| Biallelic Deleterious BRCA1 Mutations in a Woman with Early-Onset Ovarian Cancer SM Domchek, J Tang, J Stopfer, DR Lilli, N Hamel, M Tischkowitz, ... Cancer discovery 3 (4), 399-405, 2013 | 180 | 2013 |
| MERIT40 controls BRCA1–Rap80 complex integrity and recruitment to DNA double-strand breaks G Shao, J Patterson-Fortin, TE Messick, D Feng, N Shanbhag, Y Wang, ... Genes & development 23 (6), 740-754, 2009 | 175 | 2009 |
| The ubiquitin landscape at DNA double-strand breaks TE Messick, RA Greenberg Journal of Cell Biology 187 (3), 319-326, 2009 | 149 | 2009 |
| Structural basis for ubiquitin recognition by the Otu1 ovarian tumor domain protein TE Messick, NS Russell, AJ Iwata, KL Sarachan, R Shiekhattar, ... Journal of Biological Chemistry 283 (16), 11038-11049, 2008 | 139 | 2008 |
| Structure-based design of small-molecule inhibitors of EBNA1 DNA binding blocks Epstein-Barr virus latent infection and tumor growth TE Messick, GR Smith, SS Soldan, ME McDonnell, JS Deakyne, ... Science translational medicine 11 (482), eaau5612, 2019 | 99 | 2019 |
| Differential regulation of JAMM domain deubiquitinating enzyme activity within the RAP80 complex J Patterson-Fortin, G Shao, H Bretscher, TE Messick, RA Greenberg Journal of Biological Chemistry 285 (40), 30971-30981, 2010 | 98 | 2010 |
| Crystal structure and functional interpretation of the erythrocyte spectrin tetramerization domain complex JJ Ipsaro, SL Harper, TE Messick, R Marmorstein, A Mondragón, ... Blood, The Journal of the American Society of Hematology 115 (23), 4843-4852, 2010 | 85 | 2010 |
| Familial breast cancer screening reveals an alteration in the RAP80 UIM domain that impairs DNA damage response function J Nikkilä, KA Coleman, D Morrissey, K Pylkäs, H Erkko, TE Messick, ... Oncogene 28 (16), 1843-1852, 2009 | 80 | 2009 |
| Carcinoma-risk variant of EBNA1 deregulates Epstein-Barr virus episomal latency J Dheekollu, K Malecka, A Wiedmer, HJ Delecluse, AKS Chiang, ... Oncotarget 8 (5), 7248, 2017 | 58 | 2017 |
| Development of a high-throughput screen for inhibitors of Epstein-Barr virus EBNA1 S Thompson, T Messick, DC Schultz, M Reichman, PM Lieberman Journal of biomolecular screening 15 (9), 1107-1115, 2010 | 57 | 2010 |
| Noncysteinyl Coordination to the [4Fe-4S]2+ Cluster of the DNA Repair Adenine Glycosylase MutY Introduced via Site-Directed Mutagenesis. Structural Characterization of an … TE Messick, NH Chmiel, MP Golinelli, MR Langer, L Joshua-Tor, ... Biochemistry 41 (12), 3931-3942, 2002 | 54 | 2002 |
| Computational analysis of EBNA1 “druggability” suggests novel insights for Epstein-Barr virus inhibitor design E Gianti, TE Messick, PM Lieberman, RJ Zauhar Journal of computer-aided molecular design 30, 285-303, 2016 | 44 | 2016 |
| The natural stilbenoid (–)-hopeaphenol inhibits cellular entry of SARS-CoV-2 USA-WA1/2020, B. 1.1. 7, and B. 1.351 variants I Tietjen, J Cassel, ET Register, XY Zhou, TE Messick, F Keeney, LD Lu, ... Antimicrobial Agents and Chemotherapy 65 (12), 10.1128/aac. 00772-21, 2021 | 40 | 2021 |
| Internal eliminated sequences interrupting the Oxytricha 81 locus: allelic divergence, conservation, conversions, and possible transposon origins. A Seegmiller, KR Williams, RL Hammersmith, TG Doak, D Witherspoon, ... Molecular biology and evolution 13 (10), 1351-1362, 1996 | 38 | 1996 |
| Inhibition of pro-HGF activation by SRI31215, a novel approach to block oncogenic HGF/MET signaling BY Owusu, N Bansal, PKM Venukadasula, LJ Ross, TE Messick, S Goel, ... Oncotarget 7 (20), 29492, 2016 | 35 | 2016 |
| Cell-cycle-dependent EBNA1-DNA crosslinking promotes replication termination at oriP and viral episome maintenance J Dheekollu, A Wiedmer, K Ayyanathan, JS Deakyne, TE Messick, ... Cell 184 (3), 643-654. e13, 2021 | 31 | 2021 |
| Epigenetic plasticity enables CNS-trafficking of EBV-infected B lymphocytes SS Soldan, C Su, RJ Lamontagne, N Grams, F Lu, Y Zhang, JD Gesualdi, ... PLoS Pathogens 17 (6), e1009618, 2021 | 27 | 2021 |
| Structural and functional basis for an EBNA1 hexameric ring in Epstein-Barr virus episome maintenance JS Deakyne, KA Malecka, TE Messick, PM Lieberman Journal of Virology 91 (19), 10.1128/jvi. 01046-17, 2017 | 27 | 2017 |
| EBNA1 inhibitors have potent and selective antitumor activity in xenograft models of Epstein–Barr virus-associated gastric cancer SS Soldan, EM Anderson, DM Frase, Y Zhang, LB Caruso, Y Wang, ... Gastric Cancer 24 (5), 1076-1088, 2021 | 25 | 2021 |
| Design and synthesis of nonpeptide inhibitors of hepatocyte growth factor activation PKM Venukadasula, BY Owusu, N Bansal, LJ Ross, JV Hobrath, D Bao, ... ACS medicinal chemistry letters 7 (2), 177-181, 2016 | 25 | 2016 |
