Karsten A Pilones
Karsten A Pilones
Weill Cornell Medicine
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TGFβ is a master regulator of radiation therapy-induced antitumor immunity
C Vanpouille-Box, JM Diamond, KA Pilones, J Zavadil, JS Babb, ...
Cancer research 75 (11), 2232-2242, 2015
TGFβ1 Inhibition Increases the Radiosensitivity of Breast Cancer Cells In Vitro and Promotes Tumor Control by Radiation In VivoRadiosensitization by TGFβ Inhibitors
F Bouquet, A Pal, KA Pilones, S Demaria, B Hann, RJ Akhurst, JS Babb, ...
Clinical Cancer Research 17 (21), 6754-6765, 2011
Exosomes Shuttle TREX1-Sensitive IFN-Stimulatory dsDNA from Irradiated Cancer Cells to DCsRT Confers the Immunogenicity of Tumor-Derived Exosomes
JM Diamond, C Vanpouille-Box, S Spada, NP Rudqvist, JR Chapman, ...
Cancer immunology research 6 (8), 910-920, 2018
Suppressing T cell motility induced by anti–CTLA-4 monotherapy improves antitumor effects
MG Ruocco, KA Pilones, N Kawashima, M Cammer, J Huang, JS Babb, ...
The Journal of clinical investigation 122 (10), 3718-3730, 2012
Radiotherapy and CTLA-4 Blockade Shape the TCR Repertoire of Tumor-Infiltrating T CellsTCR Repertoire Shaped by Radiation and CTLA-4 Blockade
NP Rudqvist, KA Pilones, C Lhuillier, E Wennerberg, JW Sidhom, ...
Cancer immunology research 6 (2), 139-150, 2018
Barriers to Radiation-Induced In Situ Tumor Vaccination
E Wennerberg, C Lhuillier, C Vanpouille-Box, KA Pilones, ...
Frontiers in Immunology 8, 229, 2017
In situ vaccination by radiotherapy to improve responses to anti-CTLA-4 treatment
C Vanpouille-Box, KA Pilones, E Wennerberg, SC Formenti, S Demaria
Vaccine 33 (51), 7415-7422, 2015
Combination of radiotherapy and immune checkpoint inhibitors
KA Pilones, C Vanpouille-Box, S Demaria
Seminars in radiation oncology 25 (1), 28-33, 2015
Invariant natural killer T cells regulate breast cancer response to radiation and CTLA-4 blockade
KA Pilones, N Kawashima, AM Yang, JS Babb, SC Formenti, S Demaria
Clinical cancer research 15 (2), 597-606, 2009
The optimal partnership of radiation and immunotherapy: from preclinical studies to clinical translation
S Demaria, KA Pilones, C Vanpouille-Box, EB Golden, SC Formenti
Radiation research 182 (2), 170-181, 2014
Invariant NKT cells as novel targets for immunotherapy in solid tumors
KA Pilones, J Aryankalayil, S Demaria
Clinical and Developmental Immunology 2012, 2012
Invariant natural killer T cells regulate anti-tumor immunity by controlling the population of dendritic cells in tumor and draining lymph nodes
KA Pilones, J Aryankalayil, JS Babb, S Demaria
Journal for ImmunoTherapy of Cancer 2, 1-13, 2014
Exploiting the stress response to radiation to sensitize poorly immunogenic tumors to anti-CTLA-4 treatment
S Demaria, KA Pilones, SC Formenti, ML Dustin
Oncoimmunology 2 (3), e23127, 2013
Converging focal radiation and immunotherapy in a preclinical model of triple negative breast cancer: contribution of VISTA blockade
KA Pilones, M Hensler, C Daviaud, J Kraynak, J Fucikova, L Galluzzi, ...
Oncoimmunology 9 (1), 1830524, 2020
CD8+ T-cell immune evasion enables oncolytic virus immunotherapy
A Pourchet, SR Fuhrmann, KA Pilones, S Demaria, AB Frey, M Mulvey, ...
EBioMedicine 5, 59-67, 2016
Radiotherapy Cooperates with IL15 to Induce Antitumor Immune ResponsesRadiotherapy and IL15 Induce Antitumor Immune Responses
KA Pilones, M Charpentier, E Garcia-Martinez, C Daviaud, J Kraynak, ...
Cancer immunology research 8 (8), 1054-1063, 2020
Transforming growth factor b1 inhibition increases the radiosensitivity of breast cancer cells in vitro and promotes tumor control by radiation in vivo
SF Bouquet, A Pal, KA Pilones, S Demaria, B Hann, RJ Akhurst, JS Babb, ...
Clin Cancer Res 17 (21), 6754-65, 2011
Gestational exposure to mercury leads to persistent changes in T-cell phenotype and function in adult DBF1 mice
K Pilones, A Tatum, J Gavalchin
Journal of Immunotoxicology 6 (3), 161-170, 2009
Melanoma and immunotherapy bridge 2015
VGY Nanda, W Peng, P Hwu, MA Davies, G Ciliberto, L Fattore, ...
Journal of Translational Medicine 14 (1), 1-27, 2016
Prenatal HgCl2 Exposure Alters Fetal Cell Phenotypes
K Pilones, ZW Lai, J Gavalchin
Journal of Immunotoxicology 4 (4), 295-301, 2007
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