Следене
Gurpanna Saggu
Gurpanna Saggu
Senior Scientist, Takeda
Потвърден имейл адрес: takeda.com
Заглавие
Позовавания
Позовавания
Година
Identification of a novel mode of complement activation on stimulated platelets mediated by properdin and C3 (H2O)
G Saggu, C Cortes, HN Emch, G Ramirez, RG Worth, VP Ferreira
The Journal of Immunology 190 (12), 6457-6467, 2013
972013
Local release of properdin in the cellular microenvironment: role in pattern recognition and amplification of the alternative pathway of complement
C Cortes, JA Ohtola, G Saggu, VP Ferreira
Frontiers in immunology 3, 412, 2013
932013
Protection from septic peritonitis by rapid neutrophil recruitment through omental high endothelial venules
K Buscher, H Wang, X Zhang, P Striewski, B Wirth, G Saggu, ...
Nature communications 7 (1), 10828, 2016
722016
Low-dose recombinant properdin provides substantial protection against Streptococcus pneumoniae and Neisseria meningitidis infection
YM Ali, A Hayat, BM Saeed, KS Haleem, S Alshamrani, HI Kenawy, ...
Proceedings of the National Academy of Sciences 111 (14), 5301-5306, 2014
562014
Cis interaction between sialylated FcγRIIA and the αI-domain of Mac-1 limits antibody-mediated neutrophil recruitment
G Saggu, K Okubo, Y Chen, R Vattepu, N Tsuboi, F Rosetti, X Cullere, ...
Nature communications 9 (1), 5058, 2018
502018
Neutrophil FcγRIIA promotes IgG-mediated glomerular neutrophil capture via Abl/Src kinases
H Nishi, K Furuhashi, X Cullere, G Saggu, MJ Miller, Y Chen, F Rosetti, ...
The Journal of clinical investigation 127 (10), 3810-3826, 2017
492017
Properdin-mediated C5a production enhances stable binding of platelets to granulocytes in human whole blood
AZ Blatt, G Saggu, KV Kulkarni, C Cortes, JM Thurman, D Ricklin, ...
The Journal of Immunology 196 (11), 4671-4680, 2016
342016
Increased lymphocyte activation and atherosclerosis in CD47-deficient mice
D Engelbertsen, A Autio, RAF Verwilligen, MAC Depuydt, G Newton, ...
Scientific Reports 9 (1), 10608, 2019
322019
PKC-δ activation in neutrophils promotes fungal clearance
X Li, X Cullere, H Nishi, G Saggu, E Durand, MK Mansour, JM Tam, ...
Journal of Leucocyte Biology 100 (3), 581-588, 2016
322016
ATF3 and CH25H regulate effector trogocytosis and anti-tumor activities of endogenous and immunotherapeutic cytotoxic T lymphocytes
Z Lu, N McBrearty, J Chen, VS Tomar, H Zhang, G De Rosa, A Tan, ...
Cell metabolism 34 (9), 1342-1358. e7, 2022
212022
Factor H C-terminal domains are critical for regulation of platelet/granulocyte aggregate formation
AZ Blatt, G Saggu, C Cortes, AP Herbert, D Kavanagh, D Ricklin, ...
Frontiers in immunology 8, 305027, 2017
202017
Protection of regulatory T cells from fragility and inactivation in the tumor microenvironment
H Zhang, VS Tomar, J Li, R Basavaraja, F Yan, J Gui, N McBrearty, ...
Cancer immunology research 10 (12), 1490-1505, 2022
52022
The Role of Properdin in Killing of Non-Pathogenic Leptospira biflexa
APG Martinez, PAE Abreu, S de Arruda Vasconcellos, PL Ho, VP Ferreira, ...
Frontiers in Immunology 11, 572562, 2020
52020
Inhibitory affinity modulation of FcγRIIA ligand binding by glycosphingolipids by inside-out signaling
K Okubo, MD Brenner, X Cullere, G Saggu, ML Patchen, N Bose, S Mihori, ...
Cell reports 35 (7), 2021
42021
Humoral Pathogenesis: Fcγ Receptors in Autoimmunity and End-Organ Damage
T Ernandez, G Saggu, TN Mayadas
Systemic lupus erythematosus, 159-184, 2016
22016
Role of complement regulatory protein properdin in complement activation on platelets and in the formation of platelet-leukocyte aggregates
G Saggu
The University of Toledo, 2014
22014
Identification of a novel mode of complement activation on stimulated platelets mediated by properdin
G Saggu, C Cortes, HN Emch, G Ramirez, RG Worth, VP Ferreira
Immunobiology 11 (217), 1175-1176, 2012
12012
The Role of Properdin in Killing of
APG Martinez, PAE Abreu, S de Arruda Vasconcellos, PL Ho, VP Ferreira, ...
The Role of Complement in Microbial Infections, 2021
2021
Fcγ receptors in autoimmunity and end-organ damage
T Ernandez, K Okubo, G Saggu, TN Mayadas
Systemic Lupus Erythematosus, 179-195, 2021
2021
PKC-δ activation in neutrophils promotes fungal clearance.
LX Li Xun, X Cullere, H Nishi, G Saggu, E Durand, MK Mansour, JM Tam, ...
2016
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Статии 1–20