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Francisco León
Francisco León
Asistant Professor
Verified email at mailbox.sc.edu
Title
Cited by
Cited by
Year
Abuse liability and therapeutic potential of the Mitragyna speciosa (kratom) alkaloids mitragynine and 7‐hydroxymitragynine
SE Hemby, S McIntosh, F Leon, SJ Cutler, CR McCurdy
Addiction biology 24 (5), 874-885, 2019
1532019
Investigation of the adrenergic and opioid binding affinities, metabolic stability, plasma protein binding properties, and functional effects of selected indole-based kratom …
S Obeng, SH Kamble, ME Reeves, LF Restrepo, A Patel, M Behnke, ...
Journal of medicinal chemistry 63 (1), 433-439, 2019
1132019
Phytochemical Characterization of the Leaves of Mitragyna Speciosa Grown in USA
F León, E Habib, JE Adkins, EB Furr, CR McCurdy, SJ Cutler
Natural product communications 4 (7), 1934578X0900400705, 2009
1012009
Metabolite profiling and identification of enzymes responsible for the metabolism of mitragynine, the major alkaloid of Mitragyna speciosa (kratom)
SH Kamble, A Sharma, TI King, F León, CR McCurdy, BA Avery
Xenobiotica, 0
98*
Lanostanoid Triterpenes from Laetiporus s ulph u reus and Apoptosis Induction on HL-60 Human Myeloid Leukemia Cells
F León, J Quintana, A Rivera, F Estévez, J Bermejo
Journal of natural products 67 (12), 2008-2011, 2004
942004
Steroidal Saponins from the Bark of Dracaena draco and Their Cytotoxic Activities
AG González, JC Hernández, F León, JI Padrón, F Estévez, J Quintana, ...
Journal of natural products 66 (6), 793-798, 2003
942003
New Lanostanoids from the Fungus Ganoderma c oncinna
AG González, F León, A Rivera, JI Padrón, J González-Plata, JC Zuluaga, ...
Journal of natural products 65 (3), 417-421, 2002
852002
Simultaneous quantification of ten key Kratom alkaloids in Mitragyna speciosa leaf extracts and commercial products by ultra‐performance liquid chromatography …
A Sharma, SH Kamble, F León, NJY Chear, TI King, EC Berthold, ...
Drug testing and analysis 11 (8), 1162-1171, 2019
832019
Lanostanoid Triterpenes from Ganoderma l ucidum
AG González, F León, A Rivera, CM Muñoz, J Bermejo
Journal of natural products 62 (12), 1700-1701, 1999
821999
Patterns and reasons for kratom (Mitragyna speciosa) use among current and former opioid poly-drug users
D Singh, NJY Chear, S Narayanan, F Leon, A Sharma, CR McCurdy, ...
Journal of Ethnopharmacology 249, 112462, 2020
812020
Perspective on the Therapeutics of Anti-Snake Venom
I Gómez-Betancur, V Gogineni, A Salazar-Ospina, F León
Molecules 24 (18), 3276, 2019
762019
Inhibition of human monoamine oxidase A and B by flavonoids isolated from two Algerian medicinal plants
F Larit, KM Elokely, ND Chaurasiya, S Benyahia, MA Nael, F León, ...
Phytomedicine 40, 27-36, 2018
712018
A flavonoid with cytotoxic activity and other constituents from Centaurea africana
R Seghiri, O Boumaza, R Mekkiou, S Benayache, P Mosset, J Quintana, ...
Phytochemistry Letters 2 (3), 114-118, 2009
712009
Phenolic Compounds of Dragon's Blood from Dracaena d raco
AG González, F León, L Sánchez-Pinto, JI Padrón, J Bermejo
Journal of natural products 63 (9), 1297-1299, 2000
692000
Pharmacological Comparison of Mitragynine and 7-Hydroxymitragynine: In Vitro Affinity and Efficacy for Mu-Opioid Receptor and Opioid-Like Behavioral Effects in Rats
Journal of Pharmacology and Experimental Therapeutics 376 (3), 410-427, 2021
682021
Icogenin, a new cytotoxic steroidal saponin isolated from Dracaena draco
JC Hernandez, F León, J Quintana, F Estévez, J Bermejo
Bioorganic & medicinal chemistry 12 (16), 4423-4429, 2004
682004
Novel cytostatic lanostanoid triterpenes from Ganoderma australe
F Leon, M Valencia, A Rivera, I Nieto, J Quintana, F Estevez, J Bermejo
Helvetica chimica acta 86 (9), 3088-3095, 2003
632003
Synthesis and antiproliferative activity of a new compound containing an α-methylene-γ-lactone group
AG González, MH Silva, JI Padrón, F León, E Reyes, M Álvarez-Mon, ...
Journal of medicinal chemistry 45 (12), 2358-2361, 2002
612002
Motives for using Kratom (Mitragyna speciosa Korth.) among regular users in Malaysia
D Singh, S Narayanan, CP Müller, MT Swogger, NJY Chear, EB Dzulkapli, ...
Journal of ethnopharmacology 233, 34-40, 2019
602019
Antimicrobial and antiprotozoal activities of secondary metabolites from the fungus Eurotium repens
J Gao, MM Radwan, F León, X Wang, MR Jacob, BL Tekwani, SI Khan, ...
Medicinal Chemistry Research 21, 3080-3086, 2012
602012
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