Следене
Qian Chen
Qian Chen
Professor of Medical Science, Alpert Medical School of Brown University
Потвърден имейл адрес: brown.edu
Заглавие
Позовавания
Позовавания
Година
Osteopontin gene regulation by oscillatory fluid flow via intracellular calcium mobilization and activation of mitogen-activated protein kinase in MC3T3–E1 osteoblasts
J You, GC Reilly, X Zhen, CE Yellowley, Q Chen, HJ Donahue, ...
Journal of Biological Chemistry 276 (16), 13365-13371, 2001
5002001
Substrate deformation levels associated with routine physical activity are less stimulatory to bone cells relative to loading-induced oscillatory fluid flow
J You, CE Yellowley, HJ Donahue, Y Zhang, Q Chen, CR Jacobs
J. Biomech. Eng. 122 (4), 387-393, 2000
4422000
The role of osteopontin in the progression of solid organ tumour
H Zhao, Q Chen, A Alam, J Cui, KC Suen, AP Soo, S Eguchi, J Gu, D Ma
Cell death & disease 9 (3), 1-15, 2018
2922018
Stimulation of matrix metalloprotease 3 release from human chondrocytes by the interaction of stromal cell‐derived factor 1 and CXC chemokine receptor 4
K Kanbe, K Takagishi, Q Chen
Arthritis & Rheumatism 46 (1), 130-137, 2002
2582002
Mechanoregulation of chondrocyte proliferation, maturation, and hypertrophy: ion-channel dependent transduction of matrix deformation signals
Q Wu, Q Chen
Experimental cell research 256 (2), 383-391, 2000
2522000
Ptpn11 deletion in a novel progenitor causes metachondromatosis by inducing hedgehog signalling
W Yang, J Wang, DC Moore, H Liang, M Dooner, Q Wu, R Terek, Q Chen, ...
Nature 499 (7459), 491-495, 2013
2452013
Indian hedgehog is an essential component of mechanotransduction complex to stimulate chondrocyte proliferation
Q Wu, Y Zhang, Q Chen
Journal of Biological Chemistry 276 (38), 35290-35296, 2001
2372001
Osteocytes subjected to pulsating fluid flow regulate osteoblast proliferation and differentiation
PS Vezeridis, CM Semeins, Q Chen, J Klein-Nulend
Biochemical and biophysical research communications 348 (3), 1082-1088, 2006
2202006
miR-146a, an IL-1β responsive miRNA, induces vascular endothelial growth factor and chondrocyte apoptosis by targeting Smad4
J Li, J Huang, L Dai, D Yu, Q Chen, X Zhang, K Dai
Arthritis research & therapy 14, 1-13, 2012
2062012
Activation of Indian hedgehog promotes chondrocyte hypertrophy and upregulation of MMP-13 in human osteoarthritic cartilage
F Wei, J Zhou, X Wei, J Zhang, BC Fleming, R Terek, M Pei, Q Chen, T Liu, ...
Osteoarthritis and cartilage 20 (7), 755-763, 2012
1772012
Collagen types IX and X in the developing chick tibiotarsus: analyses of mRNAs and proteins
TF Linsenmayer, Q Chen, E Gibney, MK Gordon, JK Marchant, R Mayne, ...
Development 111 (1), 191-196, 1991
1691991
MiR-365: a mechanosensitive microRNA stimulates chondrocyte differentiation through targeting histone deacetylase 4
YJ Guan, X Yang, L Wei, Q Chen
The FASEB Journal 25 (12), 4457, 2011
1682011
Defective autophagy in osteoblasts induces endoplasmic reticulum stress and causes remarkable bone loss
H Li, D Li, Z Ma, Z Qian, X Kang, X Jin, F Li, X Wang, Q Chen, H Sun, ...
Autophagy 14 (10), 1726-1741, 2018
1612018
Synovectomy reduces stromal-cell-derived factor-1 (SDF-1) which is involved in the destruction of cartilage in osteoarthritis and rheumatoid arthritis
K Kanbe, T Takemura, K Takeuchi, Q Chen, K Takagishi, K Inoue
The Journal of Bone & Joint Surgery British Volume 86 (2), 296-300, 2004
1462004
Progression and recapitulation of the chondrocyte differentiation program: cartilage matrix protein is a marker for cartilage maturation
Q Chen, DM Johnson, DR Haudenschild, PF Goetinck
Developmental biology 172 (1), 293-306, 1995
1431995
Adipokines: new therapeutic target for osteoarthritis?
C Xie, Q Chen
Current rheumatology reports 21, 1-9, 2019
1412019
Mitogen-activated protein kinase p38 mediates regulation of chondrocyte differentiation by parathyroid hormone
X Zhen, L Wei, Q Wu, Y Zhang, Q Chen
Journal of Biological Chemistry 276 (7), 4879-4885, 2001
1352001
Functional knockout of the matrilin-3 gene causes premature chondrocyte maturation to hypertrophy and increases bone mineral density and osteoarthritis
L van der Weyden, L Wei, J Luo, X Yang, DE Birk, DJ Adams, A Bradley, ...
The American journal of pathology 169 (2), 515-527, 2006
1252006
CXCR4/SDF1 mediate hypoxia induced chondrosarcoma cell invasion through ERK signaling and increased MMP1 expression
X Sun, L Wei, Q Chen, RM Terek
Molecular Cancer 9, 1-11, 2010
1132010
Disrupting the Indian hedgehog signaling pathway in vivo attenuates surgically induced osteoarthritis progression in Col2a1-CreER T2; Ihh fl/fl mice
J Zhou, Q Chen, B Lanske, BC Fleming, R Terek, X Wei, G Zhang, ...
Arthritis research & therapy 16, 1-10, 2014
1122014
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Статии 1–20