Jun Wu
Jun Wu
Associate Professor of Physiology, University of Michigan
Потвърден имейл адрес: umich.edu
A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis
P Boström, J Wu, MP Jedrychowski, A Korde, L Ye, JC Lo, KA Rasbach, ...
Nature 481 (7382), 463-468, 2012
TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling
K Inoki, Y Li, T Zhu, J Wu, KL Guan
Nature cell biology 4 (9), 648-657, 2002
Beige adipocytes are a distinct type of thermogenic fat cell in mouse and human
J Wu, P Boström, LM Sparks, L Ye, JH Choi, AH Giang, M Khandekar, ...
Cell 150 (2), 366-376, 2012
FGF21 regulates PGC-1α and browning of white adipose tissues in adaptive thermogenesis
S Kleiner, N Douris, EC Fox, RJ Mepani, F Verdeguer, J Wu, ...
Genes & development 26 (3), 271-281, 2012
Exercise induces hippocampal BDNF through a PGC-1α/FNDC5 pathway
CD Wrann, JP White, J Salogiannnis, D Laznik-Bogoslavski, J Wu, D Ma, ...
Cell metabolism 18 (5), 649-659, 2013
From acute ER stress to physiological roles of the unfolded protein response
J Wu, RJ Kaufman
Cell Death & Differentiation 13 (3), 374-384, 2006
Adaptive thermogenesis in adipocytes: is beige the new brown?
J Wu, P Cohen, BM Spiegelman
Genes & development 27 (3), 234-250, 2013
Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response
K Zhang, X Shen, J Wu, K Sakaki, T Saunders, DT Rutkowski, SH Back, ...
Cell 124 (3), 587-599, 2006
Cold acclimation recruits human brown fat and increases nonshivering thermogenesis
AAJJ van der Lans, J Hoeks, B Brans, GHEJ Vijgen, MGW Visser, ...
The Journal of clinical investigation 123 (8), 3395-3403, 2013
Adaptation to ER stress is mediated by differential stabilities of pro-survival and pro-apoptotic mRNAs and proteins
DT Rutkowski, SM Arnold, CN Miller, J Wu, J Li, KM Gunnison, K Mori, ...
PLoS biology 4 (11), e374, 2006
Ablation of PRDM16 and beige adipose causes metabolic dysfunction and a subcutaneous to visceral fat switch
P Cohen, JD Levy, Y Zhang, A Frontini, DP Kolodin, KJ Svensson, JC Lo, ...
Cell 156 (1), 304-316, 2014
ATF6α optimizes long-term endoplasmic reticulum function to protect cells from chronic stress
J Wu, DT Rutkowski, M Dubois, J Swathirajan, T Saunders, J Wang, ...
Developmental cell 13 (3), 351-364, 2007
A PGC-1α isoform induced by resistance training regulates skeletal muscle hypertrophy
JL Ruas, JP White, RR Rao, S Kleiner, KT Brannan, BC Harrison, ...
Cell 151 (6), 1319-1331, 2012
UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators
DT Rutkowski, J Wu, SH Back, MU Callaghan, SP Ferris, J Iqbal, R Clark, ...
Developmental cell 15 (6), 829-840, 2008
C/EBPβ controls exercise-induced cardiac growth and protects against pathological cardiac remodeling
P Boström, N Mann, J Wu, PA Quintero, ER Plovie, D Panáková, ...
Cell 143 (7), 1072-1083, 2010
EBF2 determines and maintains brown adipocyte identity
S Rajakumari, J Wu, J Ishibashi, HW Lim, AH Giang, KJ Won, RR Reed, ...
Cell metabolism 17 (4), 562-574, 2013
TRPV4 is a regulator of adipose oxidative metabolism, inflammation, and energy homeostasis
L Ye, S Kleiner, J Wu, R Sah, RK Gupta, AS Banks, P Cohen, ...
Cell 151 (1), 96-110, 2012
The unfolded protein response mediates adaptation to exercise in skeletal muscle through a PGC-1α/ATF6α complex
J Wu, JL Ruas, JL Estall, KA Rasbach, JH Choi, L Ye, P Boström, HM Tyra, ...
Cell metabolism 13 (2), 160-169, 2011
Fat cells directly sense temperature to activate thermogenesis
L Ye, J Wu, P Cohen, L Kazak, MJ Khandekar, MP Jedrychowski, X Zeng, ...
Proceedings of the National Academy of Sciences 110 (30), 12480-12485, 2013
Protein kinase Cθ is required for autophagy in response to stress in the endoplasmic reticulum
K Sakaki, J Wu, RJ Kaufman
Journal of biological chemistry 283 (22), 15370-15380, 2008
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Статии 1–20