Следене
Gavin Williams
Заглавие
Позовавания
Позовавания
Година
Expanding the promiscuity of a natural-product glycosyltransferase by directed evolution
GJ Williams, C Zhang, JS Thorson
Nature chemical biology 3 (10), 657-662, 2007
3102007
Probing the aglycon promiscuity of an engineered glycosyltransferase
RW Gantt, RD Goff, GJ Williams, JS Thorson
Angewandte Chemie (International ed. in English) 47 (46), 8889, 2008
1562008
Modifying the stereochemistry of an enzyme-catalyzed reaction by directed evolution
GJ Williams, S Domann, A Nelson, A Berry
Proceedings of the National Academy of Sciences 100 (6), 3143-3148, 2003
1482003
Optimizing glycosyltransferase specificity via “hot spot” saturation mutagenesis presents a catalyst for novobiocin glycorandomization
GJ Williams, RD Goff, C Zhang, JS Thorson
Chemistry & biology 15 (4), 393-401, 2008
1172008
The impact of enzyme engineering upon natural product glycodiversification
GJ Williams, RW Gantt, JS Thorson
Current opinion in chemical biology 12 (5), 556-564, 2008
1142008
Directed evolution of enzymes for biocatalysis and the life sciences
GJ Williams, AS Nelson, A Berry
Cellular and molecular life sciences CMLS 61, 3034-3046, 2004
1102004
Engineering polyketide synthases and nonribosomal peptide synthetases
GJ Williams
Current opinion in structural biology 23 (4), 603-612, 2013
1092013
Development of transcription factor-based designer macrolide biosensors for metabolic engineering and synthetic biology
CM Kasey, M Zerrad, Y Li, TA Cropp, GJ Williams
ACS synthetic biology 7 (1), 227-239, 2018
1022018
Poly Specific trans-Acyltransferase Machinery Revealed via Engineered Acyl-CoA Synthetases
I Koryakina, J McArthur, S Randall, MM Draelos, EM Musiol, ...
ACS chemical biology 8 (1), 200-208, 2013
942013
Natural product glycosyltransferases: properties and applications
GJ Williams, JS Thorson
Advances in Enzymology & Related Areas of Molecular Biology 76, 55, 2009
812009
Creation of a pair of stereochemically complementary biocatalysts
GJ Williams, T Woodhall, LM Farnsworth, A Nelson, A Berry
Journal of the American Chemical Society 128 (50), 16238-16247, 2006
802006
Inversion of extender unit selectivity in the erythromycin polyketide synthase by acyltransferase domain engineering
I Koryakina, C Kasey, JB McArthur, AN Lowell, JA Chemler, S Li, ...
ACS chemical biology 12 (1), 114-123, 2017
772017
Recombinant E. coli Prototype Strains for in Vivo Glycorandomization
GJ Williams, J Yang, C Zhang, JS Thorson
ACS chemical biology 6 (1), 95-100, 2011
762011
An artificial pathway for isoprenoid biosynthesis decoupled from native hemiterpene metabolism
S Lund, R Hall, GJ Williams
ACS synthetic biology 8 (2), 232-238, 2019
752019
Promiscuity of a modular polyketide synthase towards natural and non-natural extender units
I Koryakina, JB McArthur, MM Draelos, GJ Williams
Organic & biomolecular chemistry 11 (27), 4449-4458, 2013
732013
Mutant malonyl‐CoA synthetases with altered specificity for polyketide synthase extender unit generation
I Koryakina, GJ Williams
ChemBioChem 12 (15), 2289-2293, 2011
722011
Transcription factor-based biosensors: a molecular-guided approach for natural product engineering
MM Mitchler, JM Garcia, NE Montero, GJ Williams
Current opinion in biotechnology 69, 172-181, 2021
612021
A high-throughput fluorescence-based glycosyltransferase screen and its application in directed evolution
GJ Williams, JS Thorson
Nature Protocols 3 (3), 357-362, 2008
612008
Creation of a tailored aldolase for the parallel synthesis of sialic acid mimetics
T Woodhall, G Williams, A Berry, A Nelson
Angewandte Chemie 117 (14), 2147-2150, 2005
582005
Polyketide bioderivatization using the promiscuous acyltransferase KirCII
EM Musiol-Kroll, F Zubeil, T Schafhauser, T Härtner, A Kulik, J McArthur, ...
ACS synthetic biology 6 (3), 421-427, 2017
572017
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