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Mong-Jen Chen
Mong-Jen Chen
Senior Clinical Pharmacologist, Abbvie
Verified email at abbvie.com
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Cited by
Year
Predicting Pulmonary Pharmacokinetics from In Vitro Properties of Dry Powder Inhalers
S Bhagwat, U Schilling, MJ Chen, X Wei, R Delvadia, M Absar, B Saluja, ...
Pharmaceutical research 34, 2541-2556, 2017
502017
Microsatellite in the 3′ untranslated region of human fibroblast growth factor 9 (FGF9) gene exhibits pleiotropic effect on modulating FGF9 protein expression
TM Chen, PL Kuo, CH Hsu, SJ Tsai, MJ Chen, CW Lin, HS Sun
Human mutation 28 (1), 98-98, 2007
432007
Alpha 1 antitrypsin inhibits dendritic cell activation and attenuates nephritis in a mouse model of lupus
AS Elshikha, Y Lu, MJ Chen, M Akbar, L Zeumer, A Ritter, H Elghamry, ...
PloS one 11 (5), e0156583, 2016
382016
α-1 Antitrypsin Inhibits RANKL-induced osteoclast formation and functions
MA Akbar, D Nardo, MJ Chen, AS Elshikha, R Ahamed, EM Elsayed, ...
Molecular Medicine 23, 57-69, 2017
312017
Comparable efficacy and better safety of double β-lactam combination therapy versus β‑lactam plus aminoglycoside in gram-negative bacteria in randomized, controlled trials
Y Jiao, B Moya, MJ Chen, AP Zavascki, H Tsai, X Tao, DS Sutaria, ...
Antimicrobial Agents and Chemotherapy 63 (7), 10.1128/aac. 00425-19, 2019
302019
Alpha-1 antitrypsin gene therapy ameliorates bone loss in ovariectomy-induced osteoporosis mouse model
MA Akbar, JJ Cao, Y Lu, D Nardo, MJ Chen, AS Elshikha, R Ahamed, ...
Human Gene Therapy 27 (9), 679-686, 2016
272016
Transplantation of adipose tissue–derived mesenchymal stem cell (ATMSC) expressing alpha-1 antitrypsin reduces bone loss in ovariectomized osteoporosis mice
MA Akbar, Y Lu, AS Elshikha, MJ Chen, Y Yuan, EM Whitley, LS Holliday, ...
Human gene therapy 28 (2), 179-189, 2017
252017
In situ transplantation of alginate bioencapsulated adipose tissues derived stem cells (ADSCs) via hepatic injection in a mouse model
MJ Chen, Y Lu, NE Simpson, MJ Beveridge, AS Elshikha, MA Akbar, ...
PloS one 10 (9), e0138184, 2015
192015
Can pharmacokinetic studies assess the pulmonary fate of dry powder inhaler formulations of fluticasone propionate?
G Hochhaus, MJ Chen, A Kurumaddali, U Schilling, Y Jiao, SK Drescher, ...
The AAPS journal 23, 1-14, 2021
172021
Reprogramming adipose tissue-derived mesenchymal stem cells into pluripotent stem cells by a mutant adeno-associated viral vector
MJ Chen, Y Lu, T Hamazaki, HY Tsai, K Erger, T Conlon, AS Elshikha, ...
Human gene therapy methods 25 (1), 72-82, 2014
172014
Alpha 1 antitrypsin gene therapy extends the lifespan of lupus-prone mice
AS Elshikha, Y Yuan, Y Lu, MJ Chen, G Abboud, MA Akbar, H Plate, ...
Molecular Therapy-Methods & Clinical Development 11, 131-142, 2018
142018
Effects of lipid formulations on clove extract spray dried powders: comparison of physicochemical properties, storage stability and in vitro intestinal permeation
DF Cortes-Rojas, CRF Souza, MJ Chen, G Hochhaus, WP Oliveira
Pharmaceutical Development and Technology 23 (10), 1047-1056, 2018
102018
Alpha-1-antitrypsin ameliorates pristane induced diffuse alveolar hemorrhage in mice
AS Elshikha, G Abboud, L Van der Meijden-Erkelens, Y Lu, MJ Chen, ...
Journal of Clinical Medicine 8 (9), 1341, 2019
92019
Unraveling the pulmonary fate of fluticasone and friends: meeting the physiologic and pharmacokinetic challenges
G Hochhaus, M Chen, J Shur, A Kurumaddali, U Schilling, Y Jiao, ...
Respir Drug Deliv 2020, 139-146, 2020
52020
Fetal Concentrations of Budesonide and Fluticasone Propionate: a Study in Mice
S Zaidi, MJ Chen, DT Lee, E Neubart, P Ewing, A Miller-Larsson, ...
The AAPS Journal 21 (53), 2019
42019
Pharmacokinetic and pharmacodynamic modeling of gut hormone peptide YY(3–36) after pulmonary delivery
J Shao, MJ Chen, PJ Kuehl, G Hochhaus
Drug Development and Industrial Pharmacy, 2019
32019
Pharmacokinetics and Pharmacodynamics of Drugs Delivered to the Lung
SK Drescher, MJ Chen, JB Bulitta, G Hochhaus
Pharmaceutical Inhalation Aerosol Technology, 2019
22019
Central and peripheral lung deposition of fluticasone propionate dry powder inhaler formulations in humans characterized by population pharmacokinetics
SK Drescher, Y Jiao, MJ Chen, A Kurumaddali, J Shao, E Amini, ...
Pharmaceutical research 40 (5), 1177-1191, 2023
12023
Assessing the impact of immunogenicity and improving prediction of trough concentrations: Population pharmacokinetic modeling of adalimumab in patients with Crohn’s disease and …
AV Ponce-Bobadilla, S Stodtmann, MJ Chen, I Winzenborg, S Mensing, ...
Clinical Pharmacokinetics 62 (4), 623-634, 2023
12023
Virtual Bioequivalence Assessment of Elagolix Formulations Using Physiologically Based Pharmacokinetic Modeling
D Mukherjee, MJ Chen, X Shao, TR Ju, M Shebley, P Marroum
The AAPS Journal 25 (3), 30, 2023
12023
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