Следене
Kristy Horan
Kristy Horan
PhD MSc Section Leader Bioinformatics MDU-PHL at Peter Doherty Instiute
Няма потвърден имейл адрес
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Позовавания
Позовавания
Година
IFI16 is an innate immune sensor for intracellular DNA
L Unterholzner, SE Keating, M Baran, KA Horan, SB Jensen, S Sharma, ...
Nature immunology 11 (11), 997-1004, 2010
18232010
Recognition of herpesviruses by the innate immune system
SR Paludan, AG Bowie, KA Horan, KA Fitzgerald
Nature Reviews Immunology 11 (2), 143-154, 2011
4152011
Single sample scoring of molecular phenotypes
M Foroutan, DD Bhuva, R Lyu, K Horan, J Cursons, MJ Davis
BMC bioinformatics 19, 1-10, 2018
3232018
The role of the inositol polyphosphate 5-phosphatases in cellular function and human disease
LM Ooms, KA Horan, P Rahman, G Seaton, R Gurung, DS Kethesparan, ...
Biochemical Journal 419 (1), 29-49, 2009
2692009
Listeria monocytogenes induces IFNβ expression through an IFI16‐, cGAS‐ and STING‐dependent pathway
K Hansen, T Prabakaran, A Laustsen, SE Jørgensen, SH Rahbæk, ...
The EMBO journal 33 (15), 1654-1666, 2014
2652014
Virus-cell fusion as a trigger of innate immunity dependent on the adaptor STING
CK Holm, SB Jensen, MR Jakobsen, N Cheshenko, KA Horan, ...
Nature immunology 13 (8), 737-743, 2012
2562012
Proteasomal degradation of herpes simplex virus capsids in macrophages releases DNA to the cytosol for recognition by DNA sensors
KA Horan, K Hansen, MR Jakobsen, CK Holm, S Søby, L Unterholzner, ...
The Journal of Immunology 190 (5), 2311-2319, 2013
2232013
Tracking the COVID-19 pandemic in Australia using genomics
T Seemann, CR Lane, NL Sherry, S Duchene, A Gonçalves da Silva, ...
Nature communications 11 (1), 1-9, 2020
1862020
TLR3 deficiency renders astrocytes permissive to herpes simplex virus infection and facilitates establishment of CNS infection in mice
LS Reinert, L Harder, CK Holm, MB Iversen, KA Horan, ...
The Journal of clinical investigation 122 (4), 1368-1376, 2012
1862012
Genomic HIV RNA induces innate immune responses through RIG-I-dependent sensing of secondary-structured RNA
RK Berg, J Melchjorsen, J Rintahaka, E Diget, S Søby, KA Horan, ...
PloS one 7 (1), e29291, 2012
1652012
Early innate recognition of herpes simplex virus in human primary macrophages is mediated via the MDA5/MAVS-dependent and MDA5/MAVS/RNA polymerase III-independent pathways
J Melchjorsen, J Rintahaka, S Søby, KA Horan, A Poltajainen, ...
Journal of virology 84 (21), 11350-11358, 2010
1602010
HSV infection induces production of ROS, which potentiate signaling from pattern recognition receptors: role for S-glutathionylation of TRAF3 and 6
R Gonzalez-Dosal, KA Horan, SH Rahbek, H Ichijo, ZJ Chen, JJ Mieyal, ...
PLoS pathogens 7 (9), e1002250, 2011
1342011
Activation of autophagy by α-herpesviruses in myeloid cells is mediated by cytoplasmic viral DNA through a mechanism dependent on stimulator of IFN genes
SB Rasmussen, KA Horan, CK Holm, AJ Stranks, TC Mettenleiter, ...
The journal of immunology 187 (10), 5268-5276, 2011
1282011
Extracellular 2′-5′ oligoadenylate synthetase stimulates RNase L-independent antiviral activity: a novel mechanism of virus-induced innate immunity
H Kristiansen, CA Scherer, M McVean, SP Iadonato, S Vends, ...
Journal of virology 84 (22), 11898-11904, 2010
1222010
Evasion of innate cytosolic DNA sensing by a gammaherpesvirus facilitates establishment of latent infection
C Sun, SA Schattgen, P Pisitkun, JP Jorgensen, AT Hilterbrand, LJ Wang, ...
The Journal of Immunology 194 (4), 1819-1831, 2015
1092015
INPP5E regulates phosphoinositide-dependent cilia transition zone function
JM Dyson, SE Conduit, SJ Feeney, S Hakim, T DiTommaso, AJ Fulcher, ...
Journal of Cell Biology 216 (1), 247-263, 2017
1072017
Regulation of PI (3) K/Akt signalling and cellular transformation by inositol polyphosphate 4‐phosphatase‐1
I Ivetac, R Gurung, S Hakim, KA Horan, DA Sheffield, LC Binge, ...
EMBO reports 10 (5), 487-493, 2009
852009
The inositol polyphosphate 5-phosphatases: traffic controllers, waistline watchers and tumour suppressors?
MV Astle, KA Horan, LM Ooms, CA Mitchell
Biochemical Society Symposia 74, 161-181, 2007
712007
Phosphatidylinositol 3-phosphate [PtdIns (3) P] is generated at thePlasma membrane by an inositol polyphosphate 5-phosphatase: endogenous PtdIns (3) P can promote GLUT4 …
AM Kong, KA Horan, A Sriratana, CG Bailey, LJ Collyer, HH Nandurkar, ...
Molecular and cellular biology 26 (16), 6065-6081, 2006
712006
Structure guided prediction of Pyrazinamide resistance mutations in pncA
M Karmakar, CHM Rodrigues, K Horan, JT Denholm, DB Ascher
Scientific reports 10 (1), 1875, 2020
612020
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