Follow
E.D. Michelakis
Title
Cited by
Cited by
Year
A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth
S Bonnet, SL Archer, J Allalunis-Turner, A Haromy, C Beaulieu, ...
Cancer cell 11 (1), 37-51, 2007
19212007
Metabolic modulation of glioblastoma with dichloroacetate
ED Michelakis, G Sutendra, P Dromparis, L Webster, A Haromy, E Niven, ...
Science translational medicine 2 (31), 31ra34-31ra34, 2010
8752010
Dichloroacetate (DCA) as a potential metabolic-targeting therapy for cancer
ED Michelakis, L Webster, JR Mackey
British journal of cancer 99 (7), 989-994, 2008
8532008
Inflammation, growth factors, and pulmonary vascular remodeling
PM Hassoun, L Mouthon, JA Barberà, S Eddahibi, SC Flores, ...
Journal of the american college of cardiology 54 (1_Supplement_S), S10-S19, 2009
8292009
Oral sildenafil is an effective and specific pulmonary vasodilator in patients with pulmonary arterial hypertension: comparison with inhaled nitric oxide
E Michelakis, W Tymchak, D Lien, L Webster, K Hashimoto, S Archer
Circulation 105 (20), 2398-2403, 2002
7782002
An abnormal mitochondrial–hypoxia inducible factor-1α–Kv channel pathway disrupts oxygen sensing and triggers pulmonary arterial hypertension in fawn hooded rats: similarities …
S Bonnet, ED Michelakis, CJ Porter, MA Andrade-Navarro, B Thébaud, ...
Circulation 113 (22), 2630-2641, 2006
6612006
Relevant issues in the pathology and pathobiology of pulmonary hypertension
RM Tuder, SL Archer, P Dorfmüller, SC Erzurum, C Guignabert, ...
Journal of the American College of Cardiology 62 (25S), D4-D12, 2013
6422013
Phosphodiesterase type 5 is highly expressed in the hypertrophied human right ventricle, and acute inhibition of phosphodiesterase type 5 improves contractility
J Nagendran, SL Archer, D Soliman, V Gurtu, R Moudgil, A Haromy, ...
Circulation 116 (3), 238-248, 2007
6002007
Hypoxic pulmonary vasoconstriction
R Moudgil, ED Michelakis, SL Archer
Journal of applied physiology 98 (1), 390-403, 2005
5992005
Vascular endothelial growth factor gene therapy increases survival, promotes lung angiogenesis, and prevents alveolar damage in hyperoxia-induced lung injury: evidence that …
B Thébaud, F Ladha, ED Michelakis, M Sawicka, G Thurston, F Eaton, ...
Circulation 112 (16), 2477-2486, 2005
5662005
Comprehensive invasive and noninvasive approach to the right ventricle–pulmonary circulation unit: state of the art and clinical and research implications
HC Champion, ED Michelakis, PM Hassoun
Circulation 120 (11), 992-1007, 2009
5652009
Dichloroacetate prevents and reverses pulmonary hypertension by inducing pulmonary artery smooth muscle cell apoptosis
MS McMurtry, S Bonnet, X Wu, JRB Dyck, A Haromy, K Hashimoto, ...
Circulation research 95 (8), 830-840, 2004
5542004
A nuclear pyruvate dehydrogenase complex is important for the generation of acetyl-CoA and histone acetylation
G Sutendra, A Kinnaird, P Dromparis, R Paulin, TH Stenson, A Haromy, ...
Cell 158 (1), 84-97, 2014
5342014
Long-term treatment with oral sildenafil is safe and improves functional capacity and hemodynamics in patients with pulmonary arterial hypertension
ED Michelakis, W Tymchak, M Noga, L Webster, XC Wu, D Lien, ...
Circulation 108 (17), 2066-2069, 2003
5162003
Gene therapy targeting survivin selectively induces pulmonary vascular apoptosis and reverses pulmonary arterial hypertension
MS McMurtry, SL Archer, DC Altieri, S Bonnet, A Haromy, G Harry, ...
The Journal of clinical investigation 115 (6), 1479-1491, 2005
4682005
Dichloroacetate, a metabolic modulator, prevents and reverses chronic hypoxic pulmonary hypertension in rats: role of increased expression and activity of voltage-gated …
ED Michelakis, MS McMurtry, XC Wu, JRB Dyck, R Moudgil, TA Hopkins, ...
Circulation 105 (2), 244-250, 2002
4512002
The nuclear factor of activated T cells in pulmonary arterial hypertension can be therapeutically targeted
S Bonnet, G Rochefort, G Sutendra, SL Archer, A Haromy, L Webster, ...
Proceedings of the National Academy of Sciences 104 (27), 11418-11423, 2007
4382007
Differential distribution of electrophysiologically distinct myocytes in conduit and resistance arteries determines their response to nitric oxide and hypoxia
SL Archer, JMC Huang, HL Reeve, V Hampl, S Tolarová, E Michelakis, ...
Circulation research 78 (3), 431-442, 1996
4231996
Metabolic control of epigenetics in cancer
A Kinnaird, S Zhao, KE Wellen, ED Michelakis
Nature Reviews Cancer 16 (11), 694-707, 2016
3942016
Diversity in mitochondrial function explains differences in vascular oxygen sensing
ED Michelakis, V Hampl, A Nsair, XC Wu, G Harry, A Haromy, R Gurtu, ...
Circulation research 90 (12), 1307-1315, 2002
3792002
The system can't perform the operation now. Try again later.
Articles 1–20