| Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors TR Wilson, J Fridlyand, Y Yan, E Penuel, L Burton, E Chan, J Peng, E Lin, ... Nature 487 (7408), 505-509, 2012 | 1318 | 2012 |
| A comprehensive genetic map of the mouse genome WF Dietrich, J Miller, R Steen, MA Merchant, D Damron-Boles, Z Husain, ... Nature 380 (6570), 149-152, 1996 | 1078 | 1996 |
| A genetic map of the mouse with 4,006 simple sequence length polymorphisms WF Dietrich, JC Miller, RG Steen, M Merchant, D Damron, R Nahf, ... Nature genetics 7 (Suppl 2), 220-245, 1994 | 708 | 1994 |
| A novel one-armed anti-c-Met antibody inhibits glioblastoma growth in vivo T Martens, NO Schmidt, C Eckerich, R Fillbrandt, M Merchant, R Schwall, ... Clinical cancer research 12 (20), 6144-6152, 2006 | 420 | 2006 |
| Oncogenic ERBB3 mutations in human cancers BS Jaiswal, NM Kljavin, EW Stawiski, E Chan, C Parikh, S Durinck, ... Cancer cell 23 (5), 603-617, 2013 | 401 | 2013 |
| Metabolite profiling stratifies pancreatic ductal adenocarcinomas into subtypes with distinct sensitivities to metabolic inhibitors A Daemen, D Peterson, N Sahu, R McCord, X Du, B Liu, K Kowanetz, ... Proceedings of the National Academy of Sciences 112 (32), E4410-E4417, 2015 | 338 | 2015 |
| A novel tankyrase small-molecule inhibitor suppresses APC mutation–driven colorectal tumor growth T Lau, E Chan, M Callow, J Waaler, J Boggs, RA Blake, S Magnuson, ... Cancer research 73 (10), 3132-3144, 2013 | 337 | 2013 |
| Mechanism of MEK inhibition determines efficacy in mutant KRAS-versus BRAF-driven cancers G Hatzivassiliou, JR Haling, H Chen, K Song, S Price, R Heald, ... Nature 501 (7466), 232-236, 2013 | 330 | 2013 |
| Quantitative locus analysis of airway hyperresponsiveness in A/J and C57BL/6J mice GT De Sanctis, M Merchant, DR Beier, RD Dredge, JK Grobholz, ... Nature genetics 11 (2), 150-154, 1995 | 330 | 1995 |
| The cancer stem cell marker aldehyde dehydrogenase is required to maintain a drug-tolerant tumor cell subpopulation D Raha, TR Wilson, J Peng, D Peterson, P Yue, M Evangelista, C Wilson, ... Cancer research 74 (13), 3579-3590, 2014 | 320 | 2014 |
| MetMAb, the one-armed 5D5 anti-c-Met antibody, inhibits orthotopic pancreatic tumor growth and improves survival H Jin, R Yang, Z Zheng, M Romero, J Ross, H Bou-Reslan, RAD Carano, ... Cancer research 68 (11), 4360-4368, 2008 | 307 | 2008 |
| Enhancer activity requires CBP/P300 bromodomain-dependent histone H3K27 acetylation R Raisner, S Kharbanda, L Jin, E Jeng, E Chan, M Merchant, PM Haverty, ... Cell reports 24 (7), 1722-1729, 2018 | 294 | 2018 |
| Intermittent administration of MEK inhibitor GDC-0973 plus PI3K inhibitor GDC-0941 triggers robust apoptosis and tumor growth inhibition KP Hoeflich, M Merchant, C Orr, J Chan, D Den Otter, L Berry, I Kasman, ... Cancer research 72 (1), 210-219, 2012 | 272 | 2012 |
| Monovalent antibody design and mechanism of action of onartuzumab, a MET antagonist with anti-tumor activity as a therapeutic agent M Merchant, X Ma, HR Maun, Z Zheng, J Peng, M Romero, A Huang, ... Proceedings of the National Academy of Sciences 110 (32), E2987-E2996, 2013 | 260 | 2013 |
| Bispecific antibodies with natural architecture produced by co-culture of bacteria expressing two distinct half-antibodies C Spiess, M Merchant, A Huang, Z Zheng, NY Yang, J Peng, D Ellerman, ... Nature biotechnology 31 (8), 753-758, 2013 | 216 | 2013 |
| Network quantification of EGFR signaling unveils potential for targeted combination therapy B Klinger, A Sieber, R Fritsche‐Guenther, F Witzel, L Berry, ... Molecular systems biology 9 (1), 673, 2013 | 169 | 2013 |
| The LMP2A ITAM is essential for providing B cells with development and survival signals in vivo M Merchant, RG Caldwell, R Longnecker Journal of virology 74 (19), 9115-9124, 2000 | 159 | 2000 |
| A transgene insertion creating a heritable chromosome deletion mouse model of Prader-Willi and Angelman syndromes JM Gabriel, M Merchant, T Ohta, Y Ji, RG Caldwell, MJ Ramsey, ... Proceedings of the National Academy of Sciences 96 (16), 9258-9263, 1999 | 152 | 1999 |
| Suppressor of fused regulates Gli activity through a dual binding mechanism M Merchant, FF Vajdos, M Ultsch, HR Maun, U Wendt, J Cannon, ... Molecular and cellular biology 24 (19), 8627-8641, 2004 | 147 | 2004 |
| Discovery of (S)-1-(1-(4-Chloro-3-fluorophenyl)-2-hydroxyethyl)-4-(2-((1-methyl-1H-pyrazol-5-yl)amino)pyrimidin-4-yl)pyridin-2(1H)-one (GDC-0994), an … JF Blake, M Burkard, J Chan, H Chen, KJ Chou, D Diaz, DA Dudley, ... Journal of medicinal chemistry 59 (12), 5650-5660, 2016 | 140 | 2016 |
