Self-sufficient control of urate homeostasis in mice by a synthetic circuit C Kemmer, M Gitzinger, M Daoud-El Baba, V Djonov, J Stelling, ... Nature biotechnology 28 (4), 355-360, 2010 | 313 | 2010 |
A synthetic mammalian gene circuit reveals antituberculosis compounds W Weber, R Schoenmakers, B Keller, M Gitzinger, T Grau, ... Proceedings of the National Academy of Sciences 105 (29), 9994-9998, 2008 | 214 | 2008 |
Reversion of antibiotic resistance in Mycobacterium tuberculosis by spiroisoxazoline SMARt-420 N Blondiaux, M Moune, M Desroses, R Frita, M Flipo, V Mathys, ... Science 355 (6330), 1206-1211, 2017 | 142 | 2017 |
Controlling transgene expression in subcutaneous implants using a skin lotion containing the apple metabolite phloretin M Gitzinger, C Kemmer, MD El-Baba, W Weber, M Fussenegger Proceedings of the National Academy of Sciences 106 (26), 10638-10643, 2009 | 128 | 2009 |
The food additive vanillic acid controls transgene expression in mammalian cells and mice M Gitzinger, C Kemmer, DA Fluri, M Daoud El-Baba, W Weber, ... Nucleic acids research 40 (5), e37-e37, 2012 | 127 | 2012 |
Dissecting colistin resistance mechanisms in extensively drug-resistant Acinetobacter baumannii clinical isolates V Trebosc, S Gartenmann, M Tötzl, V Lucchini, B Schellhorn, M Pieren, ... MBio 10 (4), 10.1128/mbio. 01083-19, 2019 | 107 | 2019 |
Functional cross‐kingdom conservation of mammalian and moss (Physcomitrella patens) transcription, translation and secretion machineries M Gitzinger, J Parsons, R Reski, M Fussenegger Plant biotechnology journal 7 (1), 73-86, 2009 | 50 | 2009 |
A novel genome-editing platform for drug-resistant Acinetobacter baumannii reveals an AdeR-unrelated tigecycline resistance mechanism V Trebosc, S Gartenmann, K Royet, P Manfredi, M Tötzl, B Schellhorn, ... Antimicrobial agents and chemotherapy 60 (12), 7263-7271, 2016 | 45 | 2016 |
In vitro activity of rifabutin against 293 contemporary carbapenem-resistant Acinetobacter baumannii clinical isolates and characterization of rifabutin mode of … V Trebosc, B Schellhorn, J Schill, V Lucchini, J Bühler, M Bourotte, ... Journal of Antimicrobial Chemotherapy 75 (12), 3552-3562, 2020 | 28 | 2020 |
Composition for treatment of tuberculosis R Schoenmakers, W Weber, M Gitzinger, M Fussenegger, M Tigges, ... US Patent 8,912,329, 2014 | 23 | 2014 |
Phenylethyl butyrate enhances the potency of second-line drugs against clinical isolates of Mycobacterium tuberculosis T Grau, P Selchow, M Tigges, R Burri, M Gitzinger, EC Böttger, ... Antimicrobial agents and chemotherapy 56 (2), 1142-1145, 2012 | 21 | 2012 |
A fragment-based approach towards the discovery of N-substituted tropinones as inhibitors of Mycobacterium tuberculosis transcriptional regulator EthR2 H Prevet, M Moune, A Tanina, C Kemmer, A Herledan, R Frita, ... European journal of medicinal chemistry 167, 426-438, 2019 | 16 | 2019 |
The small-molecule SMARt751 reverses Mycobacterium tuberculosis resistance to ethionamide in acute and chronic mouse models of tuberculosis M Flipo, R Frita, M Bourotte, MS Martínez-Martínez, M Boesche, GW Boyle, ... Science Translational Medicine 14 (643), eaaz6280, 2022 | 15 | 2022 |
The Role of OmpR in Bile Tolerance and Pathogenesis of Adherent-Invasive Escherichia coli V Lucchini, A Sivignon, M Pieren, M Gitzinger, S Lociuro, N Barnich, ... Frontiers in Microbiology 12, 684473, 2021 | 10 | 2021 |
Rifabutin for infusion (BV100) for the treatment of severe carbapenem-resistant Acinetobacter baumannii infections V Trebosc, C Kemmer, S Lociuro, M Gitzinger, GE Dale Drug Discovery Today 26 (9), 2099-2104, 2021 | 9 | 2021 |
Design and synthesis of water-soluble prodrugs of rifabutin for intraveneous administration K Antraygues, M Maingot, B Schellhorn, V Trebosc, M Gitzinger, B Deprez, ... European Journal of Medicinal Chemistry 238, 114515, 2022 | 7 | 2022 |
Targeting virulence regulation to disarm Acinetobacter baumannii pathogenesis V Trebosc, V Lucchini, M Narwal, B Wicki, S Gartenmann, B Schellhorn, ... Virulence 13 (1), 1868-1883, 2022 | 3 | 2022 |
Composition for treatment of tuberculosis R Schoenmakers, W Weber, M Gitzinger, M Fussenegger, M Tigges, ... | 3 | 2010 |
In vivo efficacy of BV100 in mouse models of Acinetobacter baumannii infections GE Dale, C Kemmer, V Trebosc, B Schellhorn, M Gitzinger, S Lociuro, ... ECCMID 2021 congress, 2021 | 2 | 2021 |
Structure-activity relationships of actively FhuE transported rifabutin derivatives with potent activity against Acinetobacter baumannii M Maingot, M Bourotte, AC Vetter, B Schellhorn, K Antraygues, H Scherer, ... European Journal of Medicinal Chemistry 252, 115257, 2023 | 1 | 2023 |