| Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 L Galluzzi, I Vitale, SA Aaronson, JM Abrams, D Adam, P Agostinis, ... Cell Death & Differentiation 25 (3), 486-541, 2018 | 5354 | 2018 |
| Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy PE Czabotar, G Lessene, A Strasser, JM Adams Nature reviews Molecular cell biology 15 (1), 49-63, 2014 | 3375 | 2014 |
| Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak SN Willis, JI Fletcher, T Kaufmann, MF van Delft, L Chen, PE Czabotar, ... Science 315 (5813), 856-859, 2007 | 1459 | 2007 |
| The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized MF Van Delft, AH Wei, KD Mason, CJ Vandenberg, L Chen, PE Czabotar, ... Cancer cell 10 (5), 389-399, 2006 | 1458 | 2006 |
| The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism JM Murphy, PE Czabotar, JM Hildebrand, IS Lucet, JG Zhang, ... Immunity 39 (3), 443-453, 2013 | 1139 | 2013 |
| BCL-2 family antagonists for cancer therapy G Lessene, PE Czabotar, PM Colman Nature reviews Drug discovery 7 (12), 989-1000, 2008 | 790 | 2008 |
| Molecular biology of Bax and Bak activation and action D Westphal, G Dewson, PE Czabotar, RM Kluck Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1813 (4), 521-531, 2011 | 745 | 2011 |
| Bax crystal structures reveal how BH3 domains activate Bax and nucleate its oligomerization to induce apoptosis PE Czabotar, D Westphal, G Dewson, S Ma, C Hockings, WD Fairlie, ... Cell 152 (3), 519-531, 2013 | 630 | 2013 |
| Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death JM Hildebrand, MC Tanzer, IS Lucet, SN Young, SK Spall, P Sharma, ... Proceedings of the National Academy of Sciences 111 (42), 15072-15077, 2014 | 557 | 2014 |
| Structural insights into the degradation of Mcl-1 induced by BH3 domains PE Czabotar, EF Lee, MF van Delft, CL Day, BJ Smith, DCS Huang, ... Proceedings of the National Academy of Sciences 104 (15), 6217-6222, 2007 | 505 | 2007 |
| Structure-guided design of a selective BCL-XL inhibitor G Lessene, PE Czabotar, BE Sleebs, K Zobel, KN Lowes, JM Adams, ... Nature chemical biology 9 (6), 390-397, 2013 | 422 | 2013 |
| Mechanism and inhibition of the papain‐like protease, PLpro, of SARS‐CoV‐2 T Klemm, G Ebert, DJ Calleja, CC Allison, LW Richardson, JP Bernardini, ... The EMBO journal 39 (18), e106275, 2020 | 383 | 2020 |
| Acquisition of the recurrent Gly101Val mutation in BCL2 confers resistance to venetoclax in patients with progressive chronic lymphocytic leukemia P Blombery, MA Anderson, J Gong, R Thijssen, RW Birkinshaw, ... Cancer discovery 9 (3), 342-353, 2019 | 377 | 2019 |
| The dendritic cell receptor Clec9A binds damaged cells via exposed actin filaments JG Zhang, PE Czabotar, AN Policheni, I Caminschi, S San Wan, ... Immunity 36 (4), 646-657, 2012 | 371 | 2012 |
| Crystal structure of ABT-737 complexed with Bcl-xL: implications for selectivity of antagonists of the Bcl-2 family EF Lee, PE Czabotar, BJ Smith, K Deshayes, K Zobel, PM Colman, ... Cell Death & Differentiation 14 (9), 1711-1713, 2007 | 322 | 2007 |
| Discovery of a Potent and Selective BCL-XL Inhibitor with in Vivo Activity ZF Tao, L Hasvold, L Wang, X Wang, AM Petros, CH Park, ER Boghaert, ... ACS medicinal chemistry letters 5 (10), 1088-1093, 2014 | 307 | 2014 |
| Vaccinia virus anti-apoptotic F1L is a novel Bcl-2-like domain-swapped dimer that binds a highly selective subset of BH3-containing death ligands M Kvansakul, H Yang, WD Fairlie, PE Czabotar, SF Fischer, MA Perugini, ... Cell Death & Differentiation 15 (10), 1564-1571, 2008 | 292 | 2008 |
| The BCL-2 family of proteins and mitochondrial outer membrane permeabilisation RW Birkinshaw, PE Czabotar Seminars in cell & developmental biology 72, 152-162, 2017 | 254 | 2017 |
| Bak activation for apoptosis involves oligomerization of dimers via their α6 helices G Dewson, T Kratina, P Czabotar, CL Day, JM Adams, RM Kluck Molecular cell 36 (4), 696-703, 2009 | 251 | 2009 |
| A novel BH3 ligand that selectively targets Mcl-1 reveals that apoptosis can proceed without Mcl-1 degradation EF Lee, PE Czabotar, MF Van Delft, EM Michalak, MJ Boyle, SN Willis, ... The Journal of cell biology 180 (2), 341-355, 2008 | 187 | 2008 |
