In vivo engineering of oncogenic chromosomal rearrangements with the CRISPR/Cas9 system D Maddalo, E Manchado, CP Concepcion, C Bonetti, JA Vidigal, YC Han, ... Nature 516 (7531), 423-427, 2014 | 712 | 2014 |
The biological functions of miRNAs: lessons from in vivo studies JA Vidigal, A Ventura Trends in cell biology 25 (3), 137-147, 2015 | 531 | 2015 |
Germline deletion of the miR-17∼ 92 cluster causes skeletal and growth defects in humans L de Pontual, E Yao, P Callier, L Faivre, V Drouin, S Cariou, ... Nature genetics 43 (10), 1026-1030, 2011 | 359 | 2011 |
GuideScan software for improved single and paired CRISPR guide RNA design AR Perez, Y Pritykin, JA Vidigal, S Chhangawala, L Zamparo, CS Leslie, ... Nature biotechnology 35 (4), 347-349, 2017 | 233 | 2017 |
Intact p53-dependent responses in miR-34–deficient mice CP Concepcion, YC Han, P Mu, C Bonetti, E Yao, A D'andrea, JA Vidigal, ... PLoS genetics 8 (7), e1002797, 2012 | 228 | 2012 |
Rapid and efficient one-step generation of paired gRNA CRISPR-Cas9 libraries JA Vidigal, A Ventura Nature communications 6 (1), 8083, 2015 | 169 | 2015 |
In vivo, Argonaute-bound microRNAs exist predominantly in a reservoir of low molecular weight complexes not associated with mRNA G La Rocca, SH Olejniczak, AJ González, D Briskin, JA Vidigal, ... Proceedings of the National Academy of Sciences 112 (3), 767-772, 2015 | 128 | 2015 |
An allelic series of miR-17∼ 92–mutant mice uncovers functional specialization and cooperation among members of a microRNA polycistron YC Han, JA Vidigal, P Mu, E Yao, I Singh, AJ González, CP Concepcion, ... Nature genetics 47 (7), 766-775, 2015 | 119 | 2015 |
In vivo knockdown of Brachyury results in skeletal defects and urorectal malformations resembling caudal regression syndrome T Pennimpede, J Proske, A König, JA Vidigal, M Morkel, JB Bramsen, ... Developmental biology 372 (1), 55-67, 2012 | 54 | 2012 |
Embryonic stem cell miRNAs and their roles in development and disease JA Vidigal, A Ventura Seminars in cancer biology 22 (5-6), 428-436, 2012 | 47 | 2012 |
An inducible RNA interference system for the functional dissection of mouse embryogenesis JA Vidigal, M Morkel, L Wittler, A Brouwer-Lehmitz, P Grote, K Macura, ... Nucleic acids research 38 (11), e122-e122, 2010 | 30 | 2010 |
Inducible and reversible inhibition of miRNA-mediated gene repression in vivo G La Rocca, B King, B Shui, X Li, M Zhang, KM Akat, P Ogrodowski, ... Elife 10, e70948, 2021 | 26 | 2021 |
AGO unchained: Canonical and non-canonical roles of Argonaute proteins in mammals L Sala, S Chandrasekhar, JA Vidigal Frontiers in bioscience (Landmark edition) 25, 1, 2020 | 17 | 2020 |
AGO2 silences mobile transposons in the nucleus of quiescent cells L Sala, M Kumar, M Prajapat, S Chandrasekhar, RL Cosby, G La Rocca, ... Nature Structural & Molecular Biology 30 (12), 1985-1995, 2023 | 8 | 2023 |
CSC software corrects off-target mediated gRNA depletion in CRISPR-Cas9 essentiality screens AR Perez, L Sala, RK Perez, JA Vidigal Nature Communications 12 (1), 6461, 2021 | 8* | 2021 |
A catalytic function for mammalian Argonautes JA Vidigal Nature Reviews Molecular Cell Biology, 1-1, 2024 | | 2024 |
AGO2 localizes to the nucleus in quiescence and represses transposon expression M Kumar, JA Vidigal NATURE STRUCTURAL & MOLECULAR BIOLOGY 30 (12), 1838-1839, 2023 | | 2023 |
Research briefing M Kumar, JA Vidigal | | |