Chia-Lung Wu
Chia-Lung Wu
Department of Orthopaedics, Center for Musculoskeletal Research, University of Rochester
Потвърден имейл адрес: duke.edu
Osteoarthritis as a disease of the cartilage pericellular matrix
F Guilak, RJ Nims, A Dicks, CL Wu, I Meulenbelt
Matrix Biology 71, 40-50, 2018
The role of macrophages in osteoarthritis and cartilage repair
CL Wu, NS Harasymowicz, MA Klimak, KH Collins, F Guilak
Osteoarthritis and cartilage 28 (5), 544-554, 2020
Intra-articular delivery of purified mesenchymal stem cells from C57BL/6 or MRL/MpJ superhealer mice prevents posttraumatic arthritis
BO Diekman, CL Wu, CR Louer, BD Furman, JL Huebner, VB Kraus, ...
Cell transplantation 22 (8), 1395-1408, 2013
Dietary fatty acid content regulates wound repair and the pathogenesis of osteoarthritis following joint injury
CL Wu, D Jain, JN McNeill, D Little, JA Anderson, JL Huebner, VB Kraus, ...
Annals of the rheumatic diseases 74 (11), 2076-2083, 2015
Cartilage-specific knockout of the mechanosensory ion channel TRPV4 decreases age-related osteoarthritis
CJ O’Conor, S Ramalingam, NA Zelenski, HC Benefield, I Rigo, D Little, ...
Scientific reports 6 (1), 29053, 2016
Diet-induced obesity alters the differentiation potential of stem cells isolated from bone marrow, adipose tissue and infrapatellar fat pad: the effects of free fatty acids
CL Wu, BO Diekman, D Jain, F Guilak
International Journal of obesity 37 (8), 1079-1087, 2013
Conditional macrophage depletion increases inflammation and does not inhibit the development of osteoarthritis in obese macrophage Fas‐induced apoptosis–transgenic mice
CL Wu, J McNeill, K Goon, D Little, K Kimmerling, J Huebner, V Kraus, ...
Arthritis & Rheumatology 69 (9), 1772-1783, 2017
Single cell transcriptomic analysis of human pluripotent stem cell chondrogenesis
CL Wu, A Dicks, N Steward, R Tang, DB Katz, YR Choi, F Guilak
Nature communications 12 (1), 362, 2021
Step-wise chondrogenesis of human induced pluripotent stem cells and purification via a reporter allele generated by CRISPR-Cas9 genome editing
SS Adkar, CL Wu, VP Willard, A Dicks, A Ettyreddy, N Steward, N Bhutani, ...
Stem Cells 37 (1), 65-76, 2019
Differentiation of human induced pluripotent stem cells into nucleus pulposus-like cells
R Tang, L Jing, VP Willard, C Wu, F Guilak, J Chen, LA Setton
Stem cell research & therapy 9, 1-12, 2018
Serum and synovial fluid lipidomic profiles predict obesity-associated osteoarthritis, synovitis, and wound repair
CL Wu, KA Kimmerling, D Little, F Guilak
Scientific reports 7 (1), 44315, 2017
Genome engineering for personalized arthritis therapeutics
SS Adkar, JM Brunger, VP Willard, CL Wu, CA Gersbach, F Guilak
Trends in molecular medicine 23 (10), 917-931, 2017
Prospective isolation of chondroprogenitors from human iPSCs based on cell surface markers identified using a CRISPR-Cas9-generated reporter
A Dicks, CL Wu, N Steward, SS Adkar, CA Gersbach, F Guilak
Stem Cell Research & Therapy 11, 1-14, 2020
Gene therapy for follistatin mitigates systemic metabolic inflammation and post-traumatic arthritis in high-fat diet–induced obesity
R Tang, NS Harasymowicz, CL Wu, KH Collins, YR Choi, SJ Oswald, ...
Science Advances 6 (19), eaaz7492, 2020
Synovial fibroblasts assume distinct functional identities and secrete R-spondin 2 in osteoarthritis
AJ Knights, EC Farrell, OM Ellis, L Lammlin, LM Junginger, PM Rzeczycki, ...
Annals of the rheumatic diseases 82 (2), 272-282, 2023
Intra-articular depletion of macrophages increases acute synovitis and alters macrophage polarity in the injured mouse knee
KN Bailey, BD Furman, J Zeitlin, KA Kimmerling, CL Wu, F Guilak, ...
Osteoarthritis and cartilage 28 (5), 626-638, 2020
Intergenerational transmission of diet‐induced obesity, metabolic imbalance, and osteoarthritis in mice
NS Harasymowicz, YR Choi, CL Wu, L Iannucci, R Tang, F Guilak
Arthritis & Rheumatology 72 (4), 632-644, 2020
Physiologic and pathologic effects of dietary free fatty acids on cells of the joint
NS Harasymowicz, A Dicks, CL Wu, F Guilak
Annals of the New York Academy of Sciences 1440 (1), 36-53, 2019
Single-cell RNA sequencing reveals the induction of novel myeloid and myeloid-associated cell populations in visceral fat with long-term obesity
NS Harasymowicz, N Rashidi, A Savadipour, CL Wu, R Tang, J Bramley, ...
FASEB journal: official publication of the Federation of American Societies …, 2021
A Genome-engineered Bioartificial Implant for Autoregulated Anti-Cytokine Drug Delivery
FG Yun-Rak Choi, Kelsey Collins, Luke Springer, Lara Pferdehirt, Alison Ross ...
Science Advances 7 (36), eabj1414, 2021
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