p53 inhibits CRISPR–Cas9 engineering in human pluripotent stem cells RJ Ihry, KA Worringer, MR Salick, E Frias, D Ho, K Theriault, S Kommineni, ... Nature medicine 24 (7), 939-946, 2018 | 936 | 2018 |
YAP, but not RSPO-LGR4/5, signaling in biliary epithelial cells promotes a ductular reaction in response to liver injury L Planas-Paz, T Sun, M Pikiolek, NR Cochran, S Bergling, V Orsini, ... Cell Stem Cell 25 (1), 39-53. e10, 2019 | 174 | 2019 |
TMEM 41B is a novel regulator of autophagy and lipid mobilization F Moretti, P Bergman, S Dodgson, D Marcellin, I Claerr, JM Goodwin, ... EMBO reports 19 (9), e45889, 2018 | 138 | 2018 |
Diverse repertoire of human adipocyte subtypes develops from transcriptionally distinct mesenchymal progenitor cells SY Min, A Desai, Z Yang, A Sharma, T DeSouza, RMJ Genga, ... Proceedings of the National Academy of Sciences 116 (36), 17970-17979, 2019 | 118 | 2019 |
Gene expression analysis in pregnant women and their infants identifies unique fetal biomarkers that circulate in maternal blood JL Maron, KL Johnson, D Slonim, CQ Lai, M Ramoni, G Alterovitz, ... The Journal of clinical investigation 117 (10), 3007-3019, 2007 | 95 | 2007 |
USP7 inhibits Wnt/β-catenin signaling through promoting stabilization of Axin L Ji, B Lu, R Zamponi, O Charlat, R Aversa, Z Yang, F Sigoillot, X Zhu, ... Nature Communications 10 (1), 4184, 2019 | 93 | 2019 |
Tankyrase Inhibitor Sensitizes Lung Cancer Cells to Endothelial Growth Factor Receptor (EGFR) Inhibition via Stabilizing Angiomotins and Inhibiting YAP Signaling H Wang, B Lu, J Castillo, Y Zhang, Z Yang, G McAllister, A Lindeman, ... Journal of Biological Chemistry 291 (29), 15256-15266, 2016 | 75 | 2016 |
Human thermogenic adipocyte regulation by the long noncoding RNA LINC00473 KV Tran, EL Brown, T DeSouza, NZ Jespersen, C Nandrup-Bus, Q Yang, ... Nature Metabolism 2 (5), 397-412, 2020 | 74 | 2020 |
Genome-Scale CRISPR Screens Identify Human Pluripotency-Specific Genes RJ Ihry, MR Salick, DJ Ho, M Sondey, S Kommineni, S Paula, J Raymond, ... Cell Reports 27 (2), 616-630. e6, 2019 | 73 | 2019 |
mTORC1 signaling suppresses Wnt/β-catenin signaling through DVL-dependent regulation of Wnt receptor FZD level H Zeng, B Lu, R Zamponi, Z Yang, K Wetzel, J Loureiro, S Mohammadi, ... Proceedings of the National Academy of Sciences 115 (44), E10362-E10369, 2018 | 63 | 2018 |
A hospital-based study on the use of alternative medicine in patients with chronic liver and gastrointestinal diseases ZC Yang, SH Yang, SS Yang, DS Chen The American journal of Chinese medicine 30 (04), 637-643, 2002 | 58 | 2002 |
P53 toxicity is a hurdle to CRISPR/CAS9 screening and engineering in human pluripotent stem cells RJ Ihry, KA Worringer, MR Salick, E Frias, D Ho, K Theriault, S Kommineni, ... bioRxiv, 168443, 2017 | 56 | 2017 |
Bile acid analogues are activators of pyrin inflammasome I Alimov, S Menon, N Cochran, R Maher, Q Wang, J Alford, JB Concannon, ... Journal of Biological Chemistry 294 (10), 3359-3366, 2019 | 46 | 2019 |
Angiogenesis in adipose tissue and obesity S Corvera, J Solivan-Rivera, Z Yang Loureiro Angiogenesis 25 (4), 439-453, 2022 | 38 | 2022 |
Genome-wide CRISPR screening reveals genetic modifiers of mutant EGFR dependence in human NSCLC H Zeng, J Castillo-Cabrera, M Manser, B Lu, Z Yang, V Strande, D Begue, ... eLife 8, e50223, 2019 | 38 | 2019 |
Identification of a novel NAMPT inhibitor by CRISPR/Cas9 chemogenomic profiling in mammalian cells D Estoppey, JW Hewett, CT Guy, E Harrington, JR Thomas, M Schirle, ... Scientific reports 7 (1), 42728, 2017 | 37 | 2017 |
Identification of ICAT as an APC Inhibitor, Revealing Wnt-Dependent Inhibition of APC-Axin Interaction L Ji, B Lu, Z Wang, Z Yang, J Reece-Hoyes, C Russ, W Xu, F Cong Molecular cell 72 (1), 37-47. e4, 2018 | 31 | 2018 |
Adipocyte heterogeneity underlying adipose tissue functions Z Yang Loureiro, J Solivan-Rivera, S Corvera Endocrinology 163 (1), bqab138, 2022 | 20 | 2022 |
TRRAP is a central regulator of human multiciliated cell formation Z Wang, LW Plasschaert, S Aryal, NA Renaud, Z Yang, R Choo-Wing, ... Journal of Cell Biology 217 (6), 1941-1955, 2018 | 16 | 2018 |
Cell adhesion molecule KIRREL1 is a feedback regulator of Hippo signaling recruiting SAV1 to cell-cell contact sites A Paul, S Annunziato, B Lu, T Sun, O Evrova, L Planas-Paz, V Orsini, ... Nature Communications 13 (1), 1-14, 2022 | 15 | 2022 |