Nuclear organization of active and inactive chromatin domains uncovered by chromosome conformation capture–on-chip (4C) M Simonis, P Klous, E Splinter, Y Moshkin, R Willemsen, E De Wit, ... Nature genetics 38 (11), 1348-1354, 2006 | 1592 | 2006 |
A decade of 3C technologies: insights into nuclear organization E De Wit, W De Laat Genes & development 26 (1), 11-24, 2012 | 882 | 2012 |
In vivo imaging reveals extracellular vesicle-mediated phenocopying of metastatic behavior A Zomer, C Maynard, FJ Verweij, A Kamermans, R Schäfer, E Beerling, ... Cell 161 (5), 1046-1057, 2015 | 808 | 2015 |
A single oncogenic enhancer rearrangement causes concomitant EVI1 and GATA2 deregulation in leukemia S Gröschel, MA Sanders, R Hoogenboezem, E de Wit, BAM Bouwman, ... Cell 157 (2), 369-381, 2014 | 671 | 2014 |
The cohesin release factor WAPL restricts chromatin loop extension JHI Haarhuis, RH van der Weide, VA Blomen, JO Yáńez-Cuna, ... Cell 169 (4), 693-707. e14, 2017 | 631 | 2017 |
CTCF binding polarity determines chromatin looping E de Wit, ESM Vos, SJB Holwerda, C Valdes-Quezada, MJAM Verstegen, ... Molecular cell 60 (4), 676-684, 2015 | 615 | 2015 |
Characterization of the Drosophila melanogaster genome at the nuclear lamina H Pickersgill, B Kalverda, E De Wit, W Talhout, M Fornerod, ... Nature genetics 38 (9), 1005-1014, 2006 | 612 | 2006 |
eRNAs are required for p53-dependent enhancer activity and gene transcription CA Melo, J Drost, PJ Wijchers, H van de Werken, E de Wit, JAFO Vrielink, ... Molecular cell 49 (3), 524-535, 2013 | 558 | 2013 |
Genome-wide profiling of PRC1 and PRC2 Polycomb chromatin binding in Drosophila melanogaster B Tolhuis, I Muijrers, E de Wit, H Teunissen, W Talhout, B van Steensel, ... Nature genetics 38 (6), 694-699, 2006 | 431 | 2006 |
Robust 4C-seq data analysis to screen for regulatory DNA interactions HJG Van De Werken, G Landan, SJB Holwerda, M Hoichman, P Klous, ... Nature methods 9 (10), 969-972, 2012 | 425 | 2012 |
Prospero acts as a binary switch between self-renewal and differentiation in Drosophila neural stem cells SP Choksi, TD Southall, T Bossing, K Edoff, E de Wit, BE Fischer, ... Developmental cell 11 (6), 775-789, 2006 | 421 | 2006 |
The inactive X chromosome adopts a unique three-dimensional conformation that is dependent on Xist RNA E Splinter, E de Wit, EP Nora, P Klous, HJG van de Werken, Y Zhu, ... Genes & development 25 (13), 1371-1383, 2011 | 374 | 2011 |
Limitations and possibilities of small RNA digital gene expression profiling SEV Linsen, E de Wit, G Janssens, S Heater, L Chapman, RK Parkin, ... Nature methods 6 (7), 474-476, 2009 | 343 | 2009 |
Plasticity between epithelial and mesenchymal states unlinks EMT from metastasis-enhancing stem cell capacity E Beerling, D Seinstra, E de Wit, L Kester, D van der Velden, C Maynard, ... Cell reports 14 (10), 2281-2288, 2016 | 322 | 2016 |
The pluripotent genome in three dimensions is shaped around pluripotency factors E De Wit, BAM Bouwman, Y Zhu, P Klous, E Splinter, MJAM Verstegen, ... Nature 501 (7466), 227-231, 2013 | 272 | 2013 |
The structural basis for cohesin–CTCF-anchored loops Y Li, JHI Haarhuis, Á Sedeńo Cacciatore, R Oldenkamp, MS van Ruiten, ... Nature 578 (7795), 472-476, 2020 | 270 | 2020 |
Targeted sequencing by proximity ligation for comprehensive variant detection and local haplotyping PJP De Vree, E De Wit, M Yilmaz, M Van De Heijning, P Klous, ... Nature biotechnology 32 (10), 1019-1025, 2014 | 257 | 2014 |
Determining long-range chromatin interactions for selected genomic sites using 4C-seq technology: from fixation to computation E Splinter, E de Wit, HJG van de Werken, P Klous, W de Laat Methods 58 (3), 221-230, 2012 | 254 | 2012 |
4C technology: protocols and data analysis HJG Van De Werken, PJP De Vree, E Splinter, SJB Holwerda, P Klous, ... Methods in enzymology 513, 89-112, 2012 | 248 | 2012 |
Hotspots of transcription factor colocalization in the genome of Drosophila melanogaster C Moorman, LV Sun, J Wang, E de Wit, W Talhout, LD Ward, F Greil, ... Proceedings of the National Academy of Sciences 103 (32), 12027-12032, 2006 | 223 | 2006 |