| Overexpression of Insig-1 in the livers of transgenic mice inhibits SREBP processing and reduces insulin-stimulated lipogenesis LJ Engelking, H Kuriyama, RE Hammer, JD Horton, MS Brown, ... The Journal of clinical investigation 113 (8), 1168-1175, 2004 | 302 | 2004 |
| Schoenheimer effect explained–feedback regulation of cholesterol synthesis in mice mediated by Insig proteins LJ Engelking, G Liang, RE Hammer, K Takaishi, H Kuriyama, BM Evers, ... The Journal of clinical investigation 115 (9), 2489-2498, 2005 | 258 | 2005 |
| Interplay between ChREBP and SREBP-1c coordinates postprandial glycolysis and lipogenesis in livers of mice [S] AG Linden, S Li, HY Choi, F Fang, M Fukasawa, K Uyeda, RE Hammer, ... Journal of lipid research 59 (3), 475-487, 2018 | 190 | 2018 |
| Severe facial clefting in Insig-deficient mouse embryos caused by sterol accumulation and reversed by lovastatin LJ Engelking, BM Evers, JA Richardson, JL Goldstein, MS Brown, G Liang The Journal of clinical investigation 116 (9), 2356-2365, 2006 | 98 | 2006 |
| Hypoxia-inducible factor 1α activates insulin-induced gene 2 (Insig-2) transcription for degradation of 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase in the liver S Hwang, AD Nguyen, Y Jo, LJ Engelking, J Brugarolas, ... Journal of Biological Chemistry 292 (22), 9382-9393, 2017 | 97 | 2017 |
| Compensatory increase in fatty acid synthesis in adipose tissue of mice with conditional deficiency of SCAP in liver H Kuriyama, G Liang, LJ Engelking, JD Horton, JL Goldstein, MS Brown Cell metabolism 1 (1), 41-51, 2005 | 76 | 2005 |
| Blockade of cholesterol absorption by ezetimibe reveals a complex homeostatic network in enterocytes LJ Engelking, MR McFarlane, CK Li, G Liang Journal of lipid research 53 (7), 1359-1368, 2012 | 69 | 2012 |
| Identification of BV/ODV-C42, an Autographa californica Nucleopolyhedrovirus orf101-Encoded Structural Protein Detected in Infected-Cell Complexes with ODV … SC Braunagel, PA Guidry, G Rosas-Acosta, L Engelking, MD Summers Journal of virology 75 (24), 12331-12338, 2001 | 67 | 2001 |
| Adipocyte iron levels impinge on a fat-gut crosstalk to regulate intestinal lipid absorption and mediate protection from obesity Z Zhang, JB Funcke, Z Zi, S Zhao, LG Straub, Y Zhu, Q Zhu, C Crewe, ... Cell metabolism 33 (8), 1624-1639. e9, 2021 | 57 | 2021 |
| Contribution of accelerated degradation to feedback regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase and cholesterol metabolism in the liver S Hwang, IZ Hartman, LN Calhoun, K Garland, GA Young, MA Mitsche, ... Journal of Biological Chemistry 291 (26), 13479-13494, 2016 | 44 | 2016 |
| Insig proteins mediate feedback inhibition of cholesterol synthesis in the intestine MR McFarlane, G Liang, LJ Engelking Journal of Biological Chemistry 289 (4), 2148-2156, 2014 | 42 | 2014 |
| Developmental and extrahepatic physiological functions of SREBP pathway genes in mice LJ Engelking, MJ Cantoria, Y Xu, G Liang Seminars in cell & developmental biology 81, 98-109, 2018 | 41 | 2018 |
| Scap is required for sterol synthesis and crypt growth in intestinal mucosa [S] MR McFarlane, MJ Cantoria, AG Linden, BA January, G Liang, ... Journal of lipid research 56 (8), 1560-1571, 2015 | 35 | 2015 |
| Cholesterol auxotrophy and intolerance to ezetimibe in mice with SREBP-2 deficiency in the intestine S Rong, JG McDonald, LJ Engelking Journal of lipid research 58 (10), 1988-1998, 2017 | 18 | 2017 |
| RNA sequencing unravels novel L cell constituents and mechanisms of GLP-1 secretion in human gastric bypass-operated intestine MG Miskelly, A Lindqvist, E Piccinin, A Hamilton, E Cowan, BJ Nergård, ... Diabetologia 67 (2), 356-370, 2024 | | 2024 |
| SREBPs in the control of intestinal homeostasis and tumorigenesis L Engelking Journal of Biological Chemistry 299 (3), S452, 2023 | | 2023 |
| Genetic syndromes of intestinal polyposis and cancer predisposition L Engelking | | 2020 |
| 1-Interplay between CHREBP and SREBP-1C Coordinates Postprandial Hepatic Glycolysis and Lipogenesis L Engelking, S Li, A Linden, J Horton, G Liang Gastroenterology 154 (6), S-1, 2018 | | 2018 |
| SITE-2 PROTEASE AND NON-ALCOHOLIC FATTY LIVER DISEASE Y Xu, A Calderon-Rodriguez, LJ Engelking JOURNAL OF INVESTIGATIVE MEDICINE 66 (4), 834-834, 2018 | | 2018 |
| 580 Ezetimibe Modulates Endogenous LXR Ligands to Regulate Intestinal LDLR Receptors via IDOL MR McFarlane, L Engelking Gastroenterology 5 (146), S-108, 2014 | | 2014 |
Matthew R. McFarlane, MD, PhDChief Resident, Radiation Oncology (PGY-5), University of MichiganПотвърден имейл адрес: med.umich.edu
