The Warburg effect and drug resistance B Bhattacharya, MF Mohd Omar, R Soong British journal of pharmacology 173 (6), 970-979, 2016 | 261 | 2016 |
Increased drug resistance is associated with reduced glucose levels and an enhanced glycolysis phenotype B Bhattacharya, SHH Low, C Soh, N Kamal Mustapa, ... British journal of pharmacology 171 (13), 3255-3267, 2014 | 93 | 2014 |
Clinical and therapeutic relevance of PIM1 kinase in gastric cancer B Yan, EX Yau, S Samanta, CW Ong, KJ Yong, LK Ng, B Bhattacharya, ... Gastric Cancer 15, 188-197, 2012 | 40 | 2012 |
Pharmacologic synergy between dual phosphoinositide-3-kinase and mammalian target of rapamycin inhibition and 5-fluorouracil in PIK3CA mutant gastric cancer cells B Bhattacharya, M Akram, I Balasubramanian, KKY Tam, KX Koh, MQ Yee, ... Cancer biology & therapy 13 (1), 34-42, 2012 | 37 | 2012 |
Enhancement of α2‐adrenoceptor‐mediated vasoconstriction by the thromboxane‐mimetic U46619 in the porcine isolated ear artery: role of the ERK–MAP kinase … B Bhattacharya, RE Roberts British journal of pharmacology 139 (1), 156-162, 2003 | 30 | 2003 |
Acquired resistance to PI3K/mTOR inhibition is associated with mitochondrial DNA mutation and glycolysis KX Koh, GH Tan, SHH Low, MFM Omar, MJ Han, B Iacopetta, R Soo, ... Oncotarget 8 (66), 110133, 2017 | 22 | 2017 |
Low cytosine triphosphate synthase 2 expression renders resistance to 5-fluorouracil in colorectal cancer WL Tan, B Bhattacharya, M Loh, I Balasubramanian, M Akram, D Dong, ... Cancer biology & therapy 11 (6), 599-608, 2011 | 17 | 2011 |
Role of cytosolic phospholipase A2 in the enhancement of α2-adrenoceptor-mediated vasoconstriction by the thromboxane-mimetic U46619 in the porcine isolated ear artery … B Bhattacharya, R Williams, ML Latif, RE Roberts Biochemical pharmacology 70 (8), 1200-1210, 2005 | 9 | 2005 |
Effect of cell microenvironment on the drug sensitivity of hepatocellular cancer cells B Bhattacharya, DQ Huang, SHH Low, GH Tan, MJ Han, S Singh, B Tang, ... Oncotarget 12 (7), 674, 2021 | 4 | 2021 |
Acquired resistance to combination treatment through loss of synergy with MEK and PI3K inhibitors in colorectal cancer B Bhattacharya, SHH Low, ML Chong, D Chia, KX Koh, NS Sapari, ... Oncotarget 7 (20), 29187, 2016 | 4 | 2016 |
Activity of BAY1082439, a balanced PI3Kα/β inhibitor, in gastric cancer HT Hung, R Ong, K Haike, E Petrova, ML Chong, M Loh, B Bhattacharya, ... Cancer Research 75 (15_Supplement), 2674-2674, 2015 | 1 | 2015 |
Abstract B52: Bioenergetic switch confers acquired resistance to BEZ235 in EGFR T790M-mutant non-small cell lung cancer B Bhattacharya, KX Koh, MF Mohamed Omar, S Low, J Tan, NS Sapari, ... Molecular Cancer Therapeutics 14 (12_Supplement_2), B52-B52, 2015 | | 2015 |
Determinants of sensitivity to PI3K inhibitors in PIK3CA wildtype gastric tumor cells ML Chong, B Bhattacharya, D Voon, KX Koh, HH Low, TL Chang, M Wu, ... Cancer Research 75 (15_Supplement), 2655-2655, 2015 | | 2015 |
Abstract B02: Determinants of acquired resistance to combination treatment with MEK and PI3K inhibitors B Bhattacharya, S Low, D Chia, KX Koh, ML Chong, T Benoukraf, ... Clinical Cancer Research 21 (4_Supplement), B02-B02, 2015 | | 2015 |
74 Increased EDN1 expression mediates acquired resistance to the combination therapy of PI3K and MEK inhibitors for colorectal cancer B Bhattacharya, SHH Low, T Benoukraf, ML Chong, KX Koh, R Soong European Journal of Cancer, 29, 2014 | | 2014 |
Determinants of acquired resistance to PI3K/mTOR inhibition in cells refractory to EGFR inhibition. KX Koh, B Bhattacharya, J Loh, HK Ng, R Soo, B Iacopetta, R Soong Cancer Research 73 (8_Supplement), 5650-5650, 2013 | | 2013 |
Attenuation of hypoglycemia-associated resistance to PI103 and KU63794 through their synergistic combination in PIK3CA-mutant gastric cancer cells. B Bhattacharya, S Low, M Yee, KX Koh, R Soong Cancer Research 73 (8_Supplement), 959-959, 2013 | | 2013 |
320 Enhancement of 5 fluorouracil (5FU)-mediated cytotoxicity in human gastric cancer (GC) cells by the phosphatidylinositol 3-kinase (PI3K) inhibitor, PI103, via thymidylate … B Bhattacharya, M Akram, I Balasubramanian, R Soong Ejc Supplements 7 (8), 102, 2010 | | 2010 |
Direct inhibition of mTOR may be detrimental when combining mTOR inhibitors or dual PI3 kinase/mTOR inhibitors with paclitaxel B Bhattacharya, A Richardson, N Sain, M Ormerod, S Kaye, P Workman, ... Cancer Research 68 (9_Supplement), 4180-4180, 2008 | | 2008 |
Inhibitors of phosphoinositide 3-kinase (PI3K)/AKT pathway in combination with cytotoxic drugs in human ovarian cancer cell lines B Bhattacharya Royal Holloway, University of London, 2008 | | 2008 |