A PET imaging agent for evaluating PARP-1 expression in ovarian cancer M Makvandi, A Pantel, L Schwartz, E Schubert, K Xu, CJ Hsieh, C Hou, ... The Journal of clinical investigation 128 (5), 2116-2126, 2018 | 119 | 2018 |
Sigma-2 Receptor/TMEM97 and PGRMC-1 Increase the Rate of Internalization of LDL by LDL Receptor through the Formation of a Ternary Complex A Riad, C Zeng, CC Weng, H Winters, K Xu, M Makvandi, T Metz, S Carlin, ... Scientific reports 8 (1), 16845, 2018 | 113 | 2018 |
Bacterial infection imaging with [18F] fluoropropyl-trimethoprim MA Sellmyer, I Lee, C Hou, CC Weng, S Li, BP Lieberman, C Zeng, ... Proceedings of the National Academy of Sciences 114 (31), 8372-8377, 2017 | 97 | 2017 |
Imaging CAR T cell trafficking with eDHFR as a PET reporter gene MA Sellmyer, SA Richman, K Lohith, C Hou, CC Weng, RH Mach, ... Molecular Therapy 28 (1), 42-51, 2020 | 81 | 2020 |
Development of a positron emission tomography radiotracer for imaging elevated levels of superoxide in neuroinflammation C Hou, CJ Hsieh, S Li, H Lee, TJ Graham, K Xu, CC Weng, RK Doot, ... ACS chemical neuroscience 9 (3), 578-586, 2017 | 66 | 2017 |
GMP-compliant automated synthesis of [18F] AV-45 (Florbetapir F 18) for imaging β-amyloid plaques in human brain CH Yao, KJ Lin, CC Weng, T Hsiao, YS Ting, TC Yen, TR Jan, ... Applied Radiation and Isotopes 68 (12), 2293-2297, 2010 | 61 | 2010 |
The sigma-2 receptor/TMEM97, PGRMC1, and LDL receptor complex are responsible for the cellular uptake of Aβ42 and its protein aggregates A Riad, Z Lengyel-Zhand, C Zeng, CC Weng, VMY Lee, JQ Trojanowski, ... Molecular neurobiology 57, 3803-3813, 2020 | 57 | 2020 |
TMEM97 and PGRMC1 do not mediate sigma-2 ligand-induced cell death C Zeng, CC Weng, ME Schneider Jr, L Puentes, A Riad, K Xu, ... Cell death discovery 5 (1), 58, 2019 | 54 | 2019 |
Targeting PARP-1 with alpha-particles is potently cytotoxic to human neuroblastoma in preclinical models M Makvandi, H Lee, LN Puentes, SW Reilly, KS Rathi, CC Weng, ... Molecular cancer therapeutics 18 (7), 1195-1204, 2019 | 47 | 2019 |
Examination of diazaspiro cores as piperazine bioisosteres in the olaparib framework shows reduced DNA damage and cytotoxicity SW Reilly, LN Puentes, K Wilson, CJ Hsieh, CC Weng, M Makvandi, ... Journal of medicinal chemistry 61 (12), 5367-5379, 2018 | 41 | 2018 |
Identification of a nanomolar affinity α-synuclein fibril imaging probe by ultra-high throughput in silico screening JJ Ferrie, Z Lengyel-Zhand, B Janssen, MG Lougee, S Giannakoulias, ... Chemical Science 11 (47), 12746-12754, 2020 | 32 | 2020 |
Cell-proliferation imaging for monitoring response to CDK4/6 inhibition combined with endocrine-therapy in breast cancer: comparison of [18F] FLT and [18F] ISO-1 PET/CT A Elmi, M Makvandi, CC Weng, C Hou, AS Clark, RH Mach, DA Mankoff Clinical Cancer Research 25 (10), 3063-3073, 2019 | 31 | 2019 |
Highly Selective Dopamine D3 Receptor Antagonists with Arylated Diazaspiro Alkane Cores SW Reilly, S Griffin, M Taylor, K Sahlholm, CC Weng, K Xu, DA Jacome, ... Journal of medicinal chemistry 60 (23), 9905-9910, 2017 | 31 | 2017 |
Characterization of 18F-PM-PBB3 (18F-APN-1607) Uptake in the rTg4510 Mouse Model of Tauopathy CC Weng, IT Hsiao, QF Yang, CH Yao, CY Tai, MF Wu, TC Yen, MK Jang, ... Molecules 25 (7), 1750, 2020 | 29 | 2020 |
Amyloid plaque imaging from IMPY/SPECT to AV-45/PET KJ Lin, T Hsiao, TC Yen, SP Wey Chang Gung Med J 35, 211-8, 2012 | 24 | 2012 |
Quantitative analysis of the therapeutic effect of magnolol on MPTP-induced mouse model of Parkinson’s disease using in vivo 18F-9-fluoropropyl-(+ … CC Weng, ZA Chen, KT Chao, TW Ee, KJ Lin, MH Chan, IT Hsiao, TC Yen, ... PLoS One 12 (3), e0173503, 2017 | 22 | 2017 |
Synthesis and evaluation of an AZD2461 [18F] PET probe in non-human primates reveals the PARP-1 inhibitor to be non-blood-brain barrier penetrant SW Reilly, LN Puentes, A Schmitz, CJ Hsieh, CC Weng, C Hou, S Li, ... Bioorganic chemistry 83, 242-249, 2019 | 20 | 2019 |
Leveraging a Low-Affinity Diazaspiro Orthosteric Fragment to Reduce Dopamine D3 Receptor (D3R) Ligand Promiscuity across Highly Conserved Aminergic G … SW Reilly, AA Riad, CJ Hsieh, K Sahlholm, DA Jacome, S Griffin, M Taylor, ... Journal of Medicinal Chemistry 62 (10), 5132-5147, 2019 | 18 | 2019 |
Validation of an 18F-labeled biphenylalkyne as a positron emission tomography imaging agent for β-amyloid plaques SP Wey, CC Weng, KJ Lin, CH Yao, TC Yen, HF Kung, D Skovronsky, ... Nuclear medicine and biology 36 (4), 411-417, 2009 | 18 | 2009 |
[18F]FP-(+)-DTBZ PET study in a lactacystin-treated rat model of Parkinson disease CC Weng, SL Huang, ZA Chen, KJ Lin, IT Hsiao, TC Yen, MP Kung, ... Annals of Nuclear Medicine 31, 506-513, 2017 | 14 | 2017 |