Ligand-binding domain of an α7-nicotinic receptor chimera and its complex with agonist SX Li, S Huang, N Bren, K Noridomi, CD Dellisanti, SM Sine, L Chen Nature neuroscience 14 (10), 1253-1259, 2011 | 222 | 2011 |
Population-based 3D genome structure analysis reveals driving forces in spatial genome organization H Tjong, W Li, R Kalhor, C Dai, S Hao, K Gong, Y Zhou, H Li, XJ Zhou, ... Proceedings of the National Academy of Sciences 113 (12), E1663-E1672, 2016 | 192 | 2016 |
Mechanistic insights revealed by the crystal structure of a histidine kinase with signal transducer and sensor domains C Wang, J Sang, J Wang, M Su, JS Downey, Q Wu, S Wang, Y Cai, X Xu, ... PLoS biology 11 (2), e1001493, 2013 | 186 | 2013 |
Structure of a domain-swapped FOXP3 dimer on DNA and its function in regulatory T cells HS Bandukwala, Y Wu, M Feuerer, Y Chen, B Barboza, S Ghosh, ... Immunity 34 (4), 479-491, 2011 | 184 | 2011 |
A distal enhancer in the interferon-γ (IFN-γ) locus revealed by genome sequence comparison DU Lee, O Avni, L Chen, A Rao Journal of Biological Chemistry 279 (6), 4802-4810, 2004 | 183 | 2004 |
Crystal structure of the p53 core domain bound to a full consensus site as a self-assembled tetramer Y Chen, R Dey, L Chen Structure 18 (2), 246-256, 2010 | 171 | 2010 |
Species-specific deamidation of cGAS by herpes simplex virus UL37 protein facilitates viral replication J Zhang, J Zhao, S Xu, J Li, S He, Y Zeng, L Xie, N Xie, T Liu, K Lee, ... Cell host & microbe 24 (2), 234-248. e5, 2018 | 166 | 2018 |
Mechanism of recruitment of class II histone deacetylases by myocyte enhancer factor-2 A Han, J He, Y Wu, JO Liu, L Chen Journal of molecular biology 345 (1), 91-102, 2005 | 151 | 2005 |
Structure of a TonEBP–DNA complex reveals DNA encircled by a transcription factor JC Stroud, C Lopez-Rodriguez, A Rao, L Chen Nature structural biology 9 (2), 90-94, 2002 | 151 | 2002 |